AAV-Mediated Overexpression of Neuroserpin in the Hippocampus Decreases PSD-95 Expression but Does Not Affect Hippocampal-Dependent Learning and Memory

por Tsang, Vicky W. K., Young, Deborah, During, Matthew J., Birch, Nigel P.
Publicado 2014

A Therapeutic Role for Survivin in Mitigating the Harmful Effects of Ionizing Radiation

por Carruthers, Katherine H., Metzger, Gregory, Choi, Eugene, During, Matthew J., Kocak, Ergun
Publicado 2016

Adipose tissue insulin receptor knockdown via a new primate-derived hybrid recombinant AAV serotype

por Liu, Xianglan, Magee, Daniel, Wang, Chuansong, McMurphy, Travis, Slater, Andrew, During, Matthew, Cao, Lei
Publicado 2014

Metabolic Effects of Social Isolation in Adult C57BL/6 Mice

por Sun, Meng, Choi, Eugene Y., Magee, Daniel J., Stets, Colin W., During, Matthew J., Lin, En-Ju D.
Publicado 2014

Gaboxadol Normalizes Behavioral Abnormalities in a Mouse Model of Fragile X Syndrome

por Cogram, Patricia, Deacon, Robert M. J., Warner-Schmidt, Jennifer L., von Schimmelmann, Melanie J., Abrahams, Brett S., During, Matthew J.
Publicado 2019

Adenosine kinase, glutamine synthetase and EAAT2 as gene therapy targets for temporal lobe epilepsy

por Young, Deborah, Fong, Dahna M., Lawlor, Patricia A., Wu, Angela, Mouravlev, Alexandre, McRae, Michelle, Glass, Michelle, Dragunow, Michael, During, Matthew J.
Publicado 2014

An Immunological Approach to Increase the Brain's Resilience to Insults

por Lin, En-Ju D., Symes, C. Wymond, Townsend-Nicholson, Andrea, Klugmann, Matthias, Klugmann, Claudia B., Lehnert, Klaus, Fong, Dahna, Young, Deborah, During, Matthew J.
Publicado 2014

N‐methyl‐d‐aspartate receptor mediated calcium influx supports in vitro differentiation of normal mouse megakaryocytes but proliferation of leukemic cell lines

por Kamal, Tania, Green, Taryn N., Hearn, James I., Josefsson, Emma C., Morel‐Kopp, Marie‐Christine, Ward, Christopher M., During, Matthew J., Kalev‐Zylinska, Maggie L.
Publicado 2017

Novel rat Alzheimer's disease models based on AAV-mediated gene transfer to selectively increase hippocampal Aβ levels

por Lawlor, Patricia A, Bland, Ross J, Das, Pritam, Price, Robert W, Holloway, Vallie, Smithson, Lisa, Dicker, Bridget L, During, Matthew J, Young, Deborah, Golde, Todd E
Publicado 2007

Critical Role of Arcuate Y4 Receptors and the Melanocortin System in Pancreatic Polypeptide-Induced Reduction in Food Intake in Mice

por Lin, Shu, Shi, Yan-Chuan, Yulyaningsih, Ernie, Aljanova, Aygul, Zhang, Lei, Macia, Laurence, Nguyen, Amy D., Lin, En-Ju Deborah, During, Matthew J., Herzog, Herbert, Sainsbury, Amanda
Publicado 2009

Assessment of Tropism and Effectiveness of New Primate-Derived Hybrid Recombinant AAV Serotypes in the Mouse and Primate Retina

por Charbel Issa, Peter, De Silva, Samantha R., Lipinski, Daniel M., Singh, Mandeep S., Mouravlev, Alexandre, You, Qisheng, Barnard, Alun R., Hankins, Mark W., During, Matthew J., MacLaren, Robert E.
Publicado 2013

Soticlestat, a novel cholesterol 24‐hydroxylase inhibitor, reduces seizures and premature death in Dravet syndrome mice

por Hawkins, Nicole A., Jurado, Manuel, Thaxton, Tyler T., Duarte, Samantha E., Barse, Levi, Tatsukawa, Tetsuya, Yamakawa, Kazuhiro, Nishi, Toshiya, Kondo, Shinichi, Miyamoto, Maki, Abrahams, Brett S., During, Matthew J., Kearney, Jennifer A.
Publicado 2021

The STARS Phase 2 Study: A Randomized Controlled Trial of Gaboxadol in Angelman Syndrome

por Bird, Lynne M., Ochoa-Lubinoff, Cesar, Tan, Wen-Hann, Heimer, Gali, Melmed, Raun D., Rakhit, Amit, Visootsak, Jeannie, During, Matthew J., Holcroft, Christina, Burdine, Rebecca D., Kolevzon, Alexander, Thibert, Ronald L.
Publicado 2021

Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics

por Weston, Mikail, Kaserer, Teresa, Wu, Angela, Mouravlev, Alexandre, Carpenter, Jenna C., Snowball, Albert, Knauss, Samuel, von Schimmelmann, Melanie, During, Matthew J., Lignani, Gabriele, Schorge, Stephanie, Young, Deborah, Kullmann, Dimitri M., Lieb, Andreas
Publicado 2019

Platelet-Reactive Antibodies in Patients after Ischaemic Stroke—An Epiphenomenon or a Natural Protective Mechanism

por Park, Young Eun, Penumarthy, Rushi, Sun, Paul P., Kang, Caroline Y., Morel-Kopp, Marie-Christine, Downing, Jonathan, Green, Taryn N., Immanuel, Tracey, Ward, Christopher M., Young, Deborah, During, Matthew J., Barber, P. Alan, Kalev-Zylinska, Maggie L.
Publicado 2020

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice

por Nishi, Toshiya, Kondo, Shinichi, Miyamoto, Maki, Watanabe, Sayuri, Hasegawa, Shigeo, Kondo, Shigeru, Yano, Jason, Watanabe, Etsurou, Ishi, Tsuyoshi, Yoshikawa, Masato, Ando, Haruhi Kamisaki, Farnaby, William, Fujimoto, Shinji, Sunahara, Eiji, Ohori, Momoko, During, Matthew J., Kuroita, Takanobu, Koike, Tatsuki
Publicado 2020

Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial

por MacLaren, Robert E, Groppe, Markus, Barnard, Alun R, Cottriall, Charles L, Tolmachova, Tanya, Seymour, Len, Clark, K Reed, During, Matthew J, Cremers, Frans P M, Black, Graeme C M, Lotery, Andrew J, Downes, Susan M, Webster, Andrew R, Seabra, Miguel C
Publicado 2014

Evidence That GRIN2A Mutations in Melanoma Correlate with Decreased Survival

por D’mello, Stacey Ann N., Flanagan, Jack U., Green, Taryn N., Leung, Euphemia Y., Askarian-Amiri, Marjan E., Joseph, Wayne R., McCrystal, Michael R., Isaacs, Richard J., Shaw, James H. F., Furneaux, Christopher E., During, Matthew J., Finlay, Graeme J., Baguley, Bruce C., Kalev-Zylinska, Maggie L.
Publicado 2014

Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight

por Baldock, Paul A., Lee, Nicola J., Driessler, Frank, Lin, Shu, Allison, Susan, Stehrer, Bernhard, Lin, En-Ju D., Zhang, Lei, Enriquez, Ronald F., Wong, Iris P. L., McDonald, Michelle M., During, Matthew, Pierroz, Dominique D., Slack, Katy, Shi, Yan C., Yulyaningsih, Ernie, Aljanova, Aygul, Little, David G., Ferrari, Serge L., Sainsbury, Amanda, Eisman, John A., Herzog, Herbert
Publicado 2009