Real-time single cell analysis of Smac/DIABLO release during apoptosis

por Rehm, Markus, Düßmann, Heiko, Prehn, Jochen H.M.
Publicado 2003

Metabolic Targeting of Breast Cancer Cells With the 2-Deoxy-D-Glucose and the Mitochondrial Bioenergetics Inhibitor MDIVI-1

por Lucantoni, Federico, Dussmann, Heiko, Prehn, Jochen H. M.
Publicado 2018

BCL2 and BCL(X)L selective inhibitors decrease mitochondrial ATP production in breast cancer cells and are synthetically lethal when combined with 2-deoxy-D-glucose

por Lucantoni, Federico, Düssmann, Heiko, Llorente-Folch, Irene, Prehn, Jochen H.M.
Publicado 2018

Mitochondrial Carrier Homolog 2 Functionally Co-operates With BH3 Interacting-Domain Death Agonist in Promoting Ca(2+)-Induced Neuronal Injury

por D’Orsi, Beatrice, Niewidok, Natalia, Düssmann, Heiko, Prehn, Jochen H. M.
Publicado 2021

Single-cell time-lapse imaging of intracellular O(2) in response to metabolic inhibition and mitochondrial cytochrome-c release

por Düssmann, Heiko, Perez-Alvarez, Sergio, Anilkumar, Ujval, Papkovsky, Dmitri B, Prehn, Jochen HM
Publicado 2017

BOK controls ER proteostasis and physiological ER stress responses in neurons

por Walter, Franziska, D’Orsi, Beatrice, Jagannathan, Anagha, Dussmann, Heiko, Prehn, Jochen H. M.
Publicado 2022

Glucose metabolism determines resistance of cancer cells to bioenergetic crisis after cytochrome-c release

por Huber, Heinrich J, Dussmann, Heiko, Kilbride, Seán M, Rehm, Markus, Prehn, Jochen H M
Publicado 2011

Systems modeling accurately predicts responses to genotoxic agents and their synergism with BCL-2 inhibitors in triple negative breast cancer cells

por Lucantoni, Federico, Lindner, Andreas U., O’Donovan, Norma, Düssmann, Heiko, Prehn, Jochen H. M.
Publicado 2018

Transcriptional CDK Inhibitors CYC065 and THZ1 Induce Apoptosis in Glioma Stem Cells Derived from Recurrent GBM

por Juric, Viktorija, Düssmann, Heiko, Lamfers, Martine L. M., Prehn, Jochen H. M., Rehm, Markus, Murphy, Brona M.
Publicado 2021

Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study

por Kealey, James, Düssmann, Heiko, Llorente-Folch, Irene, Niewidok, Natalia, Salvucci, Manuela, Prehn, Jochen H. M., D’Orsi, Beatrice
Publicado 2022

Defining external factors that determine neuronal survival, apoptosis and necrosis during excitotoxic injury using a high content screening imaging platform

por Anilkumar, Ujval, Weisova, Petronela, Schmid, Jasmin, Bernas, Tytus, Huber, Heinrich J., Düssmann, Heiko, Connolly, Niamh M. C., Prehn, Jochen H. M.
Publicado 2017

TRAIL signaling promotes entosis in colorectal cancer

por Bozkurt, Emir, Düssmann, Heiko, Salvucci, Manuela, Cavanagh, Brenton L., Van Schaeybroeck, Sandra, Longley, Daniel B., Martin, Seamus J., Prehn, Jochen H.M.
Publicado 2021

The Anti-inflammatory Compound Candesartan Cilexetil Improves Neurological Outcomes in a Mouse Model of Neonatal Hypoxia

por Quinlan, Sean, Merino-Serrais, Paula, Di Grande, Alessandra, Dussmann, Heiko, Prehn, Jochen H. M., Ní Chonghaile, Tríona, Henshall, David C., Jimenez-Mateos, Eva M.
Publicado 2019

Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant

por Fichtner, Michael, Bozkurt, Emir, Salvucci, Manuela, McCann, Christopher, McAllister, Katherine A., Halang, Luise, Düssmann, Heiko, Kinsella, Sinéad, Crawford, Nyree, Sessler, Tamas, Longley, Daniel B., Prehn, Jochen H. M.
Publicado 2020

Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome

por Duggan, William P., Salvucci, Manuela, Kisakol, Batuhan, Lindner, Andreas U., Reynolds, Ian S., Dussmann, Heiko, Fay, Joanna, O’Grady, Tony, Longley, Daniel B., Ginty, Fiona, Mc Donough, Elizabeth, Slade, Daniel J., Burke, John P., Prehn, Jochen H. M.
Publicado 2023

INS-1 Cells Undergoing Caspase-Dependent Apoptosis Enhance the Regenerative Capacity of Neighboring Cells

por Bonner, Caroline, Bacon, Siobhán, Concannon, Caoimhín G., Rizvi, Syed R., Baquié, Mathurin, Farrelly, Angela M., Kilbride, Seán M., Dussmann, Heiko, Ward, Manus W., Boulanger, Chantal M., Wollheim, Claes B., Graf, Rolf, Byrne, Maria M., Prehn, Jochen H.M.
Publicado 2010

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer

por Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní
Publicado 2021

Comparative analysis of deeply phenotyped GBM cohorts of ‘short-term’ and ‘long-term’ survivors

por Biswas, Archita, Salvucci, Manuela, Connor, Kate, Düssmann, Heiko, Carberry, Steven, Fichtner, Michael, King, Ellen, Murphy, Brona, O’Farrell, Alice C., Cryan, Jane, Beausang, Alan, Heffernan, Josephine, Cremona, Mattia, Hennessy, Bryan T., Clerkin, James, Sweeney, Kieron J., MacNally, Steve, Brett, Francesca, O’Halloran, Philip, Bacon, Orna, Furney, Simon, Verreault, Maite, Quissac, Emie, Bielle, Franck, Ahmed, Mohammed H., Idbaih, Ahmed, Leenstra, Sieger, Ntafoulis, Ioannis, Fabro, Federica, Lamfers, Martine, Golebiewska, Anna, Hertel, Frank, Niclou, Simone P., Yen, Romain Tching Chi, Kremer, Andreas, Dilcan, Gonca, Lodi, Francesca, Arijs, Ingrid, Lambrechts, Diether, Purushothama, Manasa Kalya, Kel, Alexander, Byrne, Annette T., Prehn, Jochen H.M.
Publicado 2023

Guidelines on experimental methods to assess mitochondrial dysfunction in cellular models of neurodegenerative diseases

por Connolly, Niamh M. C., Theurey, Pierre, Adam-Vizi, Vera, Bazan, Nicolas G., Bernardi, Paolo, Bolaños, Juan P., Culmsee, Carsten, Dawson, Valina L., Deshmukh, Mohanish, Duchen, Michael R., Düssmann, Heiko, Fiskum, Gary, Galindo, Maria F., Hardingham, Giles E., Hardwick, J. Marie, Jekabsons, Mika B., Jonas, Elizabeth A., Jordán, Joaquin, Lipton, Stuart A., Manfredi, Giovanni, Mattson, Mark P., McLaughlin, BethAnn, Methner, Axel, Murphy, Anne N., Murphy, Michael P., Nicholls, David G., Polster, Brian M., Pozzan, Tullio, Rizzuto, Rosario, Satrústegui, Jorgina, Slack, Ruth S., Swanson, Raymond A., Swerdlow, Russell H., Will, Yvonne, Ying, Zheng, Joselin, Alvin, Gioran, Anna, Moreira Pinho, Catarina, Watters, Orla, Salvucci, Manuela, Llorente-Folch, Irene, Park, David S., Bano, Daniele, Ankarcrona, Maria, Pizzo, Paola, Prehn, Jochen H. M.
Publicado 2017