Non-Surgical Cancer Risk Reduction in BRCA1 Mutation Carriers: Disabling the Remote Control

por Widschwendter, Martin, Dubeau, Louis
Publicado 2020

A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function

por Yuan, Bin, Yang, Jing, Dubeau, Louis, Hu, Yanfen, Li, Rong
Publicado 2021

GRP78 Inhibitor YUM70 Suppresses SARS-CoV-2 Viral Entry, Spike Protein Production and Ameliorates Lung Damage

por Ha, Dat P., Shin, Woo-Jin, Hernandez, Juan Carlos, Neamati, Nouri, Dubeau, Louis, Machida, Keigo, Lee, Amy S.
Publicado 2023

A Mouse Model That Reproduces the Developmental Pathways and Site Specificity of the Cancers Associated With the Human BRCA1 Mutation Carrier State

por Liu, Ying, Yen, Hai-Yun, Austria, Theresa, Pettersson, Jonas, Peti-Peterdi, Janos, Maxson, Robert, Widschwendter, Martin, Dubeau, Louis
Publicado 2015

Glucose-regulated protein 94 deficiency induces squamous cell metaplasia and suppresses PTEN-null driven endometrial epithelial tumor development

por Shen, Jieli, Yao, Lijing, Lin, Yvonne G., DeMayo, Francesco J., Lydon, John P., Dubeau, Louis, Lee, Amy S.
Publicado 2016

Maf1 Is a Novel Target of PTEN and PI3K Signaling That Negatively Regulates Oncogenesis and Lipid Metabolism

por Palian, Beth M., Rohira, Aarti D., Johnson, Sandra A. S., He, Lina, Zheng, Ni, Dubeau, Louis, Stiles, Bangyan L., Johnson, Deborah L.
Publicado 2014

POTENTIAL CONSEQUENCES OF THE BRCA1 MUTATION CARRIER STATE ON ESTROGEN RESPONSIVE ORGANS

por Yen, Hai-Yun, Gabet, Yankel, Liu, Ying, Martin, Anthony, Wu, Nancy L, Pike, Malcolm C, Frenkel, Baruch, Maxson, Robert, Dubeau, Louis
Publicado 2012

Epigenetic regulation of AXL and risk of childhood asthma symptoms

por Gao, Lu, Millstein, Joshua, Siegmund, Kimberly D., Dubeau, Louis, Maguire, Rachel, Gilliland, Frank D., Murphy, Susan K., Hoyo, Cathrine, Breton, Carrie V.
Publicado 2017

Essential role of the unfolded protein response regulator GRP78/BiP in protection from neuronal apoptosis

por Wang, Miao, Ye, Risheng, Barron, Ernesto, Baumeister, Peter, Mao, Changhui, Luo, Shengzhan, Fu, Yong, Luo, Biquan, Dubeau, Louis, Hinton, David R., Lee, Amy S.
Publicado 2009

Effects of Prolonged GRP78 Haploinsufficiency on Organ Homeostasis, Behavior, Cancer and Chemotoxic Resistance in Aged Mice

por Lee, Amy S., Brandhorst, Sebastian, Rangel, Daisy F., Navarrete, Gerardo, Cohen, Pinchas, Longo, Valter D., Chen, Jeannie, Groshen, Susan, Morgan, Todd E., Dubeau, Louis
Publicado 2017

Expression of protein disulfide isomerase family members correlates with tumor progression and patient survival in ovarian cancer

por Samanta, Soma, Tamura, Shuzo, Dubeau, Louis, Mhawech-Fauceglia, Paulette, Miyagi, Yohei, Kato, Hisamori, Lieberman, Rich, Buckanovich, Ronald J., Lin, Yvonne G., Neamati, Nouri
Publicado 2017

Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma

por Samanta, Soma, Tamura, Shuzo, Dubeau, Louis, Mhawech-Fauceglia, Paulette, Miyagi, Yohei, Kato, Hisamori, Lieberman, Rich, Buckanovich, Ronald J., Lin, Yvonne G., Neamati, Nouri
Publicado 2020

Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution

por Bartlett, Thomas E., Chindera, Kantaraja, McDermott, Jacqueline, Breeze, Charles E., Cooke, William R., Jones, Allison, Reisel, Daniel, Karegodar, Smita T., Arora, Rupali, Beck, Stephan, Menon, Usha, Dubeau, Louis, Widschwendter, Martin
Publicado 2016

