Glucose depletion activates mmu-miR-466h-5p expression through oxidative stress and inhibition of histone deacetylation

por Druz, Aliaksandr, Betenbaugh, Michael, Shiloach, Joseph
Publicado 2012

CHO microRNA engineering is growing up: Recent successes and future challenges()

por Jadhav, Vaibhav, Hackl, Matthias, Druz, Aliaksandr, Shridhar, Smriti, Chung, Cheng-Yu, Heffner, Kelley M., Kreil, David P., Betenbaugh, Mike, Shiloach, Joseph, Barron, Niall, Grillari, Johannes, Borth, Nicole
Publicado 2013

Transplanting Supersites of HIV-1 Vulnerability

por Zhou, Tongqing, Zhu, Jiang, Yang, Yongping, Gorman, Jason, Ofek, Gilad, Srivatsan, Sanjay, Druz, Aliaksandr, Lees, Christopher R., Lu, Gabriel, Soto, Cinque, Stuckey, Jonathan, Burton, Dennis R., Koff, Wayne C., Connors, Mark, Kwon, Peter D.
Publicado 2014

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

por Wibmer, Constantinos Kurt, Gorman, Jason, Anthony, Colin S., Mkhize, Nonhlanhla N., Druz, Aliaksandr, York, Talita, Schmidt, Stephen D., Labuschagne, Phillip, Louder, Mark K., Bailer, Robert T., Abdool Karim, Salim S., Mascola, John R., Williamson, Carolyn, Moore, Penny L., Kwong, Peter D., Morris, Lynn
Publicado 2016

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

por Joyce, M. Gordon, Bao, Amy, Chen, Man, Georgiev, Ivelin S., Ou, Li, Bylund, Tatsiana, Druz, Aliaksandr, Kong, Wing-Pui, Peng, Dongjun, Rundlet, Emily J., Van Galen, Joseph G., Wang, Shuishu, Yang, Yongping, Zhang, Baoshan, Chuang, Gwo-Yu, McLellan, Jason S., Graham, Barney S., Mascola, John R., Kwong, Peter D.
Publicado 2019

Structure-Based Design of Head-Only Fusion Glycoprotein Immunogens for Respiratory Syncytial Virus

por Boyington, Jeffrey C., Joyce, M. Gordon, Sastry, Mallika, Stewart-Jones, Guillaume B. E., Chen, Man, Kong, Wing-Pui, Ngwuta, Joan O., Thomas, Paul V., Tsybovsky, Yaroslav, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Druz, Aliaksandr, Georgiev, Ivelin S., Ko, Kiyoon, Zhou, Tongqing, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado 2016

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

por Zhang, Baoshan, Chen, Lei, Silacci, Chiara, Thom, Michelle, Boyington, Jeffrey C., Druz, Aliaksandr, Joyce, M. Gordon, Guzman, Efrain, Kong, Wing- Pui, Lai, Yen-Ting, Stewart-Jones, Guillaume B. E., Tsybovsky, Yaroslav, Yang, Yongping, Zhou, Tongqing, Baxa, Ulrich, Mascola, John R., Corti, Davide, Lanzavecchia, Antonio, Taylor, Geraldine, Kwong, Peter D.
Publicado 2017

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

por Stewart-Jones, Guillaume B. E., Thomas, Paul V., Chen, Man, Druz, Aliaksandr, Joyce, M. Gordon, Kong, Wing-Pui, Sastry, Mallika, Soto, Cinque, Yang, Yongping, Zhang, Baoshan, Chen, Lei, Chuang, Gwo-Yu, Georgiev, Ivelin S., McLellan, Jason S., Srivatsan, Sanjay, Zhou, Tongqing, Baxa, Ulrich, Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado 2015

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

por Lai, Yen-Ting, Wang, Tao, O’Dell, Sijy, Louder, Mark K., Schön, Arne, Cheung, Crystal S. F., Chuang, Gwo-Yu, Druz, Aliaksandr, Lin, Bob, McKee, Krisha, Peng, Dongjun, Yang, Yongping, Zhang, Baoshan, Herschhorn, Alon, Sodroski, Joseph, Bailer, Robert T., Doria-Rose, Nicole A., Mascola, John R., Langley, David R., Kwong, Peter D.
Publicado 2019

