Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors

por Dobrescu, Irina, Hammam, Elie, Dziekan, Jerzy M., Claës, Aurélie, Halby, Ludovic, Preiser, Peter, Bozdech, Zbynek, Arimondo, Paola B., Scherf, Artur, Nardella, Flore
Publicado 2023

Short tandem repeat polymorphism in the promoter region of cyclophilin 19B drives its transcriptional upregulation and contributes to drug resistance in the malaria parasite Plasmo...

por Kucharski, Michal, Wirjanata, Grennady, Nayak, Sourav, Boentoro, Josephine, Dziekan, Jerzy Michal, Assisi, Christina, van der Pluijm, Rob W., Miotto, Olivo, Mok, Sachel, Dondorp, Arjen M., Bozdech, Zbynek
Publicado 2023

Genetic validation of PfFKBP35 as an antimalarial drug target

por Thommen, Basil T, Dziekan, Jerzy M, Achcar, Fiona, Tjia, Seth, Passecker, Armin, Buczak, Katarzyna, Gumpp, Christin, Schmidt, Alexander, Rottmann, Matthias, Grüring, Christof, Marti, Matthias, Bozdech, Zbynek, Brancucci, Nicolas MB
Publicado 2023

Declining Efficacy of Artemisinin Combination Therapy Against P. Falciparum Malaria on the Thai–Myanmar Border (2003–2013): The Role of Parasite Genetic Factors

por Phyo, Aung Pyae, Ashley, Elizabeth A., Anderson, Tim J. C., Bozdech, Zbynek, Carrara, Verena I., Sriprawat, Kanlaya, Nair, Shalini, White, Marina McDew, Dziekan, Jerzy, Ling, Clare, Proux, Stephane, Konghahong, Kamonchanok, Jeeyapant, Atthanee, Woodrow, Charles J., Imwong, Mallika, McGready, Rose, Lwin, Khin Maung, Day, Nicholas P. J., White, Nicholas J., Nosten, Francois
Publicado 2016