Chemotherapy engages multiple pathways leading to IL-1β production by myeloid leukocytes

por Antonopoulos, Christina, Dubyak, George R
Publicado 2014

Purinergic Receptors: Key Mediators of HIV-1 Infection and Inflammation

por Swartz, Talia H., Dubyak, George R., Chen, Benjamin K.
Publicado 2015

Neutrophil P2X(7) receptors mediate NLRP3 inflammasome-dependent IL-1β secretion in response to ATP

por Karmakar, Mausita, Katsnelson, Michael A., Dubyak, George R., Pearlman, Eric
Publicado 2016

Protein engineering reveals that gasdermin A preferentially targets mitochondrial membranes over the plasma membrane during pyroptosis

por Kondolf, Hannah C., D'Orlando, Dana A., Dubyak, George R., Abbott, Derek W.
Publicado 2023

Ligation of CD40 in Human Müller Cells Induces P2X(7) Receptor–Dependent Death of Retinal Endothelial Cells

por Portillo, Jose-Andres C., Lopez Corcino, Yalitza, Dubyak, George R., Kern, Timothy S., Matsuyama, Shigemi, Subauste, Carlos S.
Publicado 2016

The progressive ankylosis gene product ANK regulates extracellular ATP levels in primary articular chondrocytes

por Rosenthal, Ann K, Gohr, Claudia M, Mitton-Fitzgerald, Elizabeth, Lutz, Megan K, Dubyak, George R, Ryan, Lawrence M
Publicado 2013

Modification of β-Defensin-2 by Dicarbonyls Methylglyoxal and Glyoxal Inhibits Antibacterial and Chemotactic Function In Vitro

por Kiselar, Janna G., Wang, Xiaowei, Dubyak, George R., El Sanadi, Caroline, Ghosh, Santosh K., Lundberg, Kathleen, Williams, Wesley M.
Publicado 2015

CD40 in Retinal Müller Cells Induces P2X(7)-Dependent Cytokine Expression in Macrophages/Microglia in Diabetic Mice and Development of Early Experimental Diabetic Retinopathy

por Portillo, Jose-Andres C., Lopez Corcino, Yalitza, Miao, Yanling, Tang, Jie, Sheibani, Nader, Kern, Timothy S., Dubyak, George R., Subauste, Carlos S.
Publicado 2017

NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity

por Minns, Martin S., Liboro, Karl, Lima, Tatiane S., Abbondante, Serena, Miller, Brandon A., Marshall, Michaela E., Tran Chau, Jolynn, Roistacher, Alicia, Rietsch, Arne, Dubyak, George R., Pearlman, Eric
Publicado 2023

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

por Karmakar, Mausita, Minns, Martin, Greenberg, Elyse N., Diaz-Aponte, Jose, Pestonjamasp, Kersi, Johnson, Jennifer L., Rathkey, Joseph K., Abbott, Derek W., Wang, Kun, Shao, Feng, Catz, Sergio D., Dubyak, George R., Pearlman, Eric
Publicado 2020