LRRK2 and Protein Aggregation in Parkinson’s Disease: Insights From Animal Models

por Dues, Dylan J., Moore, Darren J.
Publicado 2020

Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction

por Dues, Dylan J., Nguyen, An Phu Tran, Becker, Katelyn, Ma, Jiyan, Moore, Darren J.
Publicado 2023

Hippocampal subfield vulnerability to α-synuclein pathology precedes neurodegeneration and cognitive dysfunction

por Dues, Dylan J., Nguyen, An Phu Tran, Becker, Katelyn, Ma, Jiyan, Moore, Darren J.
Publicado 2023

Resistance to Stress Can Be Experimentally Dissociated From Longevity

por Dues, Dylan J, Andrews, Emily K, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Publicado 2019

Formation of templated inclusions in a forebrain α-synuclein mouse model is independent of LRRK2

por Dues, Dylan J., Ma, Yue, Nguyen, An Phu Tran, Offerman, Alina V., Beddows, Ian, Moore, Darren J.
Publicado 2023

Delaying aging is neuroprotective in Parkinson’s disease: a genetic analysis in C. elegans models

por Cooper, Jason F, Dues, Dylan J, Spielbauer, Katie K, Machiela, Emily, Senchuk, Megan M, Van Raamsdonk, Jeremy M
Publicado 2015

Activation of the mitochondrial unfolded protein response promotes longevity and dopamine neuron survival in Parkinson’s disease models

por Cooper, Jason F., Machiela, Emily, Dues, Dylan J., Spielbauer, Katie K., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Publicado 2017

Aging causes decreased resistance to multiple stresses and a failure to activate specific stress response pathways

por Dues, Dylan J., Andrews, Emily K., Schaar, Claire E., Bergsma, Alexis L., Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Publicado 2016

Mitochondrial and Cytoplasmic ROS Have Opposing Effects on Lifespan

por Schaar, Claire E., Dues, Dylan J., Spielbauer, Katie K., Machiela, Emily, Cooper, Jason F., Senchuk, Megan, Hekimi, Siegfried, Van Raamsdonk, Jeremy M.
Publicado 2015

Neuronal VPS35 deletion induces spinal cord motor neuron degeneration and early post-natal lethality

por Sargent, Dorian, Cunningham, Lindsey A, Dues, Dylan J, Ma, Yue, Kordich, Jennifer J, Mercado, Gabriela, Brundin, Patrik, Cowell, Rita M, Moore, Darren J
Publicado 2021

Activation of DAF-16/FOXO by reactive oxygen species contributes to longevity in long-lived mitochondrial mutants in Caenorhabditis elegans

por Senchuk, Megan M., Dues, Dylan J., Schaar, Claire E., Johnson, Benjamin K., Madaj, Zachary B., Bowman, Megan J., Winn, Mary E., Van Raamsdonk, Jeremy M.
Publicado 2018

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

por Wu, Ziyun, Senchuk, Megan M., Dues, Dylan J., Johnson, Benjamin K., Cooper, Jason F., Lew, Leira, Machiela, Emily, Schaar, Claire E., DeJonge, Heather, Blackwell, T. Keith, Van Raamsdonk, Jeremy M.
Publicado 2018

Disruption of mitochondrial dynamics increases stress resistance through activation of multiple stress response pathways

por Machiela, Emily, Liontis, Thomas, Dues, Dylan J., Rudich, Paige D., Traa, Annika, Wyman, Leslie, Kaufman, Corah, Cooper, Jason F., Lew, Leira, Nadarajan, Saravanapriah, Senchuk, Megan M., Van Raamsdonk, Jeremy M.
Publicado 2020