Identification of personal risk of breast cancer: genetics

por Eccles, Diana M
Publicado 2008

Methylenetetrahydrofolate reductase polymorphism and susceptibility to breast cancer

por Campbell, Ian G, Baxter, Simon W, Eccles, Diana M, Choong, David YH
Publicado 2002

The DNMT3B C→T promoter polymorphism and risk of breast cancer in a British population: a case-control study

por Montgomery, Karen G, Liu, Mira CP, Eccles, Diana M, Campbell, Ian G
Publicado 2004

A novel duplication polymorphism in the FANCA promoter and its association with breast and ovarian cancer

por Thompson, Ella, Dragovic, Rebecca L, Stephenson, Sally-Anne, Eccles, Diana M, Campbell, Ian G, Dobrovic, Alexander
Publicado 2005

Local Recurrence and Breast Oncological Surgery in Young Women With Breast Cancer: The POSH Observational Cohort Study

por Maishman, Tom, Cutress, Ramsey I., Hernandez, Aurea, Gerty, Sue, Copson, Ellen. R., Durcan, Lorraine, Eccles, Diana M.
Publicado 2017

Influence of the MDM2 single nucleotide polymorphism SNP309 on tumour development in BRCA1 mutation carriers

por Copson, Ellen R, White, Helen E, Blaydes, Jeremy P, Robinson, David O, Johnson, Peter W, Eccles, Diana M
Publicado 2006

Patient decision support resources inform decisions about cancer susceptibility genetic testing and risk management: a systematic review of patient impact and experience

por Kohut, Kelly, Morton, Kate, Turner, Lesley, Shepherd, Jonathan, Fenerty, Vicky, Woods, Lois, Grimmett, Chloe, Eccles, Diana M., Foster, Claire
Publicado 2023

Person-based co-design of a decision aid template for people with a genetic predisposition to cancer

por Morton, Kate, Kohut, Kelly, Turner, Lesley, Smith, Sian, Crosbie, Emma J., Ryan, Neil, Grimmett, Chloe, Eccles, Diana M., Foster, Claire
Publicado 2022

Analysis of RAD51D in Ovarian Cancer Patients and Families with a History of Ovarian or Breast Cancer

por Thompson, Ella R., Rowley, Simone M., Sawyer, Sarah, kConFab, Eccles, Diana M., Trainer, Alison H., Mitchell, Gillian, James, Paul A., Campbell, Ian G.
Publicado 2013

The Angelina Jolie effect: how high celebrity profile can have a major impact on provision of cancer related services

por Evans, D Gareth R, Barwell, Julian, Eccles, Diana M, Collins, Amanda, Izatt, Louise, Jacobs, Chris, Donaldson, Alan, Brady, Angela F, Cuthbert, Andrew, Harrison, Rachel, Thomas, Sue, Howell, Anthony, Miedzybrodzka, Zosia, Murray, Alex
Publicado 2014

Combining evidence for and against pathogenicity for variants in cancer susceptibility genes: CanVIG-UK consensus recommendations

por Garrett, Alice, Durkie, Miranda, Callaway, Alison, Burghel, George J, Robinson, Rachel, Drummond, James, Torr, Bethany, Cubuk, Cankut, Berry, Ian R, Wallace, Andrew J, Ellard, Sian, Eccles, Diana M, Tischkowitz, Marc, Hanson, Helen, Turnbull, Clare
Publicado 2021

Breast cancer in patients with germline TP53 pathogenic variants have typical tumour characteristics: the Cohort study of TP53 carrier early onset breast cancer (COPE study)

por Packwood, Kate, Martland, Guy, Sommerlad, Matthew, Shaw, Emily, Moutasim, Karwan, Thomas, Gareth, Bateman, Adrian C, Jones, Louise, Haywood, Linda, Evans, D Gareth, Birch, Jillian M, Alsalmi, Ohud A, Henderson, Alex, Poplawski, Nicola, Eccles, Diana M
Publicado 2019

Multifocal breast cancers are more prevalent in BRCA2 versus BRCA1 mutation carriers

por McCrorie, Alan D, Ashfield, Susannah, Begley, Aislinn, Mcilmunn, Colin, Morrison, Patrick J, Boyd, Clinton, Eccles, Bryony, Greville‐Heygate, Stephanie, Copson, Ellen R, Cutress, Ramsey I, Eccles, Diana M, Savage, Kienan I, McIntosh, Stuart A
Publicado 2020

Quantifying the cumulative effect of low-penetrance genetic variants on breast cancer risk

por Smyth, Conor, Špakulová, Iva, Cotton-Barratt, Owen, Rafiq, Sajjad, Tapper, William, Upstill-Goddard, Rosanna, Hopper, John L, Makalic, Enes, Schmidt, Daniel F, Kapuscinski, Miroslav, Fliege, Jörg, Collins, Andrew, Brodzki, Jacek, Eccles, Diana M, MacArthur, Ben D
Publicado 2015

A Dominantly Inherited 5′ UTR Variant Causing Methylation-Associated Silencing of