Targeting MERTK and AXL in EGFR Mutant Non-Small Cell Lung Cancer

por Yan, Dan, Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K.
Publicado 2021

Epithelial cell-directed efferocytosis in the post-partum mammary gland is necessary for tissue homeostasis and future lactation

por Sandahl, Melissa, Hunter, Debra M, Strunk, Karen E, Earp, H Shelton, Cook, Rebecca S
Publicado 2010

Dasatinib inhibits site-specific tyrosine phosphorylation of androgen receptor by Ack1 and Src kinases

por Liu, Yuanbo, Karaca, Mehmet, Zhang, Zhentao, Gioeli, Daniel, Earp, H. Shelton, Whang, Young E.
Publicado 2010

Targeting the TAM Receptors in Leukemia

por Huey, Madeline G., Minson, Katherine A., Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K.
Publicado 2016

Mutation of Androgen Receptor N-Terminal Phosphorylation Site Tyr-267 Leads to Inhibition of Nuclear Translocation and DNA Binding

por Karaca, Mehmet, Liu, Yuanbo, Zhang, Zhentao, De Silva, Dinuka, Parker, Joel S., Earp, H. Shelton, Whang, Young E.
Publicado 2015

The role of endothelial MERTK during the inflammatory response in lungs

por Li, Yitong, Wittchen, Erika S., Monaghan-Benson, Elizabeth, Hahn, Cornelia, Earp, H. Shelton, Doerschuk, Claire M., Burridge, Keith
Publicado 2019

A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation

por Wang, Jun, Park, Kwang-Su, Yu, Xufen, Gong, Weida, Earp, H Shelton, Wang, Gang Greg, Jin, Jian, Cai, Ling
Publicado 2022

Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen

por De Silva, Dinuka, Zhang, Zhentao, Liu, Yuanbo, Parker, Joel S., Xu, Chenxi, Cai, Ling, Wang, Gang Greg, Earp, H. Shelton, Whang, Young E.
Publicado 2019

Inherited predisposition to breast cancer in the Carolina Breast Cancer Study

por Walsh, Tom, Gulsuner, Suleyman, Lee, Ming K., Troester, Melissa A., Olshan, Andrew F., Earp, H. Shelton, Perou, Charles M., King, Mary-Claire
Publicado 2021

TNK2/ACK1-mediated phosphorylation of ATP5F1A (ATP synthase F1 subunit alpha) selectively augments survival of prostate cancer while engendering mitochondrial vulnerability

por Chouhan, Surbhi, Sawant, Mithila, Weimholt, Cody, Luo, Jingqin, Sprung, Robert W., Terrado, Mailyn, Mueller, David M., Earp, H. Shelton, Mahajan, Nupam P.
Publicado 2022

Delayed Apoptotic Cell Clearance and Lupus-like Autoimmunity in Mice Lacking the c-mer Membrane Tyrosine Kinase

por Cohen, Philip L., Caricchio, Roberto, Abraham, Valsamma, Camenisch, Todd D., Jennette, J. Charles, Roubey, Robert A.S., Earp, H. Shelton, Matsushima, Glenn, Reap, Elizabeth A.
Publicado 2002

MerTK is required for apoptotic cell–induced T cell tolerance

por Wallet, Mark A., Sen, Pradip, Flores, Rafael R., Wang, Yaming, Yi, Zuoan, Huang, Yingsu, Mathews, Clayton E., Earp, H. Shelton, Matsushima, Glenn, Wang, Bo, Tisch, Roland
Publicado 2008

Mer590, a novel monoclonal antibody targeting MER receptor tyrosine kinase, decreases colony formation and increases chemosensitivity in non-small cell lung cancer

por Cummings, Christopher T., Linger, Rachel M.A., Cohen, Rebecca A., Sather, Susan, Kirkpatrick, Gregory D., Davies, Kurtis D., DeRyckere, Deborah, Earp, H. Shelton, Graham, Douglas K.
Publicado 2014

Inhibiting efferocytosis reverses macrophage-mediated immunosuppression in the leukemia microenvironment

por Cruz Cruz, Joselyn, Allison, Kristen C., Page, Lauren S., Jenkins, Alexis J., Wang, Xiaodong, Earp, H. Shelton, Frye, Stephen V., Graham, Douglas K., Verneris, Michael R., Lee-Sherick, Alisa B.
Publicado 2023

MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme

por Sufit, Alexandra, Lee-Sherick, Alisa B., DeRyckere, Deborah, Rupji, Manali, Dwivedi, Bhakti, Varella-Garcia, Marileila, Pierce, Angela M., Kowalski, Jeanne, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Keating, Amy K., Graham, Douglas K.
Publicado 2016

MERTK activation drives osimertinib resistance in EGFR-mutant non–small cell lung cancer

por Yan, Dan, Huelse, Justus M., Kireev, Dmitri, Tan, Zikang, Chen, Luxiao, Goyal, Subir, Wang, Xiaodong, Frye, Stephen V., Behera, Madhusmita, Schneider, Frank, Ramalingam, Suresh S., Owonikoko, Taofeek, Earp, H. Shelton, DeRyckere, Deborah, Graham, Douglas K.
Publicado 2022

MERTK inhibition alters the PD-1 axis and promotes anti-leukemia immunity

por Lee-Sherick, Alisa B., Jacobsen, Kristen M., Henry, Curtis J., Huey, Madeline G., Parker, Rebecca E., Page, Lauren S., Hill, Amanda A., Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Jordan, Craig T., DeRyckere, Deborah, Graham, Douglas K.
Publicado 2020

Therapeutic Targeting of MERTK and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia

por Summers, Ryan J., Jain, Juhi, Vasileiadi, Eleana, Smith, Brittany, Chimenti, Madison L., Yeung, Tsz Y., Kelvin, James, Wang, Xiaodong, Frye, Stephen V., Earp, H. Shelton, Tyner, Jeffrey W., Dreaden, Erik C., DeRyckere, Deborah, Graham, Douglas K.
Publicado 2022

Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia

por Lee-Sherick, A B, Eisenman, K M, Sather, S, McGranahan, A, Armistead, P M, McGary, C S, Hunsucker, S A, Schlegel, J, Martinson, H, Cannon, C, Keating, A K, Earp, H S, Liang, X, DeRyckere, D, Graham, D K
Publicado 2013

Erratum: Aberrant Mer receptor tyrosine kinase expression contributes to leukemogenesis in acute myeloid leukemia

por Lee-Sherick, A B, Eisenman, K M, Sather, S, McGranahan, A, Armistead, P M, McGary, C S, Hunsucker, S A, Schlegel, J, Martinson, H, Cannon, C, Keating, A K, Earp, H S, Liang, X, DeRyckere, D, Graham, D K
Publicado 2016