Normal Aging Modulates the Neurotoxicity of Mutant Huntingtin

por Diguet, Elsa, Petit, Fanny, Escartin, Carole, Cambon, Karine, Bizat, Nicolas, Dufour, Noëlle, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2009

Dopamine determines the vulnerability of striatal neurons to the N-terminal fragment of mutant huntingtin through the regulation of mitochondrial complex II

por Benchoua, Alexandra, Trioulier, Yaël, Diguet, Elsa, Malgorn, Carole, Gaillard, Marie-Claude, Dufour, Noelle, Elalouf, Jean-Marc, Krajewski, Stan, Hantraye, Philippe, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2008

Allele-Specific RNA Silencing of Mutant Ataxin-3 Mediates Neuroprotection in a Rat Model of Machado-Joseph Disease

por Alves, Sandro, Nascimento-Ferreira, Isabel, Auregan, Gwennaëlle, Hassig, Raymonde, Dufour, Noëlle, Brouillet, Emmanuel, Pedroso de Lima, Maria C., Hantraye, Philippe, Pereira de Almeida, Luís, Déglon, Nicole
Publicado 2008

In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects

por Faideau, Mathilde, Kim, Jinho, Cormier, Kerry, Gilmore, Richard, Welch, Mackenzie, Auregan, Gwennaelle, Dufour, Noelle, Guillermier, Martine, Brouillet, Emmanuel, Hantraye, Philippe, Déglon, Nicole, Ferrante, Robert J., Bonvento, Gilles
Publicado 2010

Neuron-to-neuron wild-type Tau protein transfer through a trans-synaptic mechanism: relevance to sporadic tauopathies

por Dujardin, Simon, Lécolle, Katia, Caillierez, Raphaëlle, Bégard, Séverine, Zommer, Nadège, Lachaud, Cédrick, Carrier, Sébastien, Dufour, Noëlle, Aurégan, Gwennaëlle, Winderickx, Joris, Hantraye, Philippe, Déglon, Nicole, Colin, Morvane, Buée, Luc
Publicado 2014

Preclinical Evaluation of a Lentiviral Vector for Huntingtin Silencing

por Cambon, Karine, Zimmer, Virginie, Martineau, Sylvain, Gaillard, Marie-Claude, Jarrige, Margot, Bugi, Aurore, Miniarikova, Jana, Rey, Maria, Hassig, Raymonde, Dufour, Noelle, Auregan, Gwenaelle, Hantraye, Philippe, Perrier, Anselme L., Déglon, Nicole
Publicado 2017

Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease

por Francelle, Laetitia, Galvan, Laurie, Gaillard, Marie-Claude, Guillermier, Martine, Houitte, Diane, Bonvento, Gilles, Petit, Fanny, Jan, Caroline, Dufour, Noëlle, Hantraye, Philippe, Elalouf, Jean-Marc, De Chaldée, Michel, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2015

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

por Damiano, Maria, Diguet, Elsa, Malgorn, Carole, D'Aurelio, Marilena, Galvan, Laurie, Petit, Fanny, Benhaim, Lucile, Guillermier, Martine, Houitte, Diane, Dufour, Noelle, Hantraye, Philippe, Canals, Josep M., Alberch, Jordi, Delzescaux, Thierry, Déglon, Nicole, Beal, M. Flint, Brouillet, Emmanuel
Publicado 2013

Allele-Specific Silencing of Mutant Huntingtin in Rodent Brain and Human Stem Cells

por Drouet, Valérie, Ruiz, Marta, Zala, Diana, Feyeux, Maxime, Auregan, Gwennaëlle, Cambon, Karine, Troquier, Laetitia, Carpentier, Johann, Aubert, Sophie, Merienne, Nicolas, Bourgois-Rocha, Fany, Hassig, Raymonde, Rey, Maria, Dufour, Noëlle, Saudou, Frédéric, Perrier, Anselme L., Hantraye, Philippe, Déglon, Nicole
Publicado 2014

Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant

por Qamar Saeed, Muhammad, Dufour, Noelle, Bartholmae, Cynthia, Sieranska, Urzula, Knopf, Malaika, Thierry, Eloïse, Thierry, Sylvain, Delelis, Olivier, Grandchamp, Nicolas, Pilet, Héloïse, Ravassard, Philippe, Massonneau, Julie, Pflumio, Françoise, von Kalle, Christof, Lachapelle, François, Bemelmans, Alexis-Pierre, Schmidt, Manfred, Serguera, Ché
Publicado 2014

The C-Terminal Domain of LRRK2 with the G2019S Substitution Increases Mutant A53T α-Synuclein Toxicity in Dopaminergic Neurons In Vivo

por Cresto, Noémie, Gardier, Camille, Gaillard, Marie-Claude, Gubinelli, Francesco, Roost, Pauline, Molina, Daniela, Josephine, Charlène, Dufour, Noëlle, Auregan, Gwenaëlle, Guillermier, Martine, Bernier, Suéva, Jan, Caroline, Gipchtein, Pauline, Hantraye, Philippe, Chartier-Harlin, Marie-Christine, Bonvento, Gilles, Van Camp, Nadja, Taymans, Jean-Marc, Cambon, Karine, Liot, Géraldine, Bemelmans, Alexis-Pierre, Brouillet, Emmanuel
Publicado 2021

The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin

por Galvan, Laurie, Francelle, Laetitia, Gaillard, Marie-Claude, de Longprez, Lucie, Carrillo-de Sauvage, Maria-Angeles, Liot, Géraldine, Cambon, Karine, Stimmer, Lev, Luccantoni, Sophie, Flament, Julien, Valette, Julien, de Chaldée, Michel, Auregan, Gwenaelle, Guillermier, Martine, Joséphine, Charlène, Petit, Fanny, Jan, Caroline, Jarrige, Margot, Dufour, Noëlle, Bonvento, Gilles, Humbert, Sandrine, Saudou, Frédéric, Hantraye, Philippe, Merienne, Karine, Bemelmans, Alexis-Pierre, Perrier, Anselme L, Déglon, Nicole, Brouillet, Emmanuel
Publicado 2018