Structural and Functional Characterization of the Recombinant Death Domain from Death-Associated Protein Kinase

por Dioletis, Evangelos, Dingley, Andrew J., Driscoll, Paul C.
Publicado 2013

Crystal structures of PI3K-C2α PX domain indicate conformational change associated with ligand binding

por Parkinson, Gary N, Vines, David, Driscoll, Paul C, Djordjevic, Snezana
Publicado 2008

Volume Determination with Two Standards Allows Absolute Quantification and Improved Chemometric Analysis of Metabolites by NMR from Submicroliter Samples

por Ragan, Timothy J., Bailey, Andrew P., Gould, Alex P., Driscoll, Paul C.
Publicado 2013

Solution Structure and Phylogenetics of Prod1, a Member of the Three-Finger Protein Superfamily Implicated in Salamander Limb Regeneration

por Garza-Garcia, Acely, Harris, Richard, Esposito, Diego, Gates, Phillip B., Driscoll, Paul C.
Publicado 2009

An Improved Method for Measuring Absolute Metabolite Concentrations in Small Biofluid or Tissue Samples

por Fernando, Tharindu, Sawala, Annick, Bailey, Andrew P., Gould, Alex P., Driscoll, Paul C.
Publicado 2019

Dynamic Allostery in PLCγ1 and Its Modulation by a Cancer Mutation Revealed by MD Simulation and NMR

por Koss, Hans, Bunney, Tom D., Esposito, Diego, Martins, Marta, Katan, Matilda, Driscoll, Paul C.
Publicado 2018

Ligand-Dependent Dynamics of the Active-Site Lid in Bacterial Dimethylarginine Dimethylaminohydrolase

por Rasheed, Masooma, Richter, Christine, Chisty, Liisa T., Kirkpatrick, John, Blackledge, Martin, Webb, Martin R., Driscoll, Paul C.
Publicado 2014

Flexible Stoichiometry and Asymmetry of the PIDDosome Core Complex by Heteronuclear NMR Spectroscopy and Mass Spectrometry

por Nematollahi, Lily A., Garza-Garcia, Acely, Bechara, Chérine, Esposito, Diego, Morgner, Nina, Robinson, Carol V., Driscoll, Paul C.
Publicado 2015

Developmental diet regulates Drosophila lifespan via lipid autotoxins

por Stefana, M. Irina, Driscoll, Paul C., Obata, Fumiaki, Pengelly, Ana Raquel, Newell, Clare L., MacRae, James I., Gould, Alex P.
Publicado 2017

Mechanism of Action of Secreted Newt Anterior Gradient Protein

por Grassme, Kathrin S., Garza-Garcia, Acely, Delgado, Jean-Paul, Godwin, James W., Kumar, Anoop, Gates, Phillip B., Driscoll, Paul C., Brockes, Jeremy P.
Publicado 2016

The impact of physiological metabolite levels on serine uptake, synthesis and utilization in cancer cells

por Hennequart, Marc, Labuschagne, Christiaan F., Tajan, Mylène, Pilley, Steven E., Cheung, Eric C., Legrave, Nathalie M., Driscoll, Paul C., Vousden, Karen H.
Publicado 2021

An engineered photoswitchable mammalian pyruvate kinase

por Gehrig, Stefanie, Macpherson, Jamie A., Driscoll, Paul C., Symon, Alastair, Martin, Stephen R., MacRae, James I., Kleinjung, Jens, Fraternali, Franca, Anastasiou, Dimitrios
Publicado 2017

Evaluating the conformation of recombinant domain I of β(2)-glycoprotein I and its interaction with human monoclonal antibodies

por Pericleous, Charis, Miles, Jennifer, Esposito, Diego, Garza-Garcia, Acely, Driscoll, Paul C., Lambrianides, Anastasia, Latchman, David, Isenberg, David, Rahman, Anisur, Ioannou, Yiannis, Giles, Ian
Publicado 2011

Structural and Functional Integration of the PLCγ Interaction Domains Critical for Regulatory Mechanisms and Signaling Deregulation

por Bunney, Tom D., Esposito, Diego, Mas-Droux, Corine, Lamber, Ekatarina, Baxendale, Rhona W., Martins, Marta, Cole, Ambrose, Svergun, Dmitri, Driscoll, Paul C., Katan, Matilda
Publicado 2012

Rac Regulates Its Effector Phospholipase Cγ(2) through Interaction with a Split Pleckstrin Homology Domain

por Walliser, Claudia, Retlich, Michael, Harris, Richard, Everett, Katy L., Josephs, Michelle B., Vatter, Petra, Esposito, Diego, Driscoll, Paul C., Katan, Matilda, Gierschik, Peter, Bunney, Tom D.
Publicado 2008

Characterization of Vibrio cholerae Hfq Provides Novel Insights into the Role of the Hfq C-Terminal Region

por Vincent, Helen A., Henderson, Charlotte A., Ragan, Timothy J., Garza-Garcia, Acely, Cary, Peter D., Gowers, Darren M., Malfois, Marc, Driscoll, Paul C., Sobott, Frank, Callaghan, Anastasia J.
Publicado 2012

Functional cross-talk between allosteric effects of activating and inhibiting ligands underlies PKM2 regulation

por Macpherson, Jamie A, Theisen, Alina, Masino, Laura, Fets, Louise, Driscoll, Paul C, Encheva, Vesela, Snijders, Ambrosius P, Martin, Stephen R, Kleinjung, Jens, Barran, Perdita E, Fraternali, Franca, Anastasiou, Dimitrios
Publicado 2019

Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of β(2)-glycoprotein I in a mouse model of anti-phospholipid antibod...

por Pericleous, Charis, Ruiz-Limón, Patricia, Romay-Penabad, Zurina, Marín, Ana Carrera, Garza-Garcia, Acely, Murfitt, Lucy, Driscoll, Paul C., Latchman, David S., Isenberg, David A., Giles, Ian, Ioannou, Yiannis, Rahman, Anisur, Pierangeli, Silvia S.
Publicado 2015

Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells

por Ch, Ratnasekhar, Rey, Guillaume, Ray, Sandipan, Jha, Pawan K., Driscoll, Paul C., Dos Santos, Mariana Silva, Malik, Dania M., Lach, Radoslaw, Weljie, Aalim M., MacRae, James I., Valekunja, Utham K., Reddy, Akhilesh B.
Publicado 2021

Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction

por Jarvis, Ashley, Allerston, Charles K., Jia, Haiyan, Herzog, Birger, Garza-Garcia, Acely, Winfield, Natalie, Ellard, Katie, Aqil, Rehan, Lynch, Rosemary, Chapman, Chris, Hartzoulakis, Basil, Nally, James, Stewart, Mark, Cheng, Lili, Menon, Malini, Tickner, Michelle, Djordjevic, Snezana, Driscoll, Paul C., Zachary, Ian, Selwood, David L.
Publicado 2010