The Intricate Interplay between Epigenetic Events, Alternative Splicing and Noncoding RNA Deregulation in Colorectal Cancer

por Amirkhah, Raheleh, Naderi-Meshkin, Hojjat, Shah, Jaynish S., Dunne, Philip D., Schmitz, Ulf
Publicado 2019

Comment on “Identification of EMT-related high-risk stage II colorectal cancer and characterisation of metastasis-related genes”

por Loughrey, Maurice B., Fisher, Natalie C., McCooey, Aoife J., Dunne, Philip D.
Publicado 2020

Global colorectal cancer research, 2007‐2021: Outputs and funding

por Begum, Mursheda, Lewison, Grant, Wang, Xiang, Dunne, Philip D., Maughan, Tim, Sullivan, Richard, Lawler, Mark
Publicado 2022

Epithelial‐to‐mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition

por McCorry, Amy MB, Loughrey, Maurice B, Longley, Daniel B, Lawler, Mark, Dunne, Philip D
Publicado 2018

cudaMap: a GPU accelerated program for gene expression connectivity mapping

por McArt, Darragh G, Bankhead, Peter, Dunne, Philip D, Salto-Tellez, Manuel, Hamilton, Peter, Zhang, Shu-Dong
Publicado 2013

Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

por Wen, Qing, O'Reilly, Paul, Dunne, Philip D, Lawler, Mark, Van Schaeybroeck, Sandra, Salto-Tellez, Manuel, Hamilton, Peter, Zhang, Shu-Dong
Publicado 2015

A phase 2 randomised controlled trial of serelaxin to lower portal pressure in cirrhosis (STOPP)

por Gifford, Fiona J., Dunne, Philip D. J., Weir, Graeme, Ireland, Hamish, Graham, Catriona, Tuck, Sharon, Hayes, Peter C., Fallowfield, Jonathan A.
Publicado 2020

Connectivity Mapping for Candidate Therapeutics Identification Using Next Generation Sequencing RNA-Seq Data

por McArt, Darragh G., Dunne, Philip D., Blayney, Jaine K., Salto-Tellez, Manuel, Van Schaeybroeck, Sandra, Hamilton, Peter W., Zhang, Shu-Dong
Publicado 2013

KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies

por Wen, Qing, Dunne, Philip D., O’Reilly, Paul G., Li, Gerald, Bjourson, Anthony J., McArt, Darragh G., Hamilton, Peter W., Zhang, Shu-Dong
Publicado 2016

Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2

por McLaughlin, Declan, Zhao, Youyou, O'Neill, Karla M, Edgar, Kevin S, Dunne, Philip D, Kearney, Anna M, Grieve, David J, McDermott, Barbara J
Publicado 2017

Embracing an integromic approach to tissue biomarker research in cancer: Perspectives and lessons learned

por Li, Gerald, Bankhead, Peter, Dunne, Philip D, O’Reilly, Paul G, James, Jacqueline A, Salto-Tellez, Manuel, Hamilton, Peter W, McArt, Darragh G
Publicado 2017

QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics

por O’Reilly, Paul G., Wen, Qing, Bankhead, Peter, Dunne, Philip D., McArt, Darragh G., McPherson, Suzanne, Hamilton, Peter W., Mills, Ken I., Zhang, Shu-Dong
Publicado 2016

Stratified analysis reveals chemokine-like factor (CKLF) as a potential prognostic marker in the MSI-immune consensus molecular subtype CMS1 of colorectal cancer

por Dunne, Philip D., O'Reilly, Paul G., Coleman, Helen G., Gray, Ronan T., Longley, Daniel B., Johnston, Patrick G., Salto-Tellez, Manuel, Lawler, Mark, McArt, Darragh G.
Publicado 2016

Downregulation of PPARα during Experimental Left Ventricular Hypertrophy is Critically Dependent on Nox2 NADPH Oxidase Signalling

por Harvey, Adam P., Robinson, Emma, Edgar, Kevin S., McMullan, Ross, O’Neill, Karla M., Alderdice, Matthew, Amirkhah, Raheleh, Dunne, Philip D., McDermott, Barbara J., Grieve, David J.
Publicado 2020

Gremlin1 plays a key role in kidney development and renal fibrosis

por Church, Rachel H., Ali, Imran, Tate, Mitchel, Lavin, Deborah, Krishnakumar, Arjun, Kok, Helena M., Hombrebueno, Jose R., Dunne, Philip D., Bingham, Victoria, Goldschmeding, Roel, Martin, Finian, Brazil, Derek P.
Publicado 2017

Fibroblast-derived Gremlin1 localises to epithelial cells at the base of the intestinal crypt

por Dutton, Louise R., Hoare, Owen P., McCorry, Amy M.B., Redmond, Keara L., Adam, Noor Eisa, Canamara, Shannon, Bingham, Victoria, Mullan, Paul B., Lawler, Mark, Dunne, Philip D., Brazil, Derek P.
Publicado 2019

Transcriptional upregulation of c-MET is associated with invasion and tumor budding in colorectal cancer

por Bradley, Conor A., Dunne, Philip D., Bingham, Victoria, McQuaid, Stephen, Khawaja, Hajrah, Craig, Stephanie, James, Jackie, Moore, Wendy L., McArt, Darragh G., Lawler, Mark, Dasgupta, Sonali, Johnston, Patrick G., Van Schaeybroeck, Sandra
Publicado 2016

IHC-based subcellular quantification provides new insights into prognostic relevance of FLIP and procaspase-8 in non-small-cell lung cancer

por Hutchinson, Ryan A, Coleman, Helen G, Gately, Kathy, Young, Vincent, Nicholson, Siobhan, Cummins, Robert, Kay, Elaine, Hynes, Sean O, Dunne, Philip D, Senevirathne, Seedevi, Hamilton, Peter W, McArt, Darragh G, Longley, Daniel B
Publicado 2017

FLINO: a new method for immunofluorescence bioimage normalization

por Graf, John, Cho, Sanghee, McDonough, Elizabeth, Corwin, Alex, Sood, Anup, Lindner, Andreas, Salvucci, Manuela, Stachtea, Xanthi, Van Schaeybroeck, Sandra, Dunne, Philip D, Laurent-Puig, Pierre, Longley, Daniel, Prehn, Jochen H M, Ginty, Fiona
Publicado 2021

QuPath: Open source software for digital pathology image analysis

por Bankhead, Peter, Loughrey, Maurice B., Fernández, José A., Dombrowski, Yvonne, McArt, Darragh G., Dunne, Philip D., McQuaid, Stephen, Gray, Ronan T., Murray, Liam J., Coleman, Helen G., James, Jacqueline A., Salto-Tellez, Manuel, Hamilton, Peter W.
Publicado 2017