CRISPR/Cas9 disruption of EpCAM Exon 2 results in cell-surface expression of a truncated protein targeted by an EpCAM specific T cell engager

por Bagheri, Andisheh, Culp, Patricia A., DuBridge, Robert B., Chen, Tseng-hui Timothy
Publicado 2022

A function blocking anti-mouse integrin α5β1 antibody inhibits angiogenesis and impedes tumor growth in vivo

por Bhaskar, Vinay, Zhang, Dong, Fox, Melvin, Seto, Pui, Wong, Melanie HL, Wales, Pauline E, Powers, David, Chao, Debra T, DuBridge, Robert B, Ramakrishnan, Vanitha
Publicado 2007

Deep mutational scanning of an antibody against epidermal growth factor receptor using mammalian cell display and massively parallel pyrosequencing

por Forsyth, Charles M., Juan, Veronica, Akamatsu, Yoshiko, DuBridge, Robert B., Doan, Minhtam, Ivanov, Alexander V., Ma, Zhiyuan, Polakoff, Dixie, Razo, Jennifer, Wilson, Keith, Powers, David B.
Publicado 2013

Regression of EGFR positive established solid tumors in mice with the conditionally active T cell engager TAK-186

por Dettling, Danielle E, Kwok, Eilene, Quach, Lucy, Datt, Aakash, Degenhardt, Jeremiah D, Panchal, Anand, Seto, Pui, Krakow, Jessica L, Wall, Russell, Hillier, Brian J, Zhu, Ying, Vinogradova, Maia, DuBridge, Robert B, May, Chad
Publicado 2022

COBRA™: a highly potent conditionally active T cell engager engineered for the treatment of solid tumors

por Panchal, Anand, Seto, Pui, Wall, Russell, Hillier, Brian J., Zhu, Ying, Krakow, Jessica, Datt, Aakash, Pongo, Elizabeth, Bagheri, Andisheh, Chen, Tseng-Hui T., Degenhardt, Jeremiah D., Culp, Patricia A., Dettling, Danielle E., Vinogradova, Maia V., May, Chad, DuBridge, Robert B.
Publicado 2020