High throughput chemical library screening identifies a novel p110-δ inhibitor that potentiates the anti-myeloma effect of bortezomib

por Malek, Ehsan, Driscoll, James J.
Publicado 2016

Shutting off the fuel supply to target metabolic vulnerabilities in multiple myeloma

por Rana, Priyanka S., Goparaju, Krishna, Driscoll, James J.
Publicado 2023

MicroRNAs in Brain Metastases: Potential Role as Diagnostics and Therapeutics

por Alsidawi, Samer, Malek, Ehsan, Driscoll, James J.
Publicado 2014

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer

por Malek, Ehsan, Jagannathan, Sajjeev, Driscoll, James J.
Publicado 2014

Therapeutics to harness the immune microenvironment in multiple myeloma

por Ignatz-Hoover, James J., Driscoll, James J.
Publicado 2022

Mechanistic and Treatment Implications of ΔNp63 Expression in a Rare Case of Metastatic Hidradenocarcinoma

por Driscoll, James J., Gauerke, Steven, Monahan, Brian C.
Publicado 2009

Identification of Long Non-Coding RNAs Deregulated in Multiple Myeloma Cells Resistant to Proteasome Inhibitors

por Malek, Ehsan, Kim, Byung-Gyu, Driscoll, James J.
Publicado 2016

Targeting Proteasomes in Cancer and Infectious Disease: A Parallel Strategy to Treat Malignancies and Microbes

por Ignatz-Hoover, James J., Murphy, Elena V., Driscoll, James J.
Publicado 2022

Road testing new CAR design strategies in multiple myeloma

por Rana, Priyanka S., Murphy, Elena V., Kort, Jeries, Driscoll, James J.
Publicado 2022

Targeting TGF-β signaling in the multiple myeloma microenvironment: Steering CARs and T cells in the right direction

por Rana, Priyanka S., Soler, David C., Kort, Jeries, Driscoll, James J.
Publicado 2022

Current and Emerging Strategies to Treat Urothelial Carcinoma

por Rani, Berkha, Ignatz-Hoover, James J., Rana, Priyanka S., Driscoll, James J.
Publicado 2023

Bortezomib induces AMPK-dependent autophagosome formation uncoupled from apoptosis in drug resistant cells

por Jaganathan, Sajjeev, Malek, Ehsan, Vallabhapurapu, Subrahmanya, Vallabhapurapu, Sivakumar, Driscoll, James J.
Publicado 2014

Deciphering mechanisms of immune escape to inform immunotherapeutic strategies in multiple myeloma

por Swamydas, Muthulekha, Murphy, Elena V., Ignatz-Hoover, James J., Malek, Ehsan, Driscoll, James J.
Publicado 2022

Rare Extraperitoneal Involvement with Fatal Outcome in a Case of Bilateral Luteinized Thecoma of the Ovaries with Sclerosing Peritonitis

por Medhat, Mohamed A., Abdel Malek, Mohamed A. Y., Zaki, Saad, Helmy, Ahmed, Driscoll, James J.
Publicado 2014

Novel therapies emerging in oncology to target the TGF-β pathway

por Kim, Byung-Gyu, Malek, Ehsan, Choi, Sung Hee, Ignatz-Hoover, James J., Driscoll, James J.
Publicado 2021

Transcriptional Repression of Bim by a Novel YY1-RelA Complex Is Essential for the Survival and Growth of Multiple Myeloma

por Potluri, Veena, Noothi, Sunil K., Vallabhapurapu, Subrahmanya D., Yoon, Sang-Oh, Driscoll, James J., Lawrie, Charles H., Vallabhapurapu, Sivakumar
Publicado 2013

The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis

por Subramani, Arasukumar, Alsidawi, Samer, Jagannathan, Sajjeev, Sumita, Kazutaka, Sasaki, Atsuo T., Aronow, Bruce, Warnick, Ronald E., Lawler, Sean, Driscoll, James J.
Publicado 2013

Rb Suppresses Collective Invasion, Circulation and Metastasis of Breast Cancer Cells in CD44-Dependent Manner

por Kim, Kui-Jin, Godarova, Alzbeta, Seedle, Kari, Kim, Min-Ho, Ince, Tan A., Wells, Susanne I., Driscoll, James J., Godar, Samuel
Publicado 2013

Predicting Successful Phase Advancement and Regulatory Approval in Multiple Myeloma From Phase I Overall Response Rates

por Malek, Ehsan, Saygin, Caner, Ye, Rebecca, Covut, Fahrettin, Kim, Byung-Gyu, Welge, Jeffrey, Meropol, Neal J., De Lima, Marcos, Driscoll, James J.
Publicado 2017

Vactosertib, a novel TGF-β1 type I receptor kinase inhibitor, improves T-cell fitness: a single-arm, phase 1b trial in relapsed/refractory multiple myeloma

por Malek, Ehsan, Rana, Priyanka S., Swamydas, Muthulekha, Daunov, Michael, Miyagi, Masaru, Murphy, Elena, Ignatz-Hoover, James J., Metheny, Leland, Seong Jin, Kim, Driscoll, James J.
Publicado 2023