Ditching candidate gene association studies: lessons from psychiatric genetics

por Duarte, Rodrigo R.R., Brentani, Helena, Powell, Timothy R.
Publicado 2021

Prolactin, Estradiol and Testosterone Differentially Impact Human Hippocampal Neurogenesis in an In Vitro Model

por Smeeth, Demelza M., Kourouzidou, Ioanna, Duarte, Rodrigo R.R., Powell, Timothy R., Thuret, Sandrine
Publicado 2021

Transcriptome-wide association study of HIV-1 acquisition identifies HERC1 as a susceptibility gene

por Duarte, Rodrigo R.R., Pain, Oliver, Furler, Robert L., Nixon, Douglas F., Powell, Timothy R.
Publicado 2022

Genome‐wide significant schizophrenia risk variation on chromosome 10q24 is associated with altered cis‐regulation of BORCS7, AS3MT, and NT5C2 in the human brain

por Duarte, Rodrigo R. R., Troakes, Claire, Nolan, Matthew, Srivastava, Deepak P., Murray, Robin M., Bray, Nicholas J.
Publicado 2016

Genetic risk for severe COVID‐19 correlates with lower inflammatory marker levels in a SARS‐CoV‐2‐negative cohort

por Powell, Timothy R, Hotopf, Matthew, Hatch, Stephani L, Breen, Gerome, Duarte, Rodrigo R R, Nixon, Douglas F
Publicado 2021

The polygenic nature of telomere length and the anti-ageing properties of lithium

por Coutts, Fiona, Palmos, Alish B., Duarte, Rodrigo R. R., de Jong, Simone, Lewis, Cathryn M., Dima, Danai, Powell, Timothy R.
Publicado 2018

Telomere length and human hippocampal neurogenesis

por Palmos, Alish B., Duarte, Rodrigo R. R., Smeeth, Demelza M., Hedges, Erin C., Nixon, Douglas F., Thuret, Sandrine, Powell, Timothy R.
Publicado 2020

Lithium treatment and human hippocampal neurogenesis

por Palmos, Alish B., Duarte, Rodrigo R. R., Smeeth, Demelza M., Hedges, Erin C., Nixon, Douglas F., Thuret, Sandrine, Powell, Timothy R.
Publicado 2021

SARS-CoV-2 infection mediates differential expression of human endogenous retroviruses and long interspersed nuclear elements

por Marston, Jez L., Greenig, Matthew, Singh, Manvendra, Bendall, Matthew L., Duarte, Rodrigo R.R., Feschotte, Cédric, Iñiguez, Luis P., Nixon, Douglas F.
Publicado 2021

Neuroligin-3 and neuroligin-4X form nanoscopic clusters and regulate growth cone organization and size

por Gatford, Nicholas J F, Deans, P J Michael, Duarte, Rodrigo R R, Chennell, George, Sellers, Katherine J, Raval, Pooja, Srivastava, Deepak P
Publicado 2021

Inter-individual variation in genes governing human hippocampal progenitor differentiation in vitro is associated with hippocampal volume in adulthood

por Powell, Timothy R., Murphy, Tytus, Lee, Sang H., Duarte, Rodrigo R. R., Lee, Hyun Ah, Smeeth, Demelza, Price, Jack, Breen, Gerome, Thuret, Sandrine
Publicado 2017

The behavioral, cellular and immune mediators of HIV-1 acquisition: New insights from population genetics

por Powell, Timothy R., Duarte, Rodrigo R. R., Hotopf, Matthew, Hatch, Stephani L., de Mulder Rougvie, Miguel, Breen, Gerome D., Lewis, Cathryn M., Nixon, Douglas F.
Publicado 2020

Identifying FDA-approved drugs with multimodal properties against COVID-19 using a data-driven approach and a lung organoid model of SARS-CoV-2 entry

por Duarte, Rodrigo R. R., Copertino, Dennis C., Iñiguez, Luis P., Marston, Jez L., Bram, Yaron, Han, Yuling, Schwartz, Robert E., Chen, Shuibing, Nixon, Douglas F., Powell, Timothy R.
Publicado 2021

Acute IL-6 exposure triggers canonical IL6Ra signaling in hiPSC microglia, but not neural progenitor cells

por Couch, Amalie C.M., Solomon, Shiden, Duarte, Rodrigo R.R., Marrocu, Alessia, Sun, Yiqing, Sichlinger, Laura, Matuleviciute, Rugile, Polit, Lucia Dutan, Hanger, Bjørn, Brown, Amelia, Kordasti, Shahram, Srivastava, Deepak P., Vernon, Anthony C.
Publicado 2023

Psychosis Risk Candidate ZNF804A Localizes to Synapses and Regulates Neurite Formation and Dendritic Spine Structure

por Deans, P.J. Michael, Raval, Pooja, Sellers, Katherine J., Gatford, Nicholas J.F., Halai, Sanjay, Duarte, Rodrigo R.R., Shum, Carole, Warre-Cornish, Katherine, Kaplun, Victoria E., Cocks, Graham, Hill, Matthew, Bray, Nicholas J., Price, Jack, Srivastava, Deepak P.
Publicado 2017

Interferon-γ signaling in human iPSC–derived neurons recapitulates neurodevelopmental disorder phenotypes

por Warre-Cornish, Katherine, Perfect, Leo, Nagy, Roland, Duarte, Rodrigo R. R., Reid, Matthew J., Raval, Pooja, Mueller, Annett, Evans, Amanda L., Couch, Amalie, Ghevaert, Cédric, McAlonan, Grainne, Loth, Eva, Murphy, Declan, Powell, Timothy R., Vernon, Anthony C., Srivastava, Deepak P., Price, Jack
Publicado 2020

The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells

por Duarte, Rodrigo R.R., Bachtel, Nathaniel D., Côtel, Marie-Caroline, Lee, Sang H., Selvackadunco, Sashika, Watson, Iain A., Hovsepian, Gary A., Troakes, Claire, Breen, Gerome D., Nixon, Douglas F., Murray, Robin M., Bray, Nicholas J., Eleftherianos, Ioannis, Vernon, Anthony C., Powell, Timothy R., Srivastava, Deepak P.
Publicado 2019

Attenuated transcriptional response to pro-inflammatory cytokines in schizophrenia hiPSC-derived neural progenitor cells

por Bhat, Anjali, Irizar, Haritz, Couch, Amalie C.M., Raval, Pooja, Duarte, Rodrigo R.R., Dutan Polit, Lucia, Hanger, Bjorn, Powell, Timothy, Deans, P.J. Michael, Shum, Carole, Nagy, Roland, McAlonan, Grainne, Iyegbe, Conrad O., Price, Jack, Bramon, Elvira, Bhattacharyya, Sagnik, Vernon, Anthony C., Srivastava, Deepak P.
Publicado 2022