Molecular and Functional Relevance of Na(V)1.8-Induced Atrial Arrhythmogenic Triggers in a Human SCN10A Knock-Out Stem Cell Model

por Hartmann, Nico, Knierim, Maria, Maurer, Wiebke, Dybkova, Nataliya, Hasenfuß, Gerd, Sossalla, Samuel, Streckfuss-Bömeke, Katrin
Publicado 2023

Long-term effects of empagliflozin on excitation-contraction-coupling in human induced pluripotent stem cell cardiomyocytes

por Pabel, Steffen, Reetz, Florian, Dybkova, Nataliya, Shomroni, Orr, Salinas, Gabriela, Mustroph, Julian, Hammer, Karin P., Hasenfuss, Gerd, Hamdani, Nazha, Maier, Lars S., Streckfuss-Bömeke, Katrin, Sossalla, Samuel
Publicado 2020

The functional consequences of sodium channel Na(V)1.8 in human left ventricular hypertrophy

por Ahmad, Shakil, Tirilomis, Petros, Pabel, Steffen, Dybkova, Nataliya, Hartmann, Nico, Molina, Cristina E., Tirilomis, Theodoros, Kutschka, Ingo, Frey, Norbert, Maier, Lars S., Hasenfuss, Gerd, Streckfuss‐Bömeke, Katrin, Sossalla, Samuel
Publicado 2018

Inhibition of Na(V)1.8 prevents atrial arrhythmogenesis in human and mice

por Pabel, Steffen, Ahmad, Shakil, Tirilomis, Petros, Stehle, Thea, Mustroph, Julian, Knierim, Maria, Dybkova, Nataliya, Bengel, Philipp, Holzamer, Andreas, Hilker, Michael, Streckfuss-Bömeke, Katrin, Hasenfuss, Gerd, Maier, Lars S., Sossalla, Samuel
Publicado 2020

Enhanced cardiac TBC1D10C expression lowers heart rate and enhances exercise capacity and survival

por Volland, Cornelia, Bremer, Sebastian, Hellenkamp, Kristian, Hartmann, Nico, Dybkova, Nataliya, Khadjeh, Sara, Kutschenko, Anna, Liebetanz, David, Wagner, Stefan, Unsöld, Bernhard, Didié, Michael, Toischer, Karl, Sossalla, Samuel, Hasenfuß, Gerd, Seidler, Tim
Publicado 2016

Cellular Mechanisms of the Anti-Arrhythmic Effect of Cardiac PDE2 Overexpression

por Wagner, Michael, Sadek, Mirna S., Dybkova, Nataliya, Mason, Fleur E., Klehr, Johann, Firneburg, Rebecca, Cachorro, Eleder, Richter, Kurt, Klapproth, Erik, Kuenzel, Stephan R., Lorenz, Kristina, Heijman, Jordi, Dobrev, Dobromir, El-Armouche, Ali, Sossalla, Samuel, Kämmerer, Susanne
Publicado 2021

Detrimental proarrhythmogenic interaction of Ca(2+)/calmodulin-dependent protein kinase II and Na(V)1.8 in heart failure

por Bengel, Philipp, Dybkova, Nataliya, Tirilomis, Petros, Ahmad, Shakil, Hartmann, Nico, A. Mohamed, Belal, Krekeler, Miriam Celine, Maurer, Wiebke, Pabel, Steffen, Trum, Maximilian, Mustroph, Julian, Gummert, Jan, Milting, Hendrik, Wagner, Stefan, Ljubojevic-Holzer, Senka, Toischer, Karl, Maier, Lars S., Hasenfuss, Gerd, Streckfuss-Bömeke, Katrin, Sossalla, Samuel
Publicado 2021

Effects of Atrial Fibrillation on the Human Ventricle

por Pabel, Steffen, Knierim, Maria, Stehle, Thea, Alebrand, Felix, Paulus, Michael, Sieme, Marcel, Herwig, Melissa, Barsch, Friedrich, Körtl, Thomas, Pöppl, Arnold, Wenner, Brisca, Ljubojevic-Holzer, Senka, Molina, Cristina E., Dybkova, Nataliya, Camboni, Daniele, Fischer, Thomas H., Sedej, Simon, Scherr, Daniel, Schmid, Christof, Brochhausen, Christoph, Hasenfuß, Gerd, Maier, Lars S., Hamdani, Nazha, Streckfuss-Bömeke, Katrin, Sossalla, Samuel
Publicado 2022