Use of mRNA expression signatures to discover small molecule inhibitors of skeletal muscle atrophy

por Adams, Christopher M., Ebert, Scott M., Dyle, Michael C.
Publicado 2015

Ursolic Acid Increases Skeletal Muscle and Brown Fat and Decreases Diet-Induced Obesity, Glucose Intolerance and Fatty Liver Disease

por Kunkel, Steven D., Elmore, Christopher J., Bongers, Kale S., Ebert, Scott M., Fox, Daniel K., Dyle, Michael C., Bullard, Steven A., Adams, Christopher M.
Publicado 2012

Systems-based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy

por Dyle, Michael C., Ebert, Scott M., Cook, Daniel P., Kunkel, Steven D., Fox, Daniel K., Bongers, Kale S., Bullard, Steven A., Dierdorff, Jason M., Adams, Christopher M.
Publicado 2014

Gadd45a Protein Promotes Skeletal Muscle Atrophy by Forming a Complex with the Protein Kinase MEKK4

por Bullard, Steven A., Seo, Seongjin, Schilling, Birgit, Dyle, Michael C., Dierdorff, Jason M., Ebert, Scott M., DeLau, Austin D., Gibson, Bradford W., Adams, Christopher M.
Publicado 2016

Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy

por Ebert, Scott M., Dyle, Michael C., Bullard, Steven A., Dierdorff, Jason M., Murry, Daryl J., Fox, Daniel K., Bongers, Kale S., Lira, Vitor A., Meyerholz, David K., Talley, John J., Adams, Christopher M.
Publicado 2015

Activating transcription factor 4 (ATF4) promotes skeletal muscle atrophy by forming a heterodimer with the transcriptional regulator C/EBPβ

por Ebert, Scott M., Bullard, Steven A., Basisty, Nathan, Marcotte, George R., Skopec, Zachary P., Dierdorff, Jason M., Al-Zougbi, Asma, Tomcheck, Kristin C., DeLau, Austin D., Rathmacher, Jacob A., Bodine, Sue C., Schilling, Birgit, Adams, Christopher M.
Publicado 2020

The transcription regulator ATF4 is a mediator of skeletal muscle aging

por Miller, Matthew J., Marcotte, George R., Basisty, Nathan, Wehrfritz, Cameron, Ryan, Zachary C., Strub, Matthew D., McKeen, Andrew T., Stern, Jennifer I., Nath, Karl A., Rasmussen, Blake B., Judge, Andrew R., Schilling, Birgit, Ebert, Scott M., Adams, Christopher M.
Publicado 2023

ULK2 is essential for degradation of ubiquitinated protein aggregates and homeostasis in skeletal muscle

por Fuqua, Jordan D., Mere, Caleb P., Kronemberger, Ana, Blomme, Jay, Bae, Dam, Turner, Kristen D., Harris, Matthew P., Scudese, Estevão, Edwards, Mitchell, Ebert, Scott M., de Sousa, Luís G. O., Bodine, Sue C., Yang, Ling, Adams, Christopher M., Lira, Vitor A.
Publicado 2019