“RHAMM knockout” mice express a truncated RHAMM protein that promotes pancreatic cancer progression with dysfunctional p53

por Chen, Xiang, Du, Yi-Chieh Nancy
Publicado 2022

Activation of PyMT in β Cells Induces Irreversible Hyperplasia, but Oncogene-Dependent Acinar Cell Carcinomas When Activated in Pancreatic Progenitors

por Du, Yi-Chieh Nancy, Klimstra, David S., Varmus, Harold
Publicado 2009

Immunohistochemical analysis of RHAMM expression in normal and neoplastic human tissues: a cell cycle protein with distinctive expression in mitotic cells and testicular germ cells

por Chen, Yao-Tseng, Chen, Zhengming, Du, Yi-Chieh Nancy
Publicado 2018

p53 and p16(Ink4a)/p19(Arf) Loss Promotes Different Pancreatic Tumor Types from PyMT-Expressing Progenitor Cells()()

por Azzopardi, Stephanie, Pang, Sharon, Klimstra, David S., Du, Yi-Chieh Nancy
Publicado 2016

Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion

por Du, Yi-Chieh Nancy, Lewis, Brian C, Hanahan, Douglas, Varmus, Harold
Publicado 2007

(-)-Oleocanthal and (-)-oleocanthal-rich olive oils induce lysosomal membrane permeabilization in cancer cells

por Goren, Limor, Zhang, George, Kaushik, Susmita, Breslin, Paul A. S., Du, Yi-Chieh Nancy, Foster, David A.
Publicado 2019

Alleles of Insm1 determine whether RIP1-Tag2 mice produce insulinomas or nonfunctioning pancreatic neuroendocrine tumors

por Kobayashi, Shinta, Contractor, Tanupriya, Vosburgh, Evan, Du, Yi-Chieh Nancy, Tang, Laura H., Clausen, Richard, Harris, Chris R.
Publicado 2019

Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma

por Wang, Dunrui, Narula, Navneet, Azzopardi, Stephanie, Smith, Roger S., Nasar, Abu, Altorki, Nasser K., Mittal, Vivek, Somwar, Romel, Stiles, Brendon M., Du, Yi-Chieh Nancy
Publicado 2016

Functional impact of cancer patient‐associated Bcl‐xL mutations

por Zhang, Tiantian, Na, Joseph HyungJoon, Li, Samantha, Chen, Zhengming, Zhang, George, Pang, Sharon, Daniyan, Anthony F., Li, Yi, Shi, Lei, Du, Yi‐Chieh Nancy
Publicado 2020

Bcl-xL promotes metastasis independent of its anti-apoptotic activity

por Choi, Soyoung, Chen, Zhengming, Tang, Laura H., Fang, Yuanzhang, Shin, Sandra J., Panarelli, Nicole C., Chen, Yao-Tseng, Li, Yi, Jiang, Xuejun, Du, Yi-Chieh Nancy
Publicado 2016

RHAMM(B)-mediated bifunctional nanotherapy targeting Bcl-xL and mitochondria for pancreatic neuroendocrine tumor treatment

por Chen, Xiang, Lee, Seung Koo, Song, Mei, Zhang, Tiantian, Han, Myung Shin, Chen, Yao-Tseng, Chen, Zhengming, Ma, Xiaojing, Tung, Ching-Hsuan, Du, Yi-Chieh Nancy
Publicado 2021

Function and clinical relevance of RHAMM isoforms in pancreatic tumor progression

por Choi, Soyoung, Wang, Dunrui, Chen, Xiang, Tang, Laura H., Verma, Akanksha, Chen, Zhengming, Kim, Bu Jung, Selesner, Leigh, Robzyk, Kenneth, Zhang, George, Pang, Sharon, Han, Teng, Chan, Chang S., Fahey, Thomas J., Elemento, Olivier, Du, Yi-Chieh Nancy
Publicado 2019

Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

por Zhang, Tiantian, Li, Sha, Tan, Yingcai Adrian, Na, Joseph HyungJoon, Chen, Zhengming, Damle, Priyadarshan, Chen, Xiang, Choi, Soyoung, Mishra, Bikash, Wang, Dunrui, Grossman, Steven R., Jiang, Xuejun, Li, Yi, Chen, Yao-Tseng, Xiang, Jenny Z., Du, Yi-Chieh Nancy
Publicado 2023

Loss of MEN1 activates DNMT1 implicating DNA hypermethylation as a driver of MEN1 tumorigenesis

por Yuan, Ziqiang, Claros, Carmen Sánchez, Suzuki, Masako, Maggi, Elaine C., Kaner, Justin D., Kinstlinger, Noah, Gorecka, Jolanta, Quinn, Thomas J., Geha, Rula, Corn, Amanda, Pastoriza, Jessica, Jing, Qiang, Adem, Asha, Wu, Hao, Alemu, Girum, Du, Yi-Chieh, Zheng, Deyou, Greally, John M., Libutti, Steven K.
Publicado 2016

Metastatic pancreatic neuroendocrine tumors feature elevated T cell infiltration

por Greenberg, Jacques, Limberg, Jessica, Verma, Akanksha, Kim, David, Chen, Xiang, Lee, Yeon J., Moore, Maureen D., Ullmann, Timothy M., Thiesmeyer, Jessica W., Loewenstein, Zachary, Chen, Kevin J., Egan, Caitlin E., Stefanova, Dessislava, Bareja, Rohan, Zarnegar, Rasa, Finnerty, Brendan M., Scognamiglio, Theresa, Du, Yi-Chieh Nancy, Elemento, Olivier, Fahey, Thomas J., Min, Irene M.
Publicado 2022