Mapping the Proteoform Landscape of Five Human Tissues

por Drown, Bryon S., Jooß, Kevin, Melani, Rafael D., Lloyd-Jones, Cameron, Camarillo, Jeannie M., Kelleher, Neil L.
Publicado 2022

(ADP-ribosyl)hydrolases: Structural Basis for Differential Substrate Recognition and Inhibition

por Rack, Johannes Gregor Matthias, Ariza, Antonio, Drown, Bryon S., Henfrey, Callum, Bartlett, Edward, Shirai, Tomohiro, Hergenrother, Paul J., Ahel, Ivan
Publicado 2018

Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens

por Parker, Erica N., Drown, Bryon S., Geddes, Emily J., Lee, Hyang Yeon, Ismail, Nahed, Lau, Gee W., Hergenrother, Paul J.
Publicado 2019

A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain

por Anmangandla, Ananya, Jana, Sadhan, Peng, Kewen, Wallace, Shamar D., Bagde, Saket R., Drown, Bryon S., Xu, Jiashu, Hergenrother, Paul J., Fromme, J. Christopher, Lin, Hening
Publicado 2023

Mapping the KRAS proteoform landscape in colorectal cancer identifies truncated KRAS4B that decreases MAPK signaling

por Adams, Lauren M., DeHart, Caroline J., Drown, Bryon S., Anderson, Lissa C., Bocik, William, Boja, Emily S., Hiltke, Tara M., Hendrickson, Christopher L., Rodriguez, Henry, Caldwell, Michael, Vafabakhsh, Reza, Kelleher, Neil L.
Publicado 2022

Highly multiplexed, label-free proteoform imaging of tissues by individual ion mass spectrometry

por Su, Pei, McGee, John P., Durbin, Kenneth R., Hollas, Michael A. R., Yang, Manxi, Neumann, Elizabeth K., Allen, Jamie L., Drown, Bryon S., Butun, Fatma Ayaloglu, Greer, Joseph B., Early, Bryan P., Fellers, Ryan T., Spraggins, Jeffrey M., Laskin, Julia, Camarillo, Jeannie M., Kafader, Jared O., Kelleher, Neil L.
Publicado 2022