Strategies for translating proteomics discoveries into drug discovery for dementia

por Halder, Aditi, Drummond, Eleanor
Publicado 2023

The use of localized proteomics to identify the drivers of Alzheimer's disease pathogenesis

por Drummond, Eleanor, Wisniewski, Thomas
Publicado 2017

APOE-amyloid interaction: Therapeutic targets

por Wisniewski, Thomas, Drummond, Eleanor
Publicado 2020

It takes more than tau to tangle: using proteomics to determine how phosphorylated tau mediates toxicity in neurodegenerative diseases

por Pires, Geoffrey, Drummond, Eleanor
Publicado 2021

Tau interactome and RNA binding proteins in neurodegenerative diseases

por Kavanagh, Tomas, Halder, Aditi, Drummond, Eleanor
Publicado 2022

Proteomic analysis of neurons microdissected from formalin-fixed, paraffin-embedded Alzheimer’s disease brain tissue

por Drummond, Eleanor S, Nayak, Shruti, Ueberheide, Beatrix, Wisniewski, Thomas
Publicado 2015

Long-Term Gene Therapy Causes Transgene-Specific Changes in the Morphology of Regenerating Retinal Ganglion Cells

por Rodger, Jennifer, Drummond, Eleanor S., Hellström, Mats, Robertson, Donald, Harvey, Alan R.
Publicado 2012

Compilation of reported protein changes in the brain in Alzheimer’s disease

por Askenazi, Manor, Kavanagh, Tomas, Pires, Geoffrey, Ueberheide, Beatrix, Wisniewski, Thomas, Drummond, Eleanor
Publicado 2023

Pathology Associated with AAV Mediated Expression of Beta Amyloid or C100 in Adult Mouse Hippocampus and Cerebellum

por Drummond, Eleanor S., Muhling, Jill, Martins, Ralph N., Wijaya, Linda K., Ehlert, Erich M., Harvey, Alan R.
Publicado 2013

Secernin-1 is a novel phosphorylated tau binding protein that accumulates in Alzheimer’s disease and not in other tauopathies

por Pires, Geoffrey, McElligott, Sacha, Drusinsky, Shiron, Halliday, Glenda, Potier, Marie-Claude, Wisniewski, Thomas, Drummond, Eleanor
Publicado 2019

Tau phosphorylation induced by severe closed head traumatic brain injury is linked to the cellular prion protein

por Rubenstein, Richard, Chang, Binggong, Grinkina, Natalia, Drummond, Eleanor, Davies, Peter, Ruditzky, Meir, Sharma, Deep, Wang, Kevin, Wisniewski, Thomas
Publicado 2017

Anti-β-sheet conformation monoclonal antibody reduces tau and Aβ oligomer pathology in an Alzheimer’s disease model

por Goñi, Fernando, Martá-Ariza, Mitchell, Herline, Krystal, Peyser, Daniel, Boutajangout, Allal, Mehta, Pankaj, Drummond, Eleanor, Prelli, Frances, Wisniewski, Thomas
Publicado 2018

The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome

por Drummond, Eleanor, Kavanagh, Tomas, Pires, Geoffrey, Marta-Ariza, Mitchell, Kanshin, Evgeny, Nayak, Shruti, Faustin, Arline, Berdah, Valentin, Ueberheide, Beatrix, Wisniewski, Thomas
Publicado 2022

Blood-Based Transcriptomic Biomarkers Are Predictive of Neurodegeneration Rather Than Alzheimer’s Disease

por Shvetcov, Artur, Thomson, Shannon, Spathos, Jessica, Cho, Ann-Na, Wilkins, Heather M., Andrews, Shea J., Delerue, Fabien, Couttas, Timothy A., Issar, Jasmeen Kaur, Isik, Finula, Kaur, Simranpreet, Drummond, Eleanor, Dobson-Stone, Carol, Duffy, Shantel L., Rogers, Natasha M., Catchpoole, Daniel, Gold, Wendy A., Swerdlow, Russell H., Brown, David A., Finney, Caitlin A.
Publicado 2023

Proteomics and Transcriptomics of the Hippocampus and Cortex in SUDEP and High-Risk SUDEP Patients

por Leitner, Dominique F., Mills, James D., Pires, Geoffrey, Faustin, Arline, Drummond, Eleanor, Kanshin, Evgeny, Nayak, Shruti, Askenazi, Manor, Verducci, Chloe, Chen, Bei Jun, Janitz, Michael, Anink, Jasper J., Baayen, Johannes C., Idema, Sander, van Vliet, Erwin A., Devore, Sasha, Friedman, Daniel, Diehl, Beate, Scott, Catherine, Thijs, Roland, Wisniewski, Thomas, Ueberheide, Beatrix, Thom, Maria, Aronica, Eleonora, Devinsky, Orrin
Publicado 2021