C9ORF72 GGGGCC repeat-associated non-AUG translation is upregulated by stress through eIF2α phosphorylation

por Cheng, Weiwei, Wang, Shaopeng, Mestre, Alexander A., Fu, Chenglai, Makarem, Andres, Xian, Fengfan, Hayes, Lindsey R., Lopez-Gonzalez, Rodrigo, Drenner, Kevin, Jiang, Jie, Cleveland, Don W., Sun, Shuying
Publicado 2018

Mutant TDP-43 within motor neurons drives disease onset but not progression in amyotrophic lateral sclerosis

por Ditsworth, Dara, Maldonado, Marcus, McAlonis-Downes, Melissa, Sun, Shuying, Seelman, Amanda, Drenner, Kevin, Arnold, Eveline, Ling, Shuo-Chien, Pizzo, Donald, Ravits, John, Cleveland, Don W., Da Cruz, Sandrine
Publicado 2017

The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

por Drenner, Kevin, Basu, Gargi D., Goodman, Laurie J., Ozols, Audrey A., LoBello, Janine R., Royce, Thomas, Gordon, Michael S., Borazanci, Erkut H., Steinbach, Margaux A., Trent, Jeffrey, Sharma, Sunil
Publicado 2021

Addendum: The value of comprehensive genomic sequencing to maximize the identification of clinically actionable alterations in advanced cancer patients: a case series

por Drenner, Kevin, Basu, Gargi D., Goodman, Laurie J., Ozols, Audrey A., LoBello, Janine R., Royce, Thomas, Gordon, Michael S., Borazanci, Erkut H., Steinbach, Margaux A., Trent, Jeffrey, Sharma, Sunil
Publicado 2022

Motor neuron intrinsic and extrinsic mechanisms contribute to the pathogenesis of FUS-associated amyotrophic lateral sclerosis

por Scekic-Zahirovic, Jelena, Oussini, Hajer El, Mersmann, Sina, Drenner, Kevin, Wagner, Marina, Sun, Ying, Allmeroth, Kira, Dieterlé, Stéphane, Sinniger, Jérôme, Dirrig-Grosch, Sylvie, René, Frédérique, Dormann, Dorothee, Haass, Christian, Ludolph, Albert C., Lagier-Tourenne, Clotilde, Storkebaum, Erik, Dupuis, Luc
Publicado 2017

The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer

por Soldi, Raffaella, Ghosh Halder, Tithi, Weston, Alexis, Thode, Trason, Drenner, Kevin, Lewis, Rhonda, Kaadige, Mohan R., Srivastava, Shreyesi, Daniel Ampanattu, Sherin, Rodriguez del Villar, Ryan, Lang, Jessica, Vankayalapati, Hariprasad, Weissman, Bernard, Trent, Jeffrey M., Hendricks, William P. D., Sharma, Sunil
Publicado 2020

Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration

por Melamed, Ze’ev, Lopez-Erauskin, Jone, Baughn, Michael W., Zhang, Ouyang, Drenner, Kevin, Sun, Ying, Freyermuth, Fernande, McMahon, Moira A., Beccari, Melinda S, Artates, Jon, Ohkubo, Takuya, Rodriguez, Maria, Lin, Nianwei, Wu, Dongmei, Bennett, C. Frank, Rigo, Frank, Da Cruz, Sandrine, Ravits, John, Lagier-Tourenne, Clotilde, Cleveland, Don W.
Publicado 2019

Canine osteosarcoma genome sequencing identifies recurrent mutations in DMD and the histone methyltransferase gene SETD2

por Gardner, Heather L., Sivaprakasam, Karthigayini, Briones, Natalia, Zismann, Victoria, Perdigones, Nieves, Drenner, Kevin, Facista, Salvatore, Richholt, Ryan, Liang, Winnie, Aldrich, Jessica, Trent, Jeffrey M., Shields, Peter G., Robinson, Nicholas, Johnson, Jeremy, Lana, Susan, Houghton, Peter, Fenger, Joelle, Lorch, Gwendolen, Janeway, Katherine A., London, Cheryl A., Hendricks, William P. D.
Publicado 2019

Toxic gain of function from mutant FUS protein is crucial to trigger cell autonomous motor neuron loss

por Scekic‐Zahirovic, Jelena, Sendscheid, Oliver, El Oussini, Hajer, Jambeau, Mélanie, Sun, Ying, Mersmann, Sina, Wagner, Marina, Dieterlé, Stéphane, Sinniger, Jérome, Dirrig‐Grosch, Sylvie, Drenner, Kevin, Birling, Marie‐Christine, Qiu, Jinsong, Zhou, Yu, Li, Hairi, Fu, Xiang‐Dong, Rouaux, Caroline, Shelkovnikova, Tatyana, Witting, Anke, Ludolph, Albert C, Kiefer, Friedemann, Storkebaum, Erik, Lagier‐Tourenne, Clotilde, Dupuis, Luc
Publicado 2016