The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma

por He, Di, Xu, Qin, Yan, Ming, Zhang, Ping, Zhou, Xiaojian, Zhang, Zhiyuan, Duan, Wenhu, Zhong, Laiping, Ye, Dongxia, Chen, Wantao
Publicado 2009

Simm530, a novel and highly selective c-Met inhibitor, blocks c-Met-stimulated signaling and neoplastic activities

por Wang, Ying, Zhan, Zhengsheng, Jiang, Xifei, Peng, Xia, Shen, Yanyan, Chen, Fang, Ji, Yinchun, Liu, Weiren, Shi, Yinghong, Duan, Wenhu, Ding, Jian, Ai, Jing, Geng, Meiyu
Publicado 2016

Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4α

por Zheng, Bai-Nan, Ding, Chen-Hong, Chen, Shi-Jie, Zhu, Kongkai, Shao, Jingwei, Feng, Jifeng, Xu, Wen-Ping, Cai, Ling-Yan, Zhu, Chang-Peng, Duan, Wenhu, Ding, Jin, Zhang, Xin, Luo, Cheng, Xie, Wei-Fen
Publicado 2019

Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation

por Xie, Zuoquan, Wang, Zhen, Fan, Fengying, Zhou, Jinpei, Hu, Zhaoxue, Wang, Qingxia, Wang, Xiyuan, Zeng, Qingzhong, Zhang, Yan, Qiu, Jiaxuan, Zhou, Xiaoqian, Xu, Hui, Bai, Hudagula, Zhan, Zhengsheng, Ding, Jian, Zhang, Huibin, Duan, Wenhu, Yu, Xuekui, Geng, Meiyu
Publicado 2022

Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood–brain barrier and exhibits potent activity against glioblastoma

por Liu, Yingqiang, Zhan, Zhengsheng, Kang, Zhuang, Li, Mengyuan, Lv, Yongcong, Li, Shenglan, Tong, Linjiang, Feng, Fang, Li, Yan, Zhang, Mengge, Xue, Yaping, Chen, Yi, Zhang, Tao, Song, Peiran, Su, Yi, Shen, Yanyan, Sun, Yiming, Yang, Xinying, Chen, Yi, Yao, Shanyan, Yang, Hanyu, Wang, Caixia, Geng, Meiyu, Li, Wenbin, Duan, Wenhu, Xie, Hua, Ding, Jian
Publicado 2023