Sialylation of Campylobacter jejuni Lipo-Oligosaccharides: Impact on Phagocytosis and Cytokine Production in Mice

por Huizinga, Ruth, Easton, Alistair S., Donachie, Anne M., Guthrie, Jim, van Rijs, Wouter, Heikema, Astrid, Boon, Louis, Samsom, Janneke N., Jacobs, Bart C., Willison, Hugh J., Goodyear, Carl S.
Publicado 2012

Pharmacological Inhibition of ATR Can Block Autophagy through an ATR-Independent Mechanism

por Bowler, Elizabeth, Skwarska, Anna, Wilson, Joseph D., Ramachandran, Shaliny, Bolland, Hannah, Easton, Alistair, Ostheimer, Christian, Hwang, Ming-Shih, Leszczynska, Katarzyna B., Conway, Stuart J., Hammond, Ester M.
Publicado 2020

Cyclophosphamide depletes tumor infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma

por Webb, Emily R., Moreno-Vincente, Julia, Easton, Alistair, Lanati, Silvia, Taylor, Martin, James, Sonya, Williams, Emily L., English, Vikki, Penfold, Chris, Beers, Stephen A., Gray, Juliet C.
Publicado 2022

Immune characterization of pre-clinical murine models of neuroblastoma

por Webb, Emily R., Lanati, Silvia, Wareham, Carol, Easton, Alistair, Dunn, Stuart N., Inzhelevskaya, Tatyana, Sadler, Freja M., James, Sonya, Ashton-Key, Margaret, Cragg, Mark S., Beers, Stephen A., Gray, Juliet C.
Publicado 2020

Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer

por Sivakumar, Shivan, Abu-Shah, Enas, Ahern, David J., Arbe-Barnes, Edward H., Jainarayanan, Ashwin K., Mangal, Nagina, Reddy, Srikanth, Rendek, Aniko, Easton, Alistair, Kurz, Elke, Silva, Michael, Soonawalla, Zahir, Heij, Lara R., Bashford-Rogers, Rachael, Middleton, Mark R., Dustin, Michael L.
Publicado 2021

The Novel Nucleoside Analogue ProTide NUC-7738 Overcomes Cancer Resistance Mechanisms In Vitro and in a First-In-Human Phase I Clinical Trial

por Schwenzer, Hagen, De Zan, Erica, Elshani, Mustafa, van Stiphout, Ruud, Kudsy, Mary, Morris, Josephine, Ferrari, Valentina, Um, In Hwa, Chettle, James, Kazmi, Farasat, Campo, Leticia, Easton, Alistair, Nijman, Sebastian, Serpi, Michaela, Symeonides, Stefan, Plummer, Ruth, Harrison, David J., Bond, Gareth, Blagden, Sarah P.
Publicado 2021

Interferon-Gamma–Producing CD8(+) Tissue Resident Memory T Cells Are a Targetable Hallmark of Immune Checkpoint Inhibitor–Colitis

por Sasson, Sarah C., Slevin, Stephanie M., Cheung, Vincent T.F., Nassiri, Isar, Olsson-Brown, Anna, Fryer, Eve, Ferreira, Ricardo C., Trzupek, Dominik, Gupta, Tarun, Al-Hillawi, Lulia, Issaias, Mari-lenna, Easton, Alistair, Campo, Leticia, FitzPatrick, Michael E.B., Adams, Joss, Chitnis, Meenali, Protheroe, Andrew, Tuthill, Mark, Coupe, Nicholas, Simmons, Alison, Payne, Miranda, Middleton, Mark R., Travis, Simon P.L., Fairfax, Benjamin P., Klenerman, Paul, Brain, Oliver
Publicado 2021

IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies

por Friedrich, Matthias, Pohin, Mathilde, Jackson, Matthew A., Korsunsky, Ilya, Bullers, Samuel J., Rue-Albrecht, Kevin, Christoforidou, Zoe, Sathananthan, Dharshan, Thomas, Tom, Ravindran, Rahul, Tandon, Ruchi, Peres, Raphael Sanches, Sharpe, Hannah, Wei, Kevin, Watts, Gerald F. M., Mann, Elizabeth H., Geremia, Alessandra, Attar, Moustafa, McCuaig, Sarah, Thomas, Lloyd, Collantes, Elena, Uhlig, Holm H., Sansom, Stephen N., Easton, Alistair, Raychaudhuri, Soumya, Travis, Simon P., Powrie, Fiona M.
Publicado 2021

Cervical lymph nodes and ovarian teratomas as germinal centres in NMDA receptor-antibody encephalitis

por Al-Diwani, Adam, Theorell, Jakob, Damato, Valentina, Bull, Joshua, McGlashan, Nicholas, Green, Edward, Kienzler, Anne Kathrin, Harrison, Ruby, Hassanali, Tasneem, Campo, Leticia, Browne, Molly, Easton, Alistair, Soleymani majd, Hooman, Tenaka, Keiko, Iorio, Raffaele, Dale, Russell C, Harrison, Paul, Geddes, John, Quested, Digby, Sharp, David, Lee, Soon Tae, Nauen, David W, Makuch, Mateusz, Lennox, Belinda, Fowler, Darren, Sheerin, Fintan, Waters, Patrick, Leite, M Isabel, Handel, Adam E, Irani, Sarosh R
Publicado 2022

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

por Gil Vazquez, Ester, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.
Publicado 2022

Dynamic and adaptive cancer stem cell population admixture in colorectal neoplasia

por Gil Vazquez, Ester, Nasreddin, Nadia, Valbuena, Gabriel N., Mulholland, Eoghan J., Belnoue-Davis, Hayley L., Eggington, Holly R., Schenck, Ryan O., Wouters, Valérie M., Wirapati, Pratyaksha, Gilroy, Kathryn, Lannagan, Tamsin R.M., Flanagan, Dustin J., Najumudeen, Arafath K., Omwenga, Sulochana, McCorry, Amy M.B., Easton, Alistair, Koelzer, Viktor H., East, James E., Morton, Dion, Trusolino, Livio, Maughan, Timothy, Campbell, Andrew D., Loughrey, Maurice B., Dunne, Philip D., Tsantoulis, Petros, Huels, David J., Tejpar, Sabine, Sansom, Owen J., Leedham, Simon J.
Publicado 2022

Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1

por Beach, Callum, MacLean, David, Majorova, Dominika, Melemenidis, Stavros, Nambiar, Dhanya K., Kim, Ryan K., Valbuena, Gabriel N., Guglietta, Silvia, Krieg, Carsten, Darvish-Damavandi, Mahnaz, Suwa, Tatsuya, Easton, Alistair, Hillson, Lily V.S., McCulloch, Ashley K., McMahon, Ross K., Pennel, Kathryn, Edwards, Joanne, O’Cathail, Sean M., Roxburgh, Campbell S., Domingo, Enric, Moon, Eui Jung, Jiang, Dadi, Jiang, Yanyan, Zhang, Qingyang, Koong, Albert C., Woodruff, Trent M., Graves, Edward E., Maughan, Tim, Buczacki, Simon J.A., Stucki, Manuel, Le, Quynh-Thu, Leedham, Simon J., Giaccia, Amato J., Olcina, Monica M.
Publicado 2023