White matter neuron biology and neuropathology in schizophrenia

por Duchatel, Ryan J., Shannon Weickert, Cynthia, Tooney, Paul A.
Publicado 2019

Can Hemp Help? Low-THC Cannabis and Non-THC Cannabinoids for the Treatment of Cancer

por Afrin, Farjana, Chi, Mengna, Eamens, Andrew L., Duchatel, Ryan J., Douglas, Alicia M., Schneider, Jennifer, Gedye, Craig, Woldu, Ameha S., Dun, Matthew D.
Publicado 2020

DIPG-32. AKT SIGNALING DRIVES RESISTANCE TO ONC201 IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

por Jackson, Evangeline R, Duchatel, Ryan J, Mannan, Abdul, Hulleman, Esther, Carcaboso, Angel M, Monje, Michelle, McCowage, Geoff B, Alvaro, Frank, Dun, Matthew D
Publicado 2020

Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies

por Findlay, Izac J., De Iuliis, Geoffry N., Duchatel, Ryan J., Jackson, Evangeline R., Vitanza, Nicholas A., Cain, Jason E., Waszak, Sebastian M., Dun, Matthew D.
Publicado 2021

B-cell Lymphoma 6 (BCL6): From Master Regulator of Humoral Immunity to Oncogenic Driver in Pediatric Cancers

por McLachlan, Tabitha, Matthews, William C., Jackson, Evangeline R., Staudt, Dilana E., Douglas, Alicia M., Findlay, Izac J., Persson, Mika L., Duchatel, Ryan J., Mannan, Abdul, Germon, Zacary P., Dun, Matthew D.
Publicado 2022

DIPG-29. PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE 3-KINASE (PI3K) INHIBITION DRIVES PROTEIN KINASE C ACTIVATION (PKC) IN DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG)

por Duchatel, Ryan J, Mannan, Abdul, Jackson, Evangeline R, Staudt, Dilana, Skerrett-Byrne, David A, Jamaluddin, M Fairuz B, Woldu, Ameha S, Douglas, Alicia, Hulleman, Esther, Carcaboso, Angel M, Monje, Michelle, Alvaro, Frank, Tsoli, Maria, Ziegler, David S, Dun, Matthew D
Publicado 2020

Correction to: Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

por Staudt, Dilana E., Murray, Heather C., Skerrett-Byrne, David A., Smith, Nathan D., Jamaluddin, M. Fairuz B., Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary P., McLachlan, Tabitha, Jackson, Evangeline R., Findlay, Izac J., Kearney, Padraic S., Mannan, Abdul, McEwen, Holly P., Douglas, Alicia M., Nixon, Brett, Verrills, Nicole M., Dun, Matthew D.
Publicado 2023

Phospho-heavy-labeled-spiketide FAIMS stepped-CV DDA (pHASED) provides real-time phosphoproteomics data to aid in cancer drug selection

por Staudt, Dilana E., Murray, Heather C., Skerrett-Byrne, David A., Smith, Nathan D., Jamaluddin, M. Fairuz B., Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary P., McLachlan, Tabitha, Jackson, Evangeline R., Findlay, Izac J., Kearney, Padraic S., Mannan, Abdul, McEwen, Holly P., Douglas, Alicia M., Nixon, Brett, Verrills, Nicole M., Dun, Matthew D.
Publicado 2022

Shwachman–Bodian–Diamond syndrome (SBDS) protein is a direct inhibitor of protein phosphatase 2A (PP2A) activity and overexpressed in acute myeloid leukaemia

por Dun, Matthew D., Mannan, Abdul, Rigby, Callum J., Butler, Stephen, Toop, Hamish D., Beck, Dominik, Connerty, Patrick, Sillar, Jonathan, Kahl, Richard G. S., Duchatel, Ryan J., Germon, Zacary, Faulkner, Sam, Chi, Mengna, Skerrett-Byrne, David, Murray, Heather C., Flanagan, Hayley, Almazi, Juhura G., Hondermarck, Hubert, Nixon, Brett, De Iuliis, Geoff, Chamberlain, Janis, Alvaro, Frank, de Bock, Charles E., Morris, Jonathan C., Enjeti, Anoop K., Verrills, Nicole M.
Publicado 2020

