The combination of manogepix and itraconazole is synergistic and inhibits the growth of Madurella mycetomatis in vitro but not in vivo

por Konings, Mickey, Eadie, Kimberly, Strepis, Nikolaos, Nyuykonge, Bertrand, Fahal, Ahmed H, Verbon, Annelies, van de Sande, Wendy W J
Publicado 2023

The synthetic synergistic cinnamon oil CIN-102 is active against Madurella mycetomatis, the most common causative agent of mycetoma

por Konings, Mickey, Eadie, Kimberly, Lim, Wilson, Fahal, Ahmed H., Mouton, Johan, Tesse, Nicolas, van de Sande, Wendy W. J.
Publicado 2021

Inhibiting DHN- and DOPA-melanin biosynthesis pathway increased the therapeutic value of itraconazole in Madurella mycetomatis infected Galleria mellonella

por Lim, Wilson, Konings, Mickey, Parel, Florianne, Eadie, Kimberly, Strepis, Nikolaos, Fahal, Ahmed, Verbon, Annelies, van de Sande, Wendy W J
Publicado 2022

A Polymorphism in the Chitotriosidase Gene Associated with Risk of Mycetoma Due to Madurella mycetomatis Mycetoma–A Retrospective Study

por Verwer, Patricia E. B., Notenboom, Charlotte C., Eadie, Kimberly, Fahal, Ahmed H., Verbrugh, Henri A., van de Sande, Wendy W. J.
Publicado 2015

The development of a novel diagnostic PCR for Madurella mycetomatis using a comparative genome approach

por Lim, Wilson, Siddig, Emmanuel, Eadie, Kimberly, Nyuykonge, Bertrand, Ahmed, Sarah, Fahal, Ahmed, Verbon, Annelies, Smit, Sandra, van de Sande, Wendy WJ
Publicado 2020

Madurella mycetomatis, the main causative agent of eumycetoma, is highly susceptible to olorofim

por Lim, Wilson, Eadie, Kimberly, Konings, Mickey, Rijnders, Bart, Fahal, Ahmed H, Oliver, Jason D, Birch, Mike, Verbon, Annelies, van de Sande, Wendy
Publicado 2020

Double-Stranded RNA Mycovirus Infection of Aspergillus fumigatus Is Not Dependent on the Genetic Make-Up of the Host

por Refos, Jeannine M., Vonk, Alieke G., Eadie, Kimberly, Lo-Ten-Foe, Jerome R., Verbrugh, Henri A., van Diepeningen, Anne D., van de Sande, Wendy W. J.
Publicado 2013

Addition of 17-(allylamino)-17-demethoxygeldanamycin to a suboptimal caspofungin treatment regimen in neutropenic rats with invasive pulmonary aspergillosis delays the time to deat...

por Refos, Jeannine M., Vonk, Alieke G., ten Kate, Marian T., Eadie, Kimberly, Verbrugh, Henri A., Bakker-Woudenberg, Irma A. J. M., van de Sande, Wendy W. J.
Publicado 2017

Addressing the most neglected diseases through an open research model: The discovery of fenarimols as novel drug candidates for eumycetoma

por Lim, Wilson, Melse, Youri, Konings, Mickey, Phat Duong, Hung, Eadie, Kimberly, Laleu, Benoît, Perry, Benjamin, Todd, Matthew H., Ioset, Jean-Robert, van de Sande, Wendy W. J.
Publicado 2018

Screening the pandemic response box identified benzimidazole carbamates, Olorofim and ravuconazole as promising drug candidates for the treatment of eumycetoma

por Lim, Wilson, Nyuykonge, Bertrand, Eadie, Kimberly, Konings, Mickey, Smeets, Juli, Fahal, Ahmed, Bonifaz, Alexandro, Todd, Matthew, Perry, Benjamin, Samby, Kirandeep, Burrows, Jeremy, Verbon, Annelies, van de Sande, Wendy
Publicado 2022