Effect of Toxicants on Fatty Acid Metabolism in HepG2 Cells

por Grünig, David, Duthaler, Urs, Krähenbühl, Stephan
Publicado 2018

Repurposing drugs for the treatment and control of helminth infections

por Panic, Gordana, Duthaler, Urs, Speich, Benjamin, Keiser, Jennifer
Publicado 2014

Cytochrome P450 Enzymes Involved in Metoprolol Metabolism and Use of Metoprolol as a CYP2D6 Phenotyping Probe Drug

por Berger, Benjamin, Bachmann, Fabio, Duthaler, Urs, Krähenbühl, Stephan, Haschke, Manuel
Publicado 2018

Cytochrome P450 1A2 is the most important enzyme for hepatic metabolism of the metamizole metabolite 4‐methylaminoantipyrine

por Bachmann, Fabio, Meyer zu Schwabedissen, Henriette E., Duthaler, Urs, Krähenbühl, Stephan
Publicado 2021

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

por Kern, Charlotte, Müller, Pie, Chaccour, Carlos, Liechti, Matthias E., Hammann, Felix, Duthaler, Urs
Publicado 2023

Impaired Exercise Performance and Skeletal Muscle Mitochondrial Function in Rats with Secondary Carnitine Deficiency

por Bouitbir, Jamal, Haegler, Patrizia, Singh, François, Joerin, Lorenz, Felser, Andrea, Duthaler, Urs, Krähenbühl, Stephan
Publicado 2016

The Activity of Members of the UDP-Glucuronosyltransferase Subfamilies UGT1A and UGT2B is Impaired in Patients with Liver Cirrhosis

por Duthaler, Urs, Bachmann, Fabio, Ozbey, Agustos C., Umehara, Kenichi, Parrott, Neil, Fowler, Stephen, Krähenbühl, Stephan
Publicado 2023

Single-Ascending-Dose Pharmacokinetic Study of Tribendimidine in Opisthorchis viverrini-Infected Patients

por Duthaler, Urs, Sayasone, Somphou, Vanobbergen, Fiona, Penny, Melissa A., Odermatt, Peter, Huwyler, Jörg, Keiser, Jennifer
Publicado 2016

Population Pharmacokinetic Modeling of Tribendimidine Metabolites in Opisthorchis viverrini-Infected Adults

por Vanobberghen, Fiona, Penny, Melissa A., Duthaler, Urs, Odermatt, Peter, Sayasone, Somphou, Keiser, Jennifer, Tarning, Joel
Publicado 2016

Pharmacokinetic Study of Praziquantel Enantiomers and Its Main Metabolite R-trans-4-OH-PZQ in Plasma, Blood and Dried Blood Spots in Opisthorchis viverrini-Infected Patients

por Meister, Isabel, Kovac, Jana, Duthaler, Urs, Odermatt, Peter, Huwyler, Jörg, Vanobberghen, Fiona, Sayasone, Somphou, Keiser, Jennifer
Publicado 2016

The pharmacokinetics and drug-drug interactions of ivermectin in Aedes aegypti mosquitoes

por Duthaler, Urs, Weber, Michael, Hofer, Lorenz, Chaccour, Carlos, Maia, Marta, Müller, Pie, Krähenbühl, Stephan, Hammann, Felix
Publicado 2021

Particle Forming Amorphous Solid Dispersions: A Mechanistic Randomized Pharmacokinetic Study in Humans

por Schittny, Andreas, Waldner, Samuel, Duthaler, Urs, Vorobyev, Alexander, Abramovich, Rimma, Krähenbühl, Stephan, Puchkov, Maxim, Huwyler, Jörg
Publicado 2021

Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study

por Nicolas, Patricia, Kiuru, Caroline, Wagah, Martin G., Muturi, Martha, Duthaler, Urs, Hammann, Felix, Maia, Marta, Chaccour, Carlos
Publicado 2021

Metamizole is a Moderate Cytochrome P450 Inducer Via the Constitutive Androstane Receptor and a Weak Inhibitor of CYP1A2

por Bachmann, Fabio, Duthaler, Urs, Meyer zu Schwabedissen, Henriette E., Puchkov, Maxim, Huwyler, Jörg, Haschke, Manuel, Krähenbühl, Stephan
Publicado 2021

Liver Cirrhosis Affects the Pharmacokinetics of the Six Substrates of the Basel Phenotyping Cocktail Differently

por Duthaler, Urs, Bachmann, Fabio, Suenderhauf, Claudia, Grandinetti, Tanja, Pfefferkorn, Florian, Haschke, Manuel, Hruz, Petr, Bouitbir, Jamal, Krähenbühl, Stephan
Publicado 2022

Effects of 3,4-Methylenedioxymethamphetamine on Conditioned Fear Extinction and Retention in a Crossover Study in Healthy Subjects

por Vizeli, Patrick, Straumann, Isabelle, Duthaler, Urs, Varghese, Nimmy, Eckert, Anne, Paulus, Martin P., Risbrough, Victoria, Liechti, Matthias E.
Publicado 2022

Ketanserin Reverses the Acute Response to LSD in a Randomized, Double-Blind, Placebo-Controlled, Crossover Study in Healthy Participants

por Becker, Anna M, Klaiber, Aaron, Holze, Friederike, Istampoulouoglou, Ioanna, Duthaler, Urs, Varghese, Nimmy, Eckert, Anne, Liechti, Matthias E
Publicado 2022

Improvement of muscle strength in a mouse model for congenital myopathy treated with HDAC and DNA methyltransferase inhibitors

por Ruiz, Alexis, Benucci, Sofia, Duthaler, Urs, Bachmann, Christoph, Franchini, Martina, Noreen, Faiza, Pietrangelo, Laura, Protasi, Feliciano, Treves, Susan, Zorzato, Francesco
Publicado 2022

Acute effects of MDMA and LSD co-administration in a double-blind placebo-controlled study in healthy participants

por Straumann, Isabelle, Ley, Laura, Holze, Friederike, Becker, Anna M., Klaiber, Aaron, Wey, Kathrin, Duthaler, Urs, Varghese, Nimmy, Eckert, Anne, Liechti, Matthias E.
Publicado 2023

Comparative Effects of Metamizole (Dipyrone) and Naproxen on Renal Function and Prostacyclin Synthesis in Salt-Depleted Healthy Subjects - A Randomized Controlled Parallel Group St...

por Blaser, Lea S, Duthaler, Urs, Bouitbir, Jamal, Leuppi-Taegtmeyer, Anne B, Liakoni, Evangelia, Dolf, Reto, Mayr, Michael, Drewe, Jürgen, Krähenbühl, Stephan, Haschke, Manuel
Publicado 2021