A critical role for IRF5 in regulating allergic airway inflammation

por Byrne, Adam J., Weiss, Miriam, Mathie, Sara A., Walker, Simone A., Eames, Hayley L., Saliba, David, Lloyd, Clare M., Udalova, Irina A.
Publicado 2016

IFN-λ resolves inflammation via suppression of neutrophil infiltration and IL-1β production

por Blazek, Katrina, Eames, Hayley L., Weiss, Miriam, Byrne, Adam J., Perocheau, Dany, Pease, James E., Doyle, Sean, McCann, Fiona, Williams, Richard O., Udalova, Irina A.
Publicado 2015

Macrophages in the synovial lining niche initiate neutrophil recruitment and articular inflammation

por Zec, Kristina, Schonfeldova, Barbora, Ai, Zhichao, Van Grinsven, Erinke, Pirgova, Gabriela, Eames, Hayley L., Berthold, Dorothée L., Attar, Moustafa, Compeer, Ewoud B., Arnon, Tal I., Udalova, Irina A.
Publicado 2023

Antibody response to homologous epitopes of Epstein-Barr virus, Mycobacterium avium subsp. paratuberculosis and IRF5 in patients with different connective tissue diseases and in mo...

por Bo, Marco, Niegowska, Magdalena, Eames, Hayley L., Almuttaqi, Hannah, Arru, Giannina, Erre, Gian Luca, Passiu, Giuseppe, Khoyratty, Tariq E., van Grinsven, Erinke, Udalova, Irina A., Sechi, Leonardo A.
Publicado 2020

ROS-producing immature neutrophils in giant cell arteritis are linked to vascular pathologies

por Wang, Lihui, Ai, Zhichao, Khoyratty, Tariq, Zec, Kristina, Eames, Hayley L., van Grinsven, Erinke, Hudak, Alison, Morris, Susan, Ahern, David, Monaco, Claudia, Eruslanov, Evgeniy B., Luqmani, Raashid, Udalova, Irina A.
Publicado 2020

IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages

por Saliba, David G., Heger, Andreas, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam, Pasparakis, Manolis, Ragoussis, Jiannis, Udalova, Irina A.
Publicado 2014

Distinct transcription factor networks control neutrophil-driven inflammation

por Khoyratty, Tariq E, Ai, Zhichao, Ballesteros, Ivan, Eames, Hayley L, Mathie, Sara, Martín-Salamanca, Sandra, Wang, Lihui, Hemmings, Ashleigh, Willemsen, Nicola, von Werz, Valentin, Zehrer, Annette, Walzog, Barbara, van Grinsven, Erinke, Hidalgo, Andres, Udalova, Irina A
Publicado 2021

Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation

por Ryzhakov, Grigory, Almuttaqi, Hannah, Corbin, Alastair L., Berthold, Dorothée L., Khoyratty, Tariq, Eames, Hayley L., Bullers, Samuel, Pearson, Claire, Ai, Zhichao, Zec, Kristina, Bonham, Sarah, Fischer, Roman, Jostins-Dean, Luke, Travis, Simon P. L., Kessler, Benedikt M., Udalova, Irina A.
Publicado 2021