Bifunctional Peptidomimetic G Protein-Biased Mu-Opioid Receptor Agonist and Neuropeptide FF Receptor Antagonist KGFF09 Shows Efficacy in Visceral Pain without Rewarding Effects aft...

por Dumitrascuta, Maria, Martin, Charlotte, Ballet, Steven, Spetea, Mariana
Publicado 2022

Mechanistic Understanding of Peptide Analogues, DALDA, [Dmt(1)]DALDA, and KGOP01, Binding to the Mu Opioid Receptor

por Dumitrascuta, Maria, Bermudez, Marcel, Ballet, Steven, Wolber, Gerhard, Spetea, Mariana
Publicado 2020

Antinociceptive Efficacy of the µ-Opioid/Nociceptin Peptide-Based Hybrid KGNOP1 in Inflammatory Pain without Rewarding Effects in Mice: An Experimental Assessment and Molecular Doc...

por Dumitrascuta, Maria, Bermudez, Marcel, Trovato, Olga, De Neve, Jolien, Ballet, Steven, Wolber, Gerhard, Spetea, Mariana
Publicado 2021

Synthesis, Pharmacology, and Molecular Docking Studies on 6-Desoxo-N-methylmorphinans as Potent μ-Opioid Receptor Agonists

por Dumitrascuta, Maria, Ben Haddou, Tanila, Guerrieri, Elena, Noha, Stefan M., Schläfer, Lea, Schmidhammer, Helmut, Spetea, Mariana
Publicado 2017

N-Phenethyl Substitution in 14-Methoxy-N-methylmorphinan-6-ones Turns Selective µ Opioid Receptor Ligands into Dual µ/δ Opioid Receptor Agonists

por Dumitrascuta, Maria, Bermudez, Marcel, Ben Haddou, Tanila, Guerrieri, Elena, Schläfer, Lea, Ritsch, Andreas, Hosztafi, Sandor, Lantero, Aquilino, Kreutz, Christoph, Massotte, Dominique, Schmidhammer, Helmut, Wolber, Gerhard, Spetea, Mariana
Publicado 2020

Optimized Opioid-Neurotensin Multitarget Peptides: From Design to Structure–Activity Relationship Studies

por Gonzalez, Simon, Dumitrascuta, Maria, Eiselt, Emilie, Louis, Stevany, Kunze, Linda, Blasiol, Annalisa, Vivancos, Mélanie, Previti, Santo, Dewolf, Elke, Martin, Charlotte, Tourwé, Dirk, Cavelier, Florine, Gendron, Louis, Sarret, Philippe, Spetea, Mariana, Ballet, Steven
Publicado 2020