Kinase Inhibitor Therapy in CML: It's What's Inside That Counts

por Eide, Christopher A., Druker, Brian J., O'Hare, Thomas
Publicado 2013

Navigating Challenges in Monitoring Chronic Myeloid Leukemia with Multiple BCR-ABL1 Transcripts

por Smith, Brittany M., Brewer, Diana, Druker, Brian J., Braun, Theodore P.
Publicado 2021

Inhibition of p38 MAPK Suppresses Inflammatory Cytokine Induction by Etoposide, 5-Fluorouracil, and Doxorubicin without Affecting Tumoricidal Activity

por Elsea, Collin R., Roberts, Daniel A., Druker, Brian J., Wood, Lisa J.
Publicado 2008

Revisiting NTRKs as an emerging oncogene in hematological malignancies

por Joshi, Sunil K., Davare, Monika A., Druker, Brian J., Tognon, Cristina E.
Publicado 2019

In vitro sensitivity to dasatinib in lymphoblasts from a patient with t(17;19)(q22;p13) gene rearrangement pre-B acute lymphoblastic leukemia

por Glover, Jason M, Loriaux, Marc, Tyner, Jeffrey W, Druker, Brian J, Chang, Bill H
Publicado 2012

Functional characterization of two rare BCR–FGFR1(+) leukemias

por Barnes, Evan J., Leonard, Jessica, Medeiros, Bruno C., Druker, Brian J., Tognon, Cristina E.
Publicado 2020

Outgrowth of a CSF3R-mutant clone drives a second myeloproliferative neoplasm in a chronic myeloid leukemia patient: a case report

por Carratt, Sarah A., Brewer, Diana, Maxson, Julia E., Druker, Brian J., Braun, Theodore P.
Publicado 2021

Discovery and functional characterization of a germline, CSF2RB-activating mutation in leukemia

por Watanabe-Smith, Kevin, Tognon, Cristina, Tyner, Jeffrey W., Meijerink, Jules P.P., Druker, Brian J., Agarwal, Anupriya
Publicado 2016

Genomic markers of midostaurin drug sensitivity in FLT3 mutated and FLT3 wild-type acute myeloid leukemia patients

por Rosenberg, Mara W., Watanabe-Smith, Kevin, Tyner, Jeffrey W., Tognon, Cristina E., Druker, Brian J., Borate, Uma
Publicado 2020

A BCR-ABL Mutant Lacking Direct Binding Sites for the GRB2, CBL and CRKL Adapter Proteins Fails to Induce Leukemia in Mice

por Johnson, Kara J., Griswold, Ian J., O'Hare, Thomas, Corbin, Amie S., Loriaux, Marc, Deininger, Michael W., Druker, Brian J.
Publicado 2009

HitWalker: variant prioritization for personalized functional cancer genomics

por Bottomly, Daniel, Wilmot, Beth, Tyner, Jeffrey W., Eide, Christopher A., Loriaux, Marc M., Druker, Brian J., McWeeney, Shannon K.
Publicado 2013

Significant clinical response to JAK1/2 inhibition in a patient with CSF3R-T618I-positive atypical chronic myeloid leukemia

por Dao, Kim-Hien T., Solti, Magdolna B., Maxson, Julia E., Winton, Elliott F., Press, Richard D., Druker, Brian J., Tyner, Jeffrey W.
Publicado 2014

Durable Disease Control with MEK Inhibition in a Patient with NRAS-mutated Atypical Chronic Myeloid Leukemia

por Khanna, Vishesh, Pierce, Scott T, Dao, Kim-Hien T, Tognon, Cristina E, Hunt, David E, Junio, Brian, Tyner, Jeffrey W, Druker, Brian J
Publicado 2015

Ultrasensitive proteomic quantitation of cellular signaling by digitized nanoparticle-protein counting

por Jacob, Thomas, Agarwal, Anupriya, Ramunno-Johnson, Damien, O’Hare, Thomas, Gönen, Mehmet, Tyner, Jeffrey W., Druker, Brian J., Vu, Tania Q.
Publicado 2016

The combination of NPM1, DNMT3A, and IDH1/2 mutations leads to inferior overall survival in AML

por Dunlap, Jennifer B., Leonard, Jessica, Rosenberg, Mara, Cook, Rachel, Press, Richard, Fan, Guang, Raess, Philipp W., Druker, Brian J., Traer, Elie
Publicado 2019

Growth Arrest of BCR-ABL Positive Cells with a Sequence-Specific Polyamide-Chlorambucil Conjugate

por Chou, C. James, O'Hare, Thomas, Lefebvre, Sophie, Alvarez, David, Tyner, Jeffrey W., Eide, Christopher A., Druker, Brian J., Gottesfeld, Joel M.
Publicado 2008

Abnormal developmental control of replication-timing domains in pediatric acute lymphoblastic leukemia

por Ryba, Tyrone, Battaglia, Dana, Chang, Bill H., Shirley, James W., Buckley, Quinton, Pope, Benjamin D., Devidas, Meenakshi, Druker, Brian J., Gilbert, David M.
Publicado 2012

Comparison of methods to identify aberrant expression patterns in individual patients: augmenting our toolkit for precision medicine

por Bottomly, Daniel, Ryabinin, Peter A, Tyner, Jeffrey W, Chang, Bill H, Loriaux, Marc M, Druker, Brian J, McWeeney, Shannon K, Wilmot, Beth
Publicado 2013

Small molecule inhibitor screen identifies synergistic activity of the bromodomain inhibitor CPI203 and bortezomib in drug resistant myeloma

por Siegel, Matthew B., Liu, Selina Qiuying, Davare, Monika A., Spurgeon, Stephen E., Loriaux, Marc M., Druker, Brian J., Scott, Emma C., Tyner, Jeffrey W.
Publicado 2015

The PI3K/Akt1 pathway enhances steady-state levels of FANCL

por Dao, Kim-Hien T., Rotelli, Michael D., Brown, Brieanna R., Yates, Jane E., Rantala, Juha, Tognon, Cristina, Tyner, Jeffrey W., Druker, Brian J., Bagby, Grover C.
Publicado 2013