The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer

por Abel, Ethan V., Kim, Edward J., Wu, Jingjiang, Hynes, Mark, Bednar, Filip, Proctor, Erica, Wang, Lidong, Dziubinski, Michele L., Simeone, Diane M.
Publicado 2014

Usp9x Promotes Survival in Human Pancreatic Cancer and Its Inhibition Suppresses Pancreatic Ductal Adenocarcinoma In Vivo Tumor Growth()

por Pal, Anupama, Dziubinski, Michele, Di Magliano, Marina Pasca, Simeone, Diane M., Owens, Scott, Thomas, Dafydd, Peterson, Luke, Potu, Harish, Talpaz, Moshe, Donato, Nicholas J.
Publicado 2017

miR-181a initiates and perpetuates oncogenic transformation through the regulation of innate immune signaling

por Knarr, Matthew, Avelar, Rita A., Sekhar, Sreeja C., Kwiatkowski, Lily J., Dziubinski, Michele L., McAnulty, Jessica, Skala, Stephanie, Avril, Stefanie, Drapkin, Ronny, DiFeo, Analisa
Publicado 2020

HNF1A is a novel oncogene that regulates human pancreatic cancer stem cell properties

por Abel, Ethan V, Goto, Masashi, Magnuson, Brian, Abraham, Saji, Ramanathan, Nikita, Hotaling, Emily, Alaniz, Anthony A, Kumar-Sinha, Chandan, Dziubinski, Michele L, Urs, Sumithra, Wang, Lidong, Shi, Jiaqi, Waghray, Meghna, Ljungman, Mats, Crawford, Howard C, Simeone, Diane M
Publicado 2018

ATDC Mediates a TP63-Regulated Basal Cancer Invasive Program

por Palmbos, Phillip L., Wang, Yin, Bankhead, Armand, Kelleher, Alan J., Wang, Lidong, Yang, Huibin, Ahmet, McKenzie L., Gumkowski, Erica R., Welling, Samuel D., Magnuson, Brian, Leflein, Jacob, Hiles, Guadalupe Lorenzatti, Abel, Ethan, Dziubinski, Michele L., Urs, Sumithra, Day, Mark, Ljungman, Mats E., Simeone, Diane M.
Publicado 2019

Small-Molecule–Mediated Stabilization of PP2A Modulates the Homologous Recombination Pathway and Potentiates DNA Damage-Induced Cell Death

por Avelar, Rita A., Armstrong, Amy J., Carvette, Gracie, Gupta, Riya, Puleo, Noah, Colina, Jose A., Joseph, Peronne, Sobeck, Alexander M., O'Connor, Caitlin M., Raines, Brynne, Gandhi, Agharnan, Dziubinski, Michele L., Ma, Daniel S., Resnick, Kimberly, Singh, Sareena, Zanotti, Kristine, Nagel, Christa, Waggoner, Steven, Thomas, Daffyd G., Skala, Stephanie L., Zhang, Junran, Narla, Goutham, DiFeo, Analisa
Publicado 2023

HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

por Brunton, Holly, Caligiuri, Giuseppina, Cunningham, Richard, Upstill-Goddard, Rosie, Bailey, Ulla-Maja, Garner, Ian M., Nourse, Craig, Dreyer, Stephan, Jones, Marc, Moran-Jones, Kim, Wright, Derek W., Paulus-Hock, Viola, Nixon, Colin, Thomson, Gemma, Jamieson, Nigel B., McGregor, Grant A., Evers, Lisa, McKay, Colin J., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephen J., Dziubinski, Michele L., Barry, Simon T., Grützmann, Robert, Brown, Robert, Curry, Edward, Pajic, Marina, Musgrove, Elizabeth A., Petersen, Gloria M., Shanks, Emma, Ashworth, Alan, Crawford, Howard C., Simeone, Diane M., Froeling, Fieke E.M., Lord, Christopher J., Mukhopadhyay, Debabrata, Pilarsky, Christian, Grimmond, Sean E., Morton, Jennifer P., Sansom, Owen J., Chang, David K., Bailey, Peter J., Biankin, Andrew V.
Publicado 2020

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

por Dreyer, Stephan B., Upstill-Goddard, Rosie, Paulus-Hock, Viola, Paris, Clara, Lampraki, Eirini-Maria, Dray, Eloise, Serrels, Bryan, Caligiuri, Giuseppina, Rebus, Selma, Plenker, Dennis, Galluzzo, Zachary, Brunton, Holly, Cunningham, Richard, Tesson, Mathias, Nourse, Craig, Bailey, Ulla-Maja, Jones, Marc, Moran-Jones, Kim, Wright, Derek W., Duthie, Fraser, Oien, Karin, Evers, Lisa, McKay, Colin J., McGregor, Grant A., Gulati, Aditi, Brough, Rachel, Bajrami, Ilirjana, Pettitt, Stephan, Dziubinski, Michele L., Candido, Juliana, Balkwill, Frances, Barry, Simon T., Grützmann, Robert, Rahib, Lola, Johns, Amber, Pajic, Marina, Froeling, Fieke E.M., Beer, Phillip, Musgrove, Elizabeth A., Petersen, Gloria M., Ashworth, Alan, Frame, Margaret C., Crawford, Howard C., Simeone, Diane M., Lord, Chris, Mukhopadhyay, Debabrata, Pilarsky, Christian, Tuveson, David A., Cooke, Susanna L., Jamieson, Nigel B., Morton, Jennifer P., Sansom, Owen J., Bailey, Peter J., Biankin, Andrew V., Chang, David K.
Publicado 2021