PyUUL provides an interface between biological structures and deep learning algorithms

por Orlando, Gabriele, Raimondi, Daniele, Duran-Romaña, Ramon, Moreau, Yves, Schymkowitz, Joost, Rousseau, Frederic
Publicado 2022

SNPeffect 5.0: large-scale structural phenotyping of protein coding variants extracted from next-generation sequencing data using AlphaFold models

por Janssen, Kobe, Duran-Romaña, Ramon, Bottu, Guy, Guharoy, Mainak, Botzki, Alexander, Rousseau, Frederic, Schymkowitz, Joost
Publicado 2023

MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome

por Thues, Cedric, Valadas, Jorge S., Deaulmerie, Liesbeth, Geens, Ann, Chouhan, Amit K., Duran-Romaña, Ramon, Schymkowitz, Joost, Rousseau, Frederic, Bartusel, Michaela, Rehimi, Rizwan, Rada-Iglesias, Alvaro, Verstreken, Patrik, Van Esch, Hilde
Publicado 2021

Exploiting the aggregation propensity of beta-lactamases to design inhibitors that induce enzyme misfolding

por Khodaparast, Ladan, Khodaparast, Laleh, Wu, Guiqin, Michiels, Emiel, Gallardo, Rodrigo, Houben, Bert, Garcia, Teresa, De Vleeschouwer, Matthias, Ramakers, Meine, Wilkinson, Hannah, Duran-Romaña, Ramon, Van Eldere, Johan, Rousseau, Frederic, Schymkowitz, Joost
Publicado 2023

Thermodynamic and Evolutionary Coupling between the Native and Amyloid State of Globular Proteins

por Langenberg, Tobias, Gallardo, Rodrigo, van der Kant, Rob, Louros, Nikolaos, Michiels, Emiel, Duran-Romaña, Ramon, Houben, Bert, Cassio, Rafaela, Wilkinson, Hannah, Garcia, Teresa, Ulens, Chris, Van Durme, Joost, Rousseau, Frederic, Schymkowitz, Joost
Publicado 2020

Identification of genomic enhancers through spatial integration of single‐cell transcriptomics and epigenomics

por Bravo González‐Blas, Carmen, Quan, Xiao‐Jiang, Duran‐Romaña, Ramon, Taskiran, Ibrahim Ihsan, Koldere, Duygu, Davie, Kristofer, Christiaens, Valerie, Makhzami, Samira, Hulselmans, Gert, de Waegeneer, Maxime, Mauduit, David, Poovathingal, Suresh, Aibar, Sara, Aerts, Stein
Publicado 2020

Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein

por Janssen, Kobe, Claes, Filip, Van de Velde, Dido, Wehbi, Vanessa L., Houben, Bert, Lampi, Yulia, Nys, Mieke, Khodaparast, Laleh, Khodaparast, Ladan, Louros, Nikolaos, van der Kant, Rob, Verniers, Joffre, Garcia, Teresa, Ramakers, Meine, Konstantoulea, Katerina, Maragkou, Katerina, Duran-Romaña, Ramon, Musteanu, Mónica, Barbacid, Mariano, Scorneaux, Bernard, Beirnaert, Els, Schymkowitz, Joost, Rousseau, Frederic
Publicado 2023