Bidirectional Modulation of the Voltage-Gated Sodium (Nav1.6) Channel by Rationally Designed Peptidomimetics

por Dvorak, Nolan M., Wadsworth, Paul A., Wang, Pingyuan, Chen, Haiying, Zhou, Jia, Laezza, Fernanda
Publicado 2020

Voltage-Gated Na(+) Channels in Alzheimer’s Disease: Physiological Roles and Therapeutic Potential

por Baumgartner, Timothy J., Haghighijoo, Zahra, Goode, Nana A., Dvorak, Nolan M., Arman, Parsa, Laezza, Fernanda
Publicado 2023

Inhibition of the Akt/PKB Kinase Increases Na(v)1.6-Mediated Currents and Neuronal Excitability in CA1 Hippocampal Pyramidal Neurons

por Marosi, Mate, Nenov, Miroslav N., Di Re, Jessica, Dvorak, Nolan M., Alshammari, Musaad, Laezza, Fernanda
Publicado 2022

Pharmacological Inhibition of Wee1 Kinase Selectively Modulates the Voltage-Gated Na(+) Channel 1.2 Macromolecular Complex

por Dvorak, Nolan M., Tapia, Cynthia M., Baumgartner, Timothy J., Singh, Jully, Laezza, Fernanda, Singh, Aditya K.
Publicado 2021

Differential Modulation of the Voltage-Gated Na(+) Channel 1.6 by Peptides Derived From Fibroblast Growth Factor 14

por Singh, Aditya K., Dvorak, Nolan M., Tapia, Cynthia M., Mosebarger, Angela, Ali, Syed R., Bullock, Zaniqua, Chen, Haiying, Zhou, Jia, Laezza, Fernanda
Publicado 2021

Pharmacologically Targeting the Fibroblast Growth Factor 14 Interaction Site on the Voltage-Gated Na(+) Channel 1.6 Enables Isoform-Selective Modulation

por Dvorak, Nolan M., Tapia, Cynthia M., Singh, Aditya K., Baumgartner, Timothy J., Wang, Pingyuan, Chen, Haiying, Wadsworth, Paul A., Zhou, Jia, Laezza, Fernanda
Publicado 2021