How pH Modulates the Reactivity and Selectivity of a Siderophore-Associated Flavin Monooxygenase

por Frederick, Rosanne E., Ojha, Sunil, Lamb, Audrey, DuBois, Jennifer L.
Publicado 2014

Bacteroides thetaiotaomicron, a Model Gastrointestinal Tract Species, Prefers Heme as an Iron Source, Yields Protoporphyrin IX as a Product, and Acts as a Heme Reservoir

por Meslé, Margaux M., Gray, Chase R., Dlakić, Mensur, DuBois, Jennifer L.
Publicado 2023

A catalytic dyad modulates conformational change in the CO(2)-fixing flavoenzyme 2-ketopropyl coenzyme M oxidoreductase/carboxylase

por Mattice, Jenna R., Shisler, Krista A., DuBois, Jennifer L., Peters, John W., Bothner, Brian
Publicado 2022

Pathways of Iron and Sulfur Acquisition, Cofactor Assembly, Destination, and Storage in Diverse Archaeal Methanogens and Alkanotrophs

por Johnson, Christina, England, Alexis, Munro-Ehrlich, Mason, Colman, Daniel R., DuBois, Jennifer L., Boyd, Eric S.
Publicado 2021

Dynamic Gut Microbiome Changes in Response to Low-Iron Challenge

por Coe, Genevieve L., Pinkham, Nicholas V., Celis, Arianna I., Johnson, Christina, DuBois, Jennifer L., Walk, Seth T.
Publicado 2021

Staphylococcus aureus HemX Modulates Glutamyl-tRNA Reductase Abundance To Regulate Heme Biosynthesis

por Choby, Jacob E., Grunenwald, Caroline M., Celis, Arianna I., Gerdes, Svetlana Y., DuBois, Jennifer L., Skaar, Eric P.
Publicado 2018

The unique Phe–His dyad of 2-ketopropyl coenzyme M oxidoreductase/carboxylase selectively promotes carboxylation and S–C bond cleavage

por Prussia, Gregory A., Shisler, Krista A., Zadvornyy, Oleg A., Streit, Bennett R., DuBois, Jennifer L., Peters, John W.
Publicado 2021

A flexible kinetic assay efficiently sorts prospective biocatalysts for PET plastic subunit hydrolysis

por Lusty Beech, Jessica, Clare, Rita, Kincannon, William M., Erickson, Erika, McGeehan, John E., Beckham, Gregg T., DuBois, Jennifer L.
Publicado 2022

Biochemical and structural characterization of an aromatic ring–hydroxylating dioxygenase for terephthalic acid catabolism

por Kincannon, William M., Zahn, Michael, Clare, Rita, Lusty Beech, Jessica, Romberg, Ari, Larson, James, Bothner, Brian, Beckham, Gregg T., McGeehan, John E., DuBois, Jennifer L.
Publicado 2022

A Dimeric Chlorite Dismutase Exhibits O(2)-Generating Activity and Acts as a Chlorite Antioxidant in Klebsiella pneumoniae MGH 78578

por Celis, Arianna I., Geeraerts, Zachary, Ngmenterebo, David, Machovina, Melodie M., Kurker, Richard C., Rajakumar, Kumar, Ivancich, Anabella, Rodgers, Kenton R., Lukat-Rodgers, Gudrun S., DuBois, Jennifer L.
Publicado 2014

Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation

por Mus, Florence, Eilers, Brian J., Alleman, Alexander B., Kabasakal, Burak V., Wells, Jennifer N., Murray, James W., Nocek, Boguslaw P., DuBois, Jennifer L., Peters, John W.
Publicado 2017

Heme sensing and detoxification by HatRT contributes to pathogenesis during Clostridium difficile infection

por Knippel, Reece J., Zackular, Joseph P., Moore, Jessica L., Celis, Arianna I., Weiss, Andy, Washington, M. Kay, DuBois, Jennifer L., Caprioli, Richard M., Skaar, Eric P.
Publicado 2018

A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion

por Mallinson, Sam J. B., Machovina, Melodie M., Silveira, Rodrigo L., Garcia-Borràs, Marc, Gallup, Nathan, Johnson, Christopher W., Allen, Mark D., Skaf, Munir S., Crowley, Michael F., Neidle, Ellen L., Houk, Kendall N., Beckham, Gregg T., DuBois, Jennifer L., McGeehan, John E.
Publicado 2018

The pathway for coenzyme M biosynthesis in bacteria

por Wu, Hsin-Hua, Pun, Michael D., Wise, Courtney E., Streit, Bennett R., Mus, Florence, Berim, Anna, Kincannon, William M., Islam, Abdullah, Partovi, Sarah E., Gang, David R., DuBois, Jennifer L., Lubner, Carolyn E., Berkman, Clifford E., Lange, B. Markus, Peters, John W.
Publicado 2022

Engineering a Cytochrome P450 for Demethylation of Lignin-Derived Aromatic Aldehydes

por Ellis, Emerald S., Hinchen, Daniel J., Bleem, Alissa, Bu, Lintao, Mallinson, Sam J. B., Allen, Mark D., Streit, Bennett R., Machovina, Melodie M., Doolin, Quinlan V., Michener, William E., Johnson, Christopher W., Knott, Brandon C., Beckham, Gregg T., McGeehan, John E., DuBois, Jennifer L.
Publicado 2021

Enabling microbial syringol conversion through structure-guided protein engineering

por Machovina, Melodie M., Mallinson, Sam J. B., Knott, Brandon C., Meyers, Alexander W., Garcia-Borràs, Marc, Bu, Lintao, Gado, Japheth E., Oliver, April, Schmidt, Graham P., Hinchen, Daniel J., Crowley, Michael F., Johnson, Christopher W., Neidle, Ellen L., Payne, Christina M., Houk, Kendall N., Beckham, Gregg T., McGeehan, John E., DuBois, Jennifer L.
Publicado 2019

Sourcing thermotolerant poly(ethylene terephthalate) hydrolase scaffolds from natural diversity

por Erickson, Erika, Gado, Japheth E., Avilán, Luisana, Bratti, Felicia, Brizendine, Richard K., Cox, Paul A., Gill, Raj, Graham, Rosie, Kim, Dong-Jin, König, Gerhard, Michener, William E., Poudel, Saroj, Ramirez, Kelsey J., Shakespeare, Thomas J., Zahn, Michael, Boyd, Eric S., Payne, Christina M., DuBois, Jennifer L., Pickford, Andrew R., Beckham, Gregg T., McGeehan, John E.
Publicado 2022