Preclinical and clinical evaluation of German-sourced ONC201 for the treatment of H3K27M-mutant diffuse intrinsic pontine glioma

por Duchatel, Ryan J, Mannan, Abdul, Woldu, Ameha S, Hawtrey, Tom, Hindley, Phoebe A, Douglas, Alicia M, Jackson, Evangeline R, Findlay, Izac J, Germon, Zacary P, Staudt, Dilana, Kearney, Padraic S, Smith, Nathan D, Hindley, Kate E, Cain, Jason E, André, Nicolas, La Madrid, Andres Morales, Nixon, Brett, De Iuliis, Geoffry N, Nazarian, Javad, Irish, Kathleen, Alvaro, Frank, Eisenstat, David D, Beck, Alexander, Vitanza, Nicholas A, Mueller, Sabine, Morris, Jonathan C, Dun, Matthew D
Publicado 2021

ONC201 in Combination with Paxalisib for the Treatment of H3K27-Altered Diffuse Midline Glioma

por Jackson, Evangeline R., Duchatel, Ryan J., Staudt, Dilana E., Persson, Mika L., Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W. Samantha N., Grand, Marion Le, Kearney, Padraic S., Douglas, Alicia M., Findlay, Izac J., Germon, Zacary P., McEwen, Holly P., Beitaki, Tyrone S., Patabendige, Adjanie, Skerrett-Byrne, David A., Nixon, Brett, Smith, Nathan D., Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan R., Govender, Dinisha, McCowage, Geoff B., Firestein, Ron, Howlett, Meegan, Endersby, Raelene, Gottardo, Nicholas G., Alvaro, Frank, Waszak, Sebastian M., Larsen, Martin R., Colino-Sanguino, Yolanda, Valdes-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, André, Nicolas, Hulleman, Esther, Eisenstat, David D., Vitanza, Nicholas A., Nazarian, Javad, Koschmann, Carl, Mueller, Sabine, Cain, Jason E., Dun, Matthew D.
Publicado 2023

Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways

por Venneti, Sriram, Kawakibi, Abed Rahman, Ji, Sunjong, Waszak, Sebastian M., Sweha, Stefan R., Mota, Mateus, Pun, Matthew, Deogharkar, Akash, Chung, Chan, Tarapore, Rohinton S., Ramage, Samuel, Chi, Andrew, Wen, Patrick Y., Arrillaga-Romany, Isabel, Batchelor, Tracy T., Butowski, Nicholas A., Sumrall, Ashley, Shonka, Nicole, Harrison, Rebecca A., de Groot, John, Mehta, Minesh, Hall, Matthew D., Daghistani, Doured, Cloughesy, Timothy F., Ellingson, Benjamin M., Beccaria, Kevin, Varlet, Pascale, Kim, Michelle M., Umemura, Yoshie, Garton, Hugh, Franson, Andrea, Schwartz, Jonathan, Jain, Rajan, Kachman, Maureen, Baum, Heidi, Burant, Charles F., Mottl, Sophie L., Cartaxo, Rodrigo T., John, Vishal, Messinger, Dana, Qin, Tingting, Peterson, Erik, Sajjakulnukit, Peter, Ravi, Karthik, Waugh, Alyssa, Walling, Dustin, Ding, Yujie, Xia, Ziyun, Schwendeman, Anna, Hawes, Debra, Yang, Fusheng, Judkins, Alexander R., Wahl, Daniel, Lyssiotis, Costas A., de la Nava, Daniel, Alonso, Marta M., Eze, Augustine, Spitzer, Jasper, Schmidt, Susanne V., Duchatel, Ryan J., Dun, Matthew D., Cain, Jason E., Jiang, Li, Stopka, Sylwia A., Baquer, Gerard, Regan, Michael S., Filbin, Mariella G., Agar, Nathalie Y.R., Zhao, Lili, Kumar-Sinha, Chandan, Mody, Rajen, Chinnaiyan, Arul, Kurokawa, Ryo, Pratt, Drew, Yadav, Viveka N., Grill, Jacques, Kline, Cassie, Mueller, Sabine, Resnick, Adam, Nazarian, Javad, Allen, Joshua E., Odia, Yazmin, Gardner, Sharon L., Koschmann, Carl
Publicado 2023