Generating Robust and Informative Nonclinical In Vitro and In Vivo Bacterial Infection Model Efficacy Data To Support Translation to Humans

por Bulitta, Jürgen B., Hope, William W., Eakin, Ann E., Guina, Tina, Tam, Vincent H., Louie, Arnold, Drusano, George L., Hoover, Jennifer L.
Publicado 2019

Key Substitutions in the Spike Protein of SARS-CoV-2 Variants Can Predict Resistance to Monoclonal Antibodies, but Other Substitutions Can Modify the Effects

por Lusvarghi, Sabrina, Wang, Wei, Herrup, Rachel, Neerukonda, Sabari Nath, Vassell, Russell, Bentley, Lisa, Eakin, Ann E., Erlandson, Karl J., Weiss, Carol D.
Publicado 2022

SARS-CoV-2 Delta Variant Displays Moderate Resistance to Neutralizing Antibodies and Spike Protein Properties of Higher Soluble ACE2 Sensitivity, Enhanced Cleavage and Fusogenic Ac...

por Neerukonda, Sabari Nath, Vassell, Russell, Lusvarghi, Sabrina, Wang, Richard, Echegaray, Fernando, Bentley, Lisa, Eakin, Ann E., Erlandson, Karl J., Katzelnick, Leah C., Weiss, Carol D., Wang, Wei
Publicado 2021

In Vivo Activity of Amodiaquine against Ebola Virus Infection

por DeWald, Lisa Evans, Johnson, Joshua C., Gerhardt, Dawn M., Torzewski, Lisa M., Postnikova, Elena, Honko, Anna N., Janosko, Krisztina, Huzella, Louis, Dowling, William E., Eakin, Ann E., Osborn, Blaire L., Gahagen, Janet, Tang, Liang, Green, Carol E., Mirsalis, Jon C., Holbrook, Michael R., Jahrling, Peter B., Dyall, Julie, Hensley, Lisa E.
Publicado 2019

Evaluation of a panel of therapeutic antibody clinical candidates for efficacy against SARS-CoV-2 in Syrian hamsters

por Cong, Yu, Mucker, Eric M., Perry, Donna L., Dixit, Saurabh, Kollins, Erin, Byrum, Russ, Huzella, Louis, Kim, Robert, Josleyn, Mathew, Kwilas, Steven, Stefan, Christopher, Shoemaker, Charles J., Koehler, Jeff, Coyne, Susan, Delp, Korey, Liang, Janie, Drawbaugh, David, Hischak, Amanda, Hart, Randy, Postnikova, Elena, Vaughan, Nick, Asher, Jason, St Claire, Marisa, Hanson, Jarod, Schmaljohn, Connie, Eakin, Ann E., Hooper, Jay W., Holbrook, Michael R.
Publicado 2023

SARS-CoV-2 Omicron neutralization by therapeutic antibodies, convalescent sera, and post-mRNA vaccine booster

por Lusvarghi, Sabrina, Pollett, Simon D., Neerukonda, Sabari Nath, Wang, Wei, Wang, Richard, Vassell, Russell, Epsi, Nusrat J., Fries, Anthony C, Agan, Brian K, Lindholm, David A., Colombo, Christopher J., Mody, Rupal, Ewers, Evan C., Lalani, Tahaniyat, Ganesan, Anuradha, Goguet, Emilie, Hollis-Perry, Monique, Coggins, Si’Ana A., Simons, Mark P., Katzelnick, Leah C., Wang, Gregory, Tribble, David R., Bentley, Lisa, Eakin, Ann E., Broder, Christopher C., Erlandson, Karl J., Laing, Eric D., Burgess, Timothy H., Mitre, Edward, Weiss, Carol D.
Publicado 2021

SARS-CoV-2 BA.1 variant is neutralized by vaccine booster-elicited serum, but evades most convalescent serum and therapeutic antibodies

por Lusvarghi, Sabrina, Pollett, Simon D., Neerukonda, Sabari Nath, Wang, Wei, Wang, Richard, Vassell, Russell, Epsi, Nusrat J., Fries, Anthony C., Agan, Brian K., Lindholm, David A., Colombo, Christopher J., Mody, Rupal, Ewers, Evan C., Lalani, Tahaniyat, Ganesan, Anuradha, Goguet, Emilie, Hollis-Perry, Monique, Coggins, Si’Ana A., Simons, Mark P., Katzelnick, Leah C., Wang, Gregory, Tribble, David R., Bentley, Lisa, Eakin, Ann E., Broder, Christopher C., Erlandson, Karl J., Laing, Eric D., Burgess, Timothy H., Mitre, Edward, Weiss, Carol D.
Publicado 2022

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus

por Cong, Yu, Dyall, Julie, Hart, Brit J., DeWald, Lisa Evans, Johnson, Joshua C., Postnikova, Elena, Zhou, Huanying, Gross, Robin, Rojas, Oscar, Alexander, Isis, Josleyn, Nicole, Zhang, Tengfei, Michelotti, Julia, Janosko, Krisztina, Glass, Pamela J., Flint, Mike, McMullan, Laura K., Spiropoulou, Christina F., Mierzwa, Tim, Guha, Rajarshi, Shinn, Paul, Michael, Sam, Klumpp-Thomas, Carleen, McKnight, Crystal, Thomas, Craig, Eakin, Ann E., O’Loughlin, Kathleen G., Green, Carol E., Catz, Paul, Mirsalis, Jon C., Honko, Anna N., Olinger, Gene G., Bennett, Richard S., Holbrook, Michael R., Hensley, Lisa E., Jahrling, Peter B.
Publicado 2016