Cancer Microenvironment: What Can We Learn from the Stem Cell Niche

por Lacina, Lukas, Plzak, Jan, Kodet, Ondrej, Szabo, Pavol, Chovanec, Martin, Dvorankova, Barbora, Smetana, Karel
Publicado 2015

Cutaneous melanoma dissemination is dependent on the malignant cell properties and factors of intercellular crosstalk in the cancer microenvironment (Review)

por Kodet, Ondřej, Kučera, Jan, Strnadová, Karolína, Dvořánková, Barbora, Štork, Jiří, Lacina, Lukáš, Smetana, Karel
Publicado 2020

IL-6 in the Ecosystem of Head and Neck Cancer: Possible Therapeutic Perspectives

por Španko, Michal, Strnadová, Karolína, Pavlíček, Aleš Jan, Szabo, Pavol, Kodet, Ondřej, Valach, Jaroslav, Dvořánková, Barbora, Smetana, Karel, Lacina, Lukáš
Publicado 2021

Single-Cell RNA Sequencing Unravels Heterogeneity of the Stromal Niche in Cutaneous Melanoma Heterogeneous Spheroids

por Novotný, Jiří, Strnadová, Karolína, Dvořánková, Barbora, Kocourková, Šárka, Jakša, Radek, Dundr, Pavel, Pačes, Václav, Smetana, Karel, Kolář, Michal, Lacina, Lukáš
Publicado 2020

Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19

por Brábek, Jan, Jakubek, Milan, Vellieux, Fréderic, Novotný, Jiří, Kolář, Michal, Lacina, Lukáš, Szabo, Pavol, Strnadová, Karolína, Rösel, Daniel, Dvořánková, Barbora, Smetana, Karel
Publicado 2020

Molecular Changes Underlying Hypertrophic Scarring Following Burns Involve Specific Deregulations at All Wound Healing Stages (Inflammation, Proliferation and Maturation)

por Čoma, Matúš, Fröhlichová, Lucia, Urban, Lukáš, Zajíček, Robert, Urban, Tomáš, Szabo, Pavol, Novák, Štěpán, Fetissov, Vitaly, Dvořánková, Barbora, Smetana, Karel, Gál, Peter
Publicado 2021

Melanoma cells influence the differentiation pattern of human epidermal keratinocytes

por Kodet, Ondřej, Lacina, Lukáš, Krejčí, Eliška, Dvořánková, Barbora, Grim, Miloš, Štork, Jiří, Kodetová, Daniela, Vlček, Čestmír, Šáchová, Jana, Kolář, Michal, Strnad, Hynek, Smetana, Karel
Publicado 2015

Estrogen Receptor Modulators in Viral Infections Such as SARS−CoV−2: Therapeutic Consequences

por Abramenko, Nikita, Vellieux, Fréderic, Tesařová, Petra, Kejík, Zdeněk, Kaplánek, Robert, Lacina, Lukáš, Dvořánková, Barbora, Rösel, Daniel, Brábek, Jan, Tesař, Adam, Jakubek, Milan, Smetana, Karel
Publicado 2021

Functional differences between neonatal and adult fibroblasts and keratinocytes: Donor age affects epithelial-mesenchymal crosstalk in vitro

por Mateu, Rosana, Živicová, Veronika, Krejčí, Eliška Drobná, Grim, Miloš, Strnad, Hynek, Vlček, Čestmír, Kolář, Michal, Lacina, Lukáš, Gál, Peter, Borský, Jiří, Smetana, Karel, Dvořánková, Barbora
Publicado 2016

Microenvironment-driven resistance to B-Raf inhibition in a melanoma patient is accompanied by broad changes of gene methylation and expression in distal fibroblasts

por Kodet, Ondřej, Dvořánková, Barbora, Bendlová, Běla, Sýkorová, Vlasta, Krajsová, Ivana, Štork, Jiří, Kučera, Jan, Szabo, Pavol, Strnad, Hynek, Kolář, Michal, Vlček, Čestmír, Smetana, Karel, Lacina, Lukáš
Publicado 2018

Serum proteomic analysis of melanoma patients with immunohistochemical profiling of primary melanomas and cultured cells: Pilot study

por Kučera, Jan, Strnadová, Karolína, Dvořánková, Barbora, Lacina, Lukáš, Krajsová, Ivana, Štork, Jiří, Kovářová, Hana, Skalníková, Helena Kupcová, Vodička, Petr, Motlík, Jan, Dundr, Pavel, Smetana, Karel, Kodet, Ondřej
Publicado 2019

Unravelling heterogeneous effects of cancer‑associated fibroblasts on poor prognosis markers in breast cancer EM‑G3 cell line: In vitro‑targeted treatment (anti‑IL-6, anti‑VEGF-A,...

por Urban, Lukáš, Novák, Štepán, Čoma, Matúš, Dvořánková, Barbora, Lacina, Lukáš, Šáchová, Jana, Hradilová, Miluše, Svatoňová, Petra, Kolář, Michal, Strnad, Hynek, Březinová, Jana, Smetana, Karel, Gál, Peter, Szabo, Pavol
Publicado 2023

Analysis of dermal fibroblasts isolated from neonatal and child cleft lip and adult skin: Developmental implications on reconstructive surgery

por Živicová, Veronika, Lacina, Lukáš, Mateu, Rosana, Smetana, Karel, Kavková, Radana, Krejčí, Eliška Drobná, Grim, Miloš, Kvasilová, Alena, Borský, Jiří, Strnad, Hynek, Hradilová, Miluše, Šáchová, Jana, Kolář, Michal, Dvořánková, Barbora
Publicado 2017

Exosomes produced by melanoma cells significantly influence the biological properties of normal and cancer-associated fibroblasts

por Strnadová, Karolína, Pfeiferová, Lucie, Přikryl, Petr, Dvořánková, Barbora, Vlčák, Erik, Frýdlová, Jana, Vokurka, Martin, Novotný, Jiří, Šáchová, Jana, Hradilová, Miluše, Brábek, Jan, Šmigová, Jana, Rösel, Daniel, Smetana, Karel, Kolář, Michal, Lacina, Lukáš
Publicado 2021

Novel PD-L1- and collagen-expressing patient-derived cell line of undifferentiated pleomorphic sarcoma (JBT19) as a model for cancer immunotherapy

por Taborska, Pavla, Lukac, Pavol, Stakheev, Dmitry, Rajsiglova, Lenka, Kalkusova, Katerina, Strnadova, Karolina, Lacina, Lukas, Dvorankova, Barbora, Novotny, Jiri, Kolar, Michal, Vrana, Milena, Cechova, Hana, Ransdorfova, Sarka, Valerianova, Marie, Smetana, Karel, Vannucci, Luca, Smrz, Daniel
Publicado 2023

New-Generation Heterocyclic Bis-Pentamethinium Salts as Potential Cytostatic Drugs with Dual IL-6R and Mitochondria-Targeting Activity

por Talianová, Veronika, Kejík, Zdeněk, Kaplánek, Robert, Veselá, Kateřina, Abramenko, Nikita, Lacina, Lukáš, Strnadová, Karolína, Dvořánková, Barbora, Martásek, Pavel, Masařík, Michal, Megová, Magdalena Houdová, Bušek, Petr, Křížová, Jana, Zdražilová, Lucie, Hansíková, Hana, Vlčák, Erik, Filimonenko, Vlada, Šedo, Aleksi, Smetana, Karel, Jakubek, Milan
Publicado 2022