The vulnerable primed cancer stem cells in disguise: demystifying the role of Maspin

por Sheng, Shijie, Bernardo, Margarida, Dzinic, Sijana H., Chen, Kang, Sakr, Wael A.
Publicado 2022

The secretion and biological function of tumor suppressor maspin as an exosome cargo protein

por Dean, Ivory, Dzinic, Sijana H, Bernardo, M. Margarida, Zou, Yi, Kimler, Vickie, Li, Xiaohua, Kaplun, Alexander, Granneman, James, Mao, Guangzhao, Sheng, Shijie
Publicado 2016

Identification of an Intrinsic Determinant Critical for Maspin Subcellular Localization and Function

por Dzinic, Sijana H., Kaplun, Alexander, Li, Xiaohua, Bernardo, Margarida, Meng, Yonghong, Dean, Ivory, Krass, David, Stemmer, Paul, Shin, Namhee, Lonardo, Fulvio, Sheng, Shijie
Publicado 2013

Inhibition of CDK9 by voruciclib synergistically enhances cell death induced by the Bcl-2 selective inhibitor venetoclax in preclinical models of acute myeloid leukemia

por Luedtke, Daniel A., Su, Yongwei, Ma, Jun, Li, Xinyu, Buck, Steven A., Edwards, Holly, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Lin, Hai, Taub, Jeffrey W., Ge, Yubin
Publicado 2020

Antileukemic activity and mechanism of action of the novel PI3K and histone deacetylase dual inhibitor CUDC-907 in acute myeloid leukemia

por Li, Xinyu, Su, Yongwei, Madlambayan, Gerard, Edwards, Holly, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Ma, Jun, Knight, Tristan, Wang, Guan, Wang, Yue, Yang, Jay, Taub, Jeffrey W., Lin, Hai, Ge, Yubin
Publicado 2019

Cotargeting of Mitochondrial Complex I and Bcl-2 Shows Antileukemic Activity against Acute Myeloid Leukemia Cells Reliant on Oxidative Phosphorylation

por Liu, Fangbing, Kalpage, Hasini A., Wang, Deying, Edwards, Holly, Hüttemann, Maik, Ma, Jun, Su, Yongwei, Carter, Jenna, Li, Xinyu, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Wang, Guan, Taub, Jeffrey W., Ge, Yubin
Publicado 2020

Maspin differential expression patterns as a potential marker for targeted screening of esophageal adenocarcinoma/gastroesophageal junction adenocarcinoma

por Dzinic, Sijana H., Mahdi, Zaid, Bernardo, M. Margarida, Vranic, Semir, Beydoun, Haya, Nahra, Nadine, Alijagic, Amra, Harajli, Deanna, Pang, Aaron, Saliganan, Dan M., Rahman, Abid M., Skenderi, Faruk, Hasanbegovic, Berisa, Dyson, Gregory, Beydoun, Rafic, Sheng, Shijie
Publicado 2019

The combination of CUDC-907 and gilteritinib shows promising in vitro and in vivo antileukemic activity against FLT3-ITD AML

por Qiao, Xinan, Ma, Jun, Knight, Tristan, Su, Yongwei, Edwards, Holly, Polin, Lisa, Li, Jing, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Wang, Jian, Lin, Hai, Wang, Yue, Wang, Liping, Wang, Guan, Taub, Jeffrey W., Ge, Yubin
Publicado 2021

Targeted therapy of pyrrolo[2,3-d]pyrimidine antifolates in a syngeneic mouse model of high grade serous ovarian cancer and the impact on the tumor microenvironment

por Wallace-Povirk, Adrianne, Rubinsak, Lisa, Malysa, Agnes, Dzinic, Sijana H., Ravindra, Manasa, Schneider, Mathew, Glassbrook, James, O’Connor, Carrie, Hou, Zhanjun, Kim, Seongho, Back, Jessica, Polin, Lisa, Morris, Robert T., Gangjee, Aleem, Gibson, Heather, Matherly, Larry H.
Publicado 2022

The HDAC and PI3K dual inhibitor CUDC-907 synergistically enhances the antileukemic activity of venetoclax in preclinical models of acute myeloid leukemia

por Li, Xinyu, Su, Yongwei, Hege, Katie, Madlambayan, Gerard, Edwards, Holly, Knight, Tristan, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Yang, Jay, Miller, Regan, Wang, Guan, Zhao, Lijing, Wang, Yue, Lin, Hai, Taub, Jeffrey W., Ge, Yubin
Publicado 2020

Maspin expression in prostate tumor elicits host anti-tumor immunity

por Dzinic, Sijana H., Chen, Kang, Thakur, Archana, Kaplun, Alexander, Daniel Bonfil, R., Li, Xiaohua, Liu, Jason, Margarida Bernardo, M., Saliganan, Allen, Back, Jessica B., Yano, Hiroshi, Schalk, Dana L., Tomaszewski, Elyse N., Beydoun, Ahmed S., Dyson, Gregory, Mujagic, Adelina, Krass, David, Dean, Ivory, Mi, Qing-Sheng, Heath, Elisabeth, Sakr, Wael, Lum, Lawrence G., Sheng, Shijie
Publicado 2014

Enhancing anti-AML activity of venetoclax by isoflavone ME-344 through suppression of OXPHOS and/or purine biosynthesis

por Hurrish, Katie H., Su, Yongwei, Patel, Shraddha, Ramage, Cassandra L, Carter, Jenna L., Edwards, Holly, Buck, Steven A., Wiley, Sandra E., Hüttemann, Maik, Polin, Lisa, Kushner, Juiwanna, Dzinic, Sijana H., White, Kathryn, Bao, Xun, Li, Jing, Yang, Jay, Boerner, Julie, Hou, Zhanjun, Al-Atrash, Gheath, Konoplev, Sergej N, Busquets, Jonathan, Tiziani, Stefano, Matherly, Larry H., Taub, Jeffrey W., Konopleva, Marina, Ge, Yubin, Baran, Natalia
Publicado 2023