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529

por Pancera, Marie, Lai, Yen-Ting, Bylund, Tatsiana, Druz, Aliaksandr, Narpala, Sandeep, O’Dell, Sijy, Schön, Arne, Bailer, Robert T., Chuang, Gwo-Yu, Geng, Hui, Louder, Mark K., Rawi, Reda, Soumana, Djade I., Finzi, Andrés, Herschhorn, Alon, Madani, Navid, Sodroski, Joseph, Freire, Ernesto, Langley, David R., Mascola, John R., McDermott, Adrian B., Kwong, Peter D.
Publicado 2017

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

por Wibmer, Constantinos Kurt, Gorman, Jason, Ozorowski, Gabriel, Bhiman, Jinal N., Sheward, Daniel J., Elliott, Debra H., Rouelle, Julie, Smira, Ashley, Joyce, M. Gordon, Ndabambi, Nonkululeko, Druz, Aliaksandr, Asokan, Mangai, Burton, Dennis R., Connors, Mark, Abdool Karim, Salim S., Mascola, John R., Robinson, James E., Ward, Andrew B., Williamson, Carolyn, Kwong, Peter D., Morris, Lynn, Moore, Penny L.
Publicado 2017

Structure and immune recognition of trimeric prefusion HIV-1 Env

por Pancera, Marie, Zhou, Tongqing, Druz, Aliaksandr, Georgiev, Ivelin S., Soto, Cinque, Gorman, Jason, Huang, Jinghe, Acharya, Priyamvada, Chuang, Gwo-Yu, Ofek, Gilad, Stewart-Jones, Guillaume B. E., Stuckey, Jonathan, Bailer, Robert T., Joyce, M. Gordon, Louder, Mark K., Tumba, Nancy, Yang, Yongping, Zhang, Baoshan, Cohen, Myron S., Haynes, Barton F., Mascola, John R., Morris, Lynn, Munro, James B., Blanchard, Scott C., Mothes, Walther, Connors, Mark, Kwong, Peter D.
Publicado 2014

Iterative structure-based improvement of a respiratory syncytial virus fusion glycoprotein vaccine

por Joyce, M. Gordon, Zhang, Baoshan, Ou, Li, Chen, Man, Chuang, Gwo-Yu, Druz, Aliaksandr, Kong, Wing-Pui, Lai, Yen-Ting, Rundlet, Emily J., Tsybovsky, Yaroslav, Yang, Yongping, Georgiev, Ivelin S., Guttman, Miklos, Lees, Christopher R., Pancera, Marie, Sastry, Mallika, Soto, Cinque, Stewart-Jones, Guillaume B.E., Thomas, Paul V., Van Galen, Joseph G., Baxa, Ulrich, Lee, Kelly K., Mascola, John R., Graham, Barney S., Kwong, Peter D.
Publicado 2016

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-120 interface

por Huang, Jinghe, Kang, Byong H., Pancera, Marie, Lee, Jeong Hyun, Tong, Tommy, Feng, Yu, Georgiev, Ivelin S., Chuang, Gwo-Yu, Druz, Aliaksandr, Doria-Rose, Nicole A., Laub, Leo, Sliepen, Kwinten, van Gils, Marit J., de la Peña, Alba Torrents, Derking, Ronald, Klasse, Per-Johan, Migueles, Stephen A., Bailer, Robert T., Alam, Munir, Pugach, Pavel, Haynes, Barton F., Wyatt, Richard T., Sanders, Rogier W., Binley, James M., Ward, Andrew B., Mascola, John R., Kwong, Peter D., Connors, Mark
Publicado 2014

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

por Ou, Li, Kong, Wing-Pui, Chuang, Gwo-Yu, Ghosh, Mridul, Gulla, Krishana, O’Dell, Sijy, Varriale, Joseph, Barefoot, Nathan, Changela, Anita, Chao, Cara W., Cheng, Cheng, Druz, Aliaksandr, Kong, Rui, McKee, Krisha, Rawi, Reda, Sarfo, Edward K., Schön, Arne, Shaddeau, Andrew, Tsybovsky, Yaroslav, Verardi, Raffaello, Wang, Shuishu, Wanninger, Timothy G., Xu, Kai, Yang, Gengcheng J., Zhang, Baoshan, Zhang, Yaqiu, Zhou, Tongqing, Arnold, Frank J., Doria-Rose, Nicole A., Lei, Q. Paula, Ryan, Edward T., Vann, Willie F., Mascola, John R., Kwong, Peter D.
Publicado 2020

Structures of HIV-1-Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

por Gorman, Jason, Soto, Cinque, Yang, Max M., Davenport, Thaddeus M., Guttman, Miklos, Bailer, Robert T., Chambers, Michael, Chuang, Gwo-Yu, DeKosky, Brandon J., Doria-Rose, Nicole A., Druz, Aliaksandr, Ernandes, Michael J., Georgiev, Ivelin S., Jarosinski, Marissa C., Joyce, M. Gordon, Lemmin, Thomas M., Leung, Sherman, Louder, Mark K., McDaniel, Jonathan R., Narpala, Sandeep, Pancera, Marie, Stuckey, Jonathan, Wu, Xueling, Yang, Yongping, Zhang, Baoshan, Zhou, Tongqing, Mullikin, James C., Baxa, Ulrich, Georgiou, George, McDermott, Adrian B., Bonsignori, Mattia, Haynes, Barton F., Moore, Penny L., Morris, Lynn, Lee, Kelly K., Shapiro, Lawrence, Mascola, John R., Kwong, Peter D.
Publicado 2015

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env

por Kwon, Young Do, Pancera, Marie, Acharya, Priyamvada, Georgiev, Ivelin S., Crooks, Emma T., Gorman, Jason, Joyce, M. Gordon, Guttman, Miklos, Ma, Xiaochu, Narpala, Sandeep, Soto, Cinque, Terry, Daniel S., Yang, Yongping, Zhou, Tongqing, Ahlsen, Goran, Bailer, Robert T., Chambers, Michael, Chuang, Gwo-Yu, Doria-Rose, Nicole A., Druz, Aliaksandr, Hallen, Mark A., Harned, Adam, Kirys, Tatsiana, Louder, Mark K., O’Dell, Sijy, Ofek, Gilad, Osawa, Keiko, Prabhakaran, Madhu, Sastry, Mallika, Stewart-Jones, Guillaume B.E., Stuckey, Jonathan, Thomas, Paul V., Tittley, Tishina, Williams, Constance, Zhang, Baoshan, Zhao, Hong, Zhou, Zhou, Donald, Bruce R., Lee, Lawrence K., Zolla-Pazner, Susan, Baxa, Ulrich, Schön, Arne, Freire, Ernesto, Shapiro, Lawrence, Lee, Kelly K., Arthos, James, Munro, James B., Blanchard, Scott C., Mothes, Walther, Binley, James M., McDermott, Adrian B., Mascola, John R., Kwong, Peter D.
Publicado 2015

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

por Xu, Kai, Acharya, Priyamvada, Kong, Rui, Cheng, Cheng, Chuang, Gwo-Yu, Liu, Kevin, Louder, Mark K., O’Dell, Sijy, Rawi, Reda, Sastry, Mallika, Shen, Chen-Hsiang, Zhang, Baoshan, Zhou, Tongqing, Asokan, Mangaiarkarasi, Bailer, Robert T., Chambers, Michael, Chen, Xuejun, Choi, Chang W., Dandey, Venkata P., Doria-Rose, Nicole A., Druz, Aliaksandr, Eng, Edward T., Farney, Katie, Foulds, Kathryn E., Geng, Hui, Georgiev, Ivelin S., Gorman, Jason, Hill, Kurt R., Jafari, Alexander J., Kwon, Young D., Lai, Yen-Ting, Lemmin, Thomas, McKee, Krisha, Ohr, Tiffany Y., Ou, Li, Peng, Dongjun, Rowshan, Ariana P., Sheng, Zizhang, Todd, John-Paul, Tsybovsky, Yaroslav, Viox, Elise G., Wang, Yiran, Wei, Hui, Yang, Yongping, Zhou, Amy F., Chen, Rui, Yang, Lu, Scorpio, Diana G., McDermott, Adrian B., Shapiro, Lawrence, Carragher, Bridget, Potter, Clinton S., Mascola, John R., Kwong, Peter D.
Publicado 2018