Eukaryotic mRNA Decapping Activation

por Vidya, Elva, Duchaine, Thomas F.
Publicado 2022

rna interference and micro rna –oriented therapy in cancer: rationales, promises, and challenges

por Duchaine, T.F., Slack, F.J.
Publicado 2009

On the availability of microRNA-induced silencing complexes, saturation of microRNA-binding sites and stoichiometry

por Mayya, Vinay K., Duchaine, Thomas F.
Publicado 2015

Ciphers and Executioners: How 3′-Untranslated Regions Determine the Fate of Messenger RNAs

por Mayya, Vinay K., Duchaine, Thomas F.
Publicado 2019

Human DDX6 effects miRNA-mediated gene silencing via direct binding to CNOT1

por Rouya, Christopher, Siddiqui, Nadeem, Morita, Masahiro, Duchaine, Thomas F., Fabian, Marc R., Sonenberg, Nahum
Publicado 2014

A non-canonical site reveals the cooperative mechanisms of microRNA-mediated silencing

por Flamand, Mathieu N., Gan, Hin Hark, Mayya, Vinay K., Gunsalus, Kristin C., Duchaine, Thomas F.
Publicado 2017

Distinct, opposing functions for CFIm59 and CFIm68 in mRNA alternative polyadenylation of Pten and in the PI3K/Akt signalling cascade

por Tseng, Hsin-Wei, Mota-Sydor, Anthony, Leventis, Rania, Jovanovic, Predrag, Topisirovic, Ivan, Duchaine, Thomas F
Publicado 2022

Alternative polyadenylation confers Pten mRNAs stability and resistance to microRNAs

por Thivierge, Caroline, Tseng, Hsin-Wei, Mayya, Vinay K, Lussier, Carine, Gravel, Simon-Pierre, Duchaine, Thomas F
Publicado 2018

Poly(A)-binding proteins are required for microRNA-mediated silencing and to promote target deadenylation in C. elegans

por Flamand, Mathieu N., Wu, Edlyn, Vashisht, Ajay, Jannot, Guillaume, Keiper, Brett D., Simard, Martin J., Wohlschlegel, James, Duchaine, Thomas F.
Publicado 2016

microRNA-mediated translation repression through GYF-1 and IFE-4 in C. elegans development

por Mayya, Vinay K, Flamand, Mathieu N, Lambert, Alice M, Jafarnejad, Seyed Mehdi, Wohlschlegel, James A, Sonenberg, Nahum, Duchaine, Thomas F
Publicado 2021

MiR-35 buffers apoptosis thresholds in the C. elegans germline by antagonizing both MAPK and core apoptosis pathways

por Tran, Anh T., Chapman, Eric M., Flamand, Mathieu N., Yu, Bin, Krempel, Samuel J., Duchaine, Thomas F., Eroglu, Matthew, Derry, W. Brent
Publicado 2019

A continuum of mRNP complexes in embryonic microRNA-mediated silencing

por Wu, Edlyn, Vashisht, Ajay A., Chapat, Clément, Flamand, Mathieu N., Cohen, Emiliano, Sarov, Mihail, Tabach, Yuval, Sonenberg, Nahum, Wohlschlegel, James, Duchaine, Thomas F.
Publicado 2017

Naive Human Embryonic Stem Cells Can Give Rise to Cells with a Trophoblast-like Transcriptome and Methylome

por Cinkornpumin, Jessica K., Kwon, Sin Young, Guo, Yixin, Hossain, Ishtiaque, Sirois, Jacinthe, Russett, Colleen S., Tseng, Hsin-Wei, Okae, Hiroaki, Arima, Takahiro, Duchaine, Thomas F., Liu, Wanlu, Pastor, William A.
Publicado 2020

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

por Cipriani, Patricia Giselle, Bay, Olivia, Zinno, John, Gutwein, Michelle, Gan, Hin Hark, Mayya, Vinay K, Chung, George, Chen, Jia-Xuan, Fahs, Hala, Guan, Yu, Duchaine, Thomas F, Selbach, Matthias, Piano, Fabio, Gunsalus, Kristin C
Publicado 2021

Translational control of ERK signaling through miRNA/4EHP-directed silencing

por Jafarnejad, Seyed Mehdi, Chapat, Clément, Matta-Camacho, Edna, Gelbart, Idit Anna, Hesketh, Geoffrey G, Arguello, Meztli, Garzia, Aitor, Kim, Sung-Hoon, Attig, Jan, Shapiro, Maayan, Morita, Masahiro, Khoutorsky, Arkady, Alain, Tommy, Gkogkas, Christos, G, Stern-Ginossar, Noam, Tuschl, Thomas, Gingras, Anne-Claude, Duchaine, Thomas F, Sonenberg, Nahum
Publicado 2018

Repression of LKB1 by miR-17∼92 Sensitizes MYC-Dependent Lymphoma to Biguanide Treatment

por Izreig, Said, Gariepy, Alexandra, Kaymak, Irem, Bridges, Hannah R., Donayo, Ariel O., Bridon, Gaëlle, DeCamp, Lisa M., Kitchen-Goosen, Susan M., Avizonis, Daina, Sheldon, Ryan D., Laister, Rob C., Minden, Mark D., Johnson, Nathalie A., Duchaine, Thomas F., Rudoltz, Marc S., Yoo, Sanghee, Pollak, Michael N., Williams, Kelsey S., Jones, Russell G.
Publicado 2020