Antimetabolite TTL-315 selectively kills glucose-deprived cancer cells and enhances responses to cytotoxic chemotherapy in preclinical models of cancer

por DuHadaway, James, Prendergast, George C.
Publicado 2016

IDO1 is an Integral Mediator of Inflammatory Neovascularization

por Mondal, Arpita, Smith, Courtney, DuHadaway, James B., Sutanto-Ward, Erika, Prendergast, George C., Bravo-Nuevo, Arturo, Muller, Alexander J.
Publicado 2016

RhoB blockade selectively inhibits autoantibody production in autoimmune models of rheumatoid arthritis and lupus

por Mandik-Nayak, Laura, DuHadaway, James B., Mulgrew, Jennifer, Pigott, Elizabeth, Manley, Kaylend, Sedano, Summer, Prendergast, George C., Laury-Kleintop, Lisa D.
Publicado 2017

IDO inhibits a tryptophan sufficiency signal that stimulates mTOR: A novel IDO effector pathway targeted by D-1-methyl-tryptophan

por Metz, Richard, Rust, Sonja, DuHadaway, James B., Mautino, Mario R., Munn, David H., Vahanian, Nicholas N., Link, Charles J., Prendergast, George C.
Publicado 2012

Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy

por Huang, Yu-Hung, Peng, Weidan, Furuuchi, Narumi, DuHadaway, James B., Jimbo, Masaya, Pirritano, Andrea, Dunton, Charles J., Daum, Gary S., Leiby, Benjamin E., Brody, Jonathan R., Sawicki, Janet A.
Publicado 2016

Differential Roles of IDO1 and IDO2 in T and B Cell Inflammatory Immune Responses

por Merlo, Lauren M. F., DuHadaway, James B., Montgomery, James D., Peng, Wei-Dan, Murray, Peter J., Prendergast, George C., Caton, Andrew J., Muller, Alexander J., Mandik-Nayak, Laura
Publicado 2020

Peptide vaccination directed against IDO1-expressing immune cells elicits CD8(+) and CD4(+) T-cell-mediated antitumor immunity and enhanced anti-PD1 responses

por Dey, Souvik, Sutanto-Ward, Erika, Kopp, Katharina L, DuHadaway, James, Mondal, Arpita, Ghaban, Dema, Lecoq, Inés, Zocca, Mai-Britt, Merlo, Lauren M F, Mandik-Nayak, Laura, Andersen, Mads Hald, Pedersen, Ayako Wakatsuki, Muller, Alexander J
Publicado 2020

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses

por Li, Zhiping, Jiao, Xuanmao, Robertson, A. Gordon, Di Sante, Gabriele, Ashton, Anthony W., DiRocco, Agnese, Wang, Min, Zhao, Jun, Addya, Sankar, Wang, Chenguang, McCue, Peter A., South, Andrew P., Cordon-Cardo, Carlos, Liu, Runzhi, Patel, Kishan, Hamid, Rasha, Parmar, Jorim, DuHadaway, James B., Jones, Steven J. M., Casimiro, Mathew C., Schultz, Nikolaus, Kossenkov, Andrew, Phoon, Lai Yee, Chen, Hao, Lan, Li, Sun, Yunguang, Iczkowski, Kenneth A., Rui, Hallgeir, Pestell, Richard G.
Publicado 2023

The DACH1 gene is frequently deleted in prostate cancer, restrains prostatic intraepithelial neoplasia, decreases DNA damage repair, and predicts therapy responses

por Li, Zhiping, Jiao, Xuanmao, Robertson, A. Gordon, Sante, Gabriele Di, Ashton, Anthony W., DiRocco, Agnese, Wang, Min, Zhao, Jun, Addya, Sankar, Wang, Chenguang, McCue, Peter A., South, Andrew P., Cordon-Cardo, Carlos, Liu, Runzhi, Patel, Kishan, Hamid, Rasha, Parmar, Jorim, DuHadaway, James B., Jones, Steven J., Casimiro, Mathew C., Schultz, Nikolaus, Kossenkov, Andrew, Phoon, Lai Yee, Chen, Hao, Lan, Li, Sun, Yunguang, Iczkowski, Kenneth A., Rui, Hallgeir, Pestell, Richard G.
Publicado 2023