Self-reported prenatal tobacco smoke exposure, AXL gene-body methylation, and childhood asthma phenotypes

por Gao, Lu, Liu, Xiaochen, Millstein, Joshua, Siegmund, Kimberly D., Dubeau, Louis, Maguire, Rachel L., (Jim) Zhang, Junfeng, Fuemmeler, Bernard F., Kollins, Scott H., Hoyo, Cathrine, Murphy, Susan K., Breton, Carrie V.
Publicado 2018

Brca1 Mutations Enhance Mouse Reproductive Functions by Increasing Responsiveness to Male-Derived Scent

por Liu, Ying, Pike, Malcolm C., Wu, Nancy, Lin, Yvonne G., Mucowski, Sara, Punj, Vasu, Tang, Yuan, Yen, Hai-Yun, Stanczyk, Frank Z., Enbom, Elena, Austria, Theresa, Widschwendter, Martin, Maxson, Robert, Dubeau, Louis
Publicado 2015

Osteoprotegerin (OPG), The Endogenous Inhibitor of Receptor Activator of NF-κB Ligand (RANKL), is Dysregulated in BRCA Mutation Carriers

por Widschwendter, Martin, Burnell, Matthew, Fraser, Lindsay, Rosenthal, Adam N., Philpott, Sue, Reisel, Daniel, Dubeau, Louis, Cline, Mark, Pan, Yang, Yi, Ping-Cheng, Gareth Evans, D., Jacobs, Ian J., Menon, Usha, Wood, Charles E., Dougall, William C.
Publicado 2015

Genome-Scale Screen for DNA Methylation-Based Detection Markers for Ovarian Cancer

por Campan, Mihaela, Moffitt, Melissa, Houshdaran, Sahar, Shen, Hui, Widschwendter, Martin, Daxenbichler, Günter, Long, Tiffany, Marth, Christian, Laird-Offringa, Ite A., Press, Michael F., Dubeau, Louis, Siegmund, Kimberly D., Wu, Anna H., Groshen, Susan, Chandavarkar, Uma, Roman, Lynda D., Berchuck, Andrew, Pearce, Celeste L., Laird, Peter W.
Publicado 2011

Aberrant regulation of RANKL/OPG in women at high risk of developing breast cancer

por Kiechl, Stefan, Schramek, Daniel, Widschwendter, Martin, Fourkala, Evangelia-Ourania, Zaikin, Alexey, Jones, Allison, Jaeger, Bernadette, Rack, Brigitte, Janni, Wolfgang, Scholz, Christoph, Willeit, Johann, Weger, Siegfried, Mayr, Agnes, Teschendorff, Andrew, Rosenthal, Adam, Fraser, Lindsay, Philpott, Susan, Dubeau, Louis, Keshtgar, Mohammed, Roylance, Rebecca, Jacobs, Ian J., Menon, Usha, Schett, Georg, Penninger, Josef M.
Publicado 2016

Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women

por Bartlett, Thomas E., Evans, Iona, Jones, Allison, Barrett, James E., Haran, Shaun, Reisel, Daniel, Papaikonomou, Kiriaki, Jones, Louise, Herzog, Chiara, Pashayan, Nora, Simões, Bruno M., Clarke, Robert B., Evans, D. Gareth, Ghezelayagh, Talayeh S., Ponandai-Srinivasan, Sakthivignesh, Boggavarapu, Nageswara R., Lalitkumar, Parameswaran G., Howell, Sacha J., Risques, Rosa Ana, Rådestad, Angelique Flöter, Dubeau, Louis, Gemzell-Danielsson, Kristina, Widschwendter, Martin
Publicado 2022

Correction: Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women

por Bartlett, Thomas E., Evans, Iona, Jones, Allison, Barrett, James E., Haran, Shaun, Reisel, Daniel, Papaikonomou, Kiriaki, Jones, Louise, Herzog, Chiara, Pashayan, Nora, Simões, Bruno M., Clarke, Robert B., Evans, D. Gareth, Ghezelayagh, Talayeh S., Ponandai-Srinivasan, Sakthivignesh, Boggavarapu, Nageswara R., Lalitkumar, Parameswaran G., Howell, Sacha J., Risques, Rosa Ana, Rådestad, Angelique Flöter, Dubeau, Louis, Gemzell-Danielsson, Kristina, Widschwendter, Martin
Publicado 2022