Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones

por Karademir, Duygu, Todorova, Vyara, Ebner, Lynn J. A., Samardzija, Marijana, Grimm, Christian
Publicado 2022

Evaluation of Two Liver Treatment Strategies in a Mouse Model of Niemann–Pick-Disease Type C1

por Ebner, Lynn, Gläser, Anne, Bräuer, Anja, Witt, Martin, Wree, Andreas, Rolfs, Arndt, Frank, Marcus, Vollmar, Brigitte, Kuhla, Angela
Publicado 2018

Regulation of ABCA1 by AMD-Associated Genetic Variants and Hypoxia in iPSC-RPE

por Peters, Florian, Ebner, Lynn J. A., Atac, David, Maggi, Jordi, Berger, Wolfgang, den Hollander, Anneke I., Grimm, Christian
Publicado 2022

Mouse Retinal Organoid Growth and Maintenance in Longer-Term Culture

por Völkner, Manuela, Kurth, Thomas, Schor, Jana, Ebner, Lynn J. A., Bardtke, Lara, Kavak, Cagri, Hackermüller, Jörg, Karl, Mike O.
Publicado 2021

Retinal Layer Separation (ReLayS) method enables the molecular analysis of photoreceptor segments and cell bodies, as well as the inner retina

por Todorova, Vyara, Merolla, Luca, Karademir, Duygu, Wögenstein, Gabriele M., Behr, Julian, Ebner, Lynn J. A., Samardzija, Marijana, Grimm, Christian
Publicado 2022

Modeling inducible neuropathologies of the retina with differential phenotypes in organoids

por Völkner, Manuela, Wagner, Felix, Kurth, Thomas, Sykes, Alex M., Del Toro Runzer, Claudia, Ebner, Lynn J. A., Kavak, Cagri, Alexaki, Vasileia Ismini, Cimalla, Peter, Mehner, Mirko, Koch, Edmund, Karl, Mike O.
Publicado 2023

Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation

por Todorova, Vyara, Stauffacher, Mia Fee, Ravotto, Luca, Nötzli, Sarah, Karademir, Duygu, Ebner, Lynn J. A., Imsand, Cornelia, Merolla, Luca, Hauck, Stefanie M., Samardzija, Marijana, Saab, Aiman S., Barros, L. Felipe, Weber, Bruno, Grimm, Christian
Publicado 2023

HBEGF-TNF induce a complex outer retinal pathology with photoreceptor cell extrusion in human organoids

por Völkner, Manuela, Wagner, Felix, Steinheuer, Lisa Maria, Carido, Madalena, Kurth, Thomas, Yazbeck, Ali, Schor, Jana, Wieneke, Stephanie, Ebner, Lynn J. A., Del Toro Runzer, Claudia, Taborsky, David, Zoschke, Katja, Vogt, Marlen, Canzler, Sebastian, Hermann, Andreas, Khattak, Shahryar, Hackermüller, Jörg, Karl, Mike O.
Publicado 2022