Bortezomib Warhead-Switch Confers Dual Activity against Mycobacterial Caseinolytic Protease and Proteasome and Selectivity against Human Proteasome

por Moreira, Wilfried, Santhanakrishnan, Sridhar, Dymock, Brian W., Dick, Thomas
Publicado 2017

Fragment-Based Whole Cell Screen Delivers Hits against M. tuberculosis and Non-tuberculous Mycobacteria

por Moreira, Wilfried, Lim, Jia Jie, Yeo, Si Ying, Ramanujulu, Pondy M., Dymock, Brian W., Dick, Thomas
Publicado 2016

Antioxidants inhibit neuronal toxicity in Parkinson's disease‐linked LRRK2

por Angeles, Dario C., Ho, Patrick, Dymock, Brian W., Lim, Kah‐Leong, Zhou, Zhi‐Dong, Tan, Eng‐King
Publicado 2016

Towards Selective Mycobacterial ClpP1P2 Inhibitors with Reduced Activity against the Human Proteasome

por Moreira, Wilfried, Santhanakrishnan, Sridhar, Ngan, Grace J. Y., Low, Choon Bing, Sangthongpitag, Kanda, Poulsen, Anders, Dymock, Brian W., Dick, Thomas
Publicado 2017

Local blockade of tacrolimus promotes T-cell-mediated tumor regression in systemically immunosuppressed hosts

por Veitch, Margaret, Beaumont, Kimberly, Pouwer, Rebecca, Chew, Hui Yi, Frazer, Ian H, Soyer, H Peter, Campbell, Scott, Dymock, Brian W, Harvey, Andrew, Cock, Terrie-Anne, Wells, James W
Publicado 2023

Mutation of histone H3 serine 86 disrupts GATA factor Ams2 expression and precise chromosome segregation in fission yeast

por Kiat Lim, Kim, Rui Ong, Terenze Yao, Rong Tan, Yue, Guorong Yang, Eugene, Ren, Bingbing, Shan Seah, Kwi, Yang, Zhe, Soo Tan, Tsu, Dymock, Brian W., Sin Chen, Ee
Publicado 2015

Intracellular Hyper-Acidification Potentiated by Hydrogen Sulfide Mediates Invasive and Therapy Resistant Cancer Cell Death

por Lee, Zheng-Wei, Teo, Xin-Yi, Song, Zhi J., Nin, Dawn S., Novera, Wisna, Choo, Bok A., Dymock, Brian W., Moore, Philip K., Huang, Ruby Y.-J., Deng, Lih-Wen
Publicado 2017

Dual blockade of the lipid kinase PIP4Ks and mitotic pathways leads to cancer-selective lethality

por Kitagawa, Mayumi, Liao, Pei-Ju, Lee, Kyung Hee, Wong, Jasmine, Shang, See Cheng, Minami, Noriaki, Sampetrean, Oltea, Saya, Hideyuki, Lingyun, Dai, Prabhu, Nayana, Diam, Go Ka, Sobota, Radoslaw, Larsson, Andreas, Nordlund, Pär, McCormick, Frank, Ghosh, Sujoy, Epstein, David M., Dymock, Brian W., Lee, Sang Hyun
Publicado 2017