PI3K inhibitors in thrombosis and cardiovascular disease

por Durrant, Tom N., Hers, Ingeborg
Publicado 2020

Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function

por Moore, Samantha F., Smith, Nina R., Blair, Thomas A., Durrant, Tom N., Hers, Ingeborg
Publicado 2019

Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP(2) in the Mouse

por Anderson, Karen E., Kielkowska, Anna, Durrant, Tom N., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.
Publicado 2013

Quantitation of class IA PI3Ks in mice reveals p110-free-p85s and isoform-selective subunit associations and recruitment to receptors

por Tsolakos, N., Durrant, T. N., Chessa, T., Suire, S. M., Oxley, D., Kulkarni, S., Downward, J., Perisic, O., Williams, R. L., Stephens, L., Hawkins, P. T.
Publicado 2018

The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin α(IIb)β(3) Outside-in Signaling

por Battram, Anthony M., Durrant, Tom N., Agbani, Ejaife O., Heesom, Kate J., Paul, David S., Piatt, Raymond, Poole, Alastair W., Cullen, Peter J., Bergmeier, Wolfgang, Moore, Samantha F., Hers, Ingeborg
Publicado 2017

Hepatocyte mARC1 promotes fatty liver disease

por Lewis, Lara C., Chen, Lingyan, Hameed, L. Shahul, Kitchen, Robert R., Maroteau, Cyrielle, Nagarajan, Shilpa R., Norlin, Jenny, Daly, Charlotte E., Szczerbinska, Iwona, Hjuler, Sara Toftegaard, Patel, Rahul, Livingstone, Eilidh J., Durrant, Tom N., Wondimu, Elisabeth, BasuRay, Soumik, Chandran, Anandhakumar, Lee, Wan-Hung, Hu, Sile, Gilboa, Barak, Grandi, Megan E., Toledo, Enrique M., Erikat, Abdullah H.A., Hodson, Leanne, Haynes, William G., Pursell, Natalie W., Coppieters, Ken, Fleckner, Jan, Howson, Joanna M.M., Andersen, Birgitte, Ruby, Maxwell A.
Publicado 2023