Spiropyrimidinetriones: a Class of DNA Gyrase Inhibitors with Activity against Mycobacterium tuberculosis and without Cross-Resistance to Fluoroquinolones

por Basarab, Gregory S., Ghorpade, Sandeep, Gibhard, Liezl, Mueller, Rudolf, Njoroge, Mathew, Peton, Nashied, Govender, Preshendren, Massoudi, Lisa M., Robertson, Gregory Thomas, Lenaerts, Anne J., Boshoff, Helena Ingrid, Joerss, Douglas, Parish, Tanya, Durand-Reville, Thomas F., Perros, Manos, Singh, Vinayak, Chibale, Kelly
Publicado 2022

Discovery of an Orally Available Diazabicyclooctane Inhibitor (ETX0282) of Class A, C, and D Serine β-Lactamases

por Durand-Réville, Thomas F., Comita-Prevoir, Janelle, Zhang, Jing, Wu, Xiaoyun, May-Dracka, Tricia L., Romero, Jan Antoinette C., Wu, Frank, Chen, April, Shapiro, Adam B., Carter, Nicole M., McLeod, Sarah M., Giacobbe, Robert A., Verheijen, Jeroen C., Lahiri, Sushmita D., Sacco, Michael D., Chen, Yu, O’Donnell, John P., Miller, Alita A., Mueller, John P., Tommasi, Rubén A.
Publicado 2020