Targeting KRAS mutant lung cancer: light at the end of the tunnel

por Drosten, Matthias, Barbacid, Mariano
Publicado 2022

KRAS inhibitors: going noncovalent

por Drosten, Matthias, Barbacid, Mariano
Publicado 2022

Ras in epidermal proliferation

por Drosten, Matthias, Lechuga, Carmen G., Barbacid, Mariano
Publicado 2014

Reversible, interrelated mRNA and miRNA expression patterns in the transcriptome of Rasless fibroblasts: functional and mechanistic implications

por Azrak, Sami S, Ginel-Picardo, Alicia, Drosten, Matthias, Barbacid, Mariano, Santos, Eugenio
Publicado 2013

Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes

por Shahbazi, Marta N., Peña-Jimenez, Daniel, Antonucci, Francesca, Drosten, Matthias, Perez-Moreno, Mirna
Publicado 2017

A new mode of DNA binding distinguishes Capicua from other HMG-box factors and explains its mutation patterns in cancer

por Forés, Marta, Simón-Carrasco, Lucía, Ajuria, Leiore, Samper, Núria, González-Crespo, Sergio, Drosten, Matthias, Barbacid, Mariano, Jiménez, Gerardo
Publicado 2017

Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma

por Simón-Carrasco, Lucía, Graña, Osvaldo, Salmón, Marina, Jacob, Harrys K.C., Gutierrez, Alejandro, Jiménez, Gerardo, Drosten, Matthias, Barbacid, Mariano
Publicado 2017

ERF deletion rescues RAS deficiency in mouse embryonic stem cells

por Mayor-Ruiz, Cristina, Olbrich, Teresa, Drosten, Matthias, Lecona, Emilio, Vega-Sendino, Maria, Ortega, Sagrario, Dominguez, Orlando, Barbacid, Mariano, Ruiz, Sergio, Fernandez-Capetillo, Oscar
Publicado 2018

KSR induces RAS‐independent MAPK pathway activation and modulates the efficacy of KRAS inhibitors

por Paniagua, Guillem, Jacob, Harrys K.C., Brehey, Oksana, García‐Alonso, Sara, Lechuga, Carmen G., Pons, Tirso, Musteanu, Monica, Guerra, Carmen, Drosten, Matthias, Barbacid, Mariano
Publicado 2022

Kras oncogene ablation prevents resistance in advanced lung adenocarcinomas

por Salmón, Marina, Álvarez-Díaz, Ruth, Fustero-Torre, Coral, Brehey, Oksana, Lechuga, Carmen G., Sanclemente, Manuel, Fernández-García, Fernando, López-García, Alejandra, Martín-Guijarro, María Carmen, Rodríguez-Perales, Sandra, Bousquet-Mur, Emily, Morales-Cacho, Lucía, Mulero, Francisca, Al-Shahrour, Fátima, Martínez, Lola, Domínguez, Orlando, Caleiras, Eduardo, Ortega, Sagrario, Guerra, Carmen, Musteanu, Monica, Drosten, Matthias, Barbacid, Mariano
Publicado 2023

Signature-driven repurposing of Midostaurin for combination with MEK1/2 and KRASG12C inhibitors in lung cancer

por Macaya, Irati, Roman, Marta, Welch, Connor, Entrialgo-Cadierno, Rodrigo, Salmon, Marina, Santos, Alba, Feliu, Iker, Kovalski, Joanna, Lopez, Ines, Rodriguez-Remirez, Maria, Palomino-Echeverria, Sara, Lonfgren, Shane M., Ferrero, Macarena, Calabuig, Silvia, Ludwig, Iziar A., Lara-Astiaso, David, Jantus-Lewintre, Eloisa, Guruceaga, Elizabeth, Narayanan, Shruthi, Ponz-Sarvise, Mariano, Pineda-Lucena, Antonio, Lecanda, Fernando, Ruggero, Davide, Khatri, Purvesh, Santamaria, Enrique, Fernandez-Irigoyen, Joaquin, Ferrer, Irene, Paz-Ares, Luis, Drosten, Matthias, Barbacid, Mariano, Gil-Bazo, Ignacio, Vicent, Silve
Publicado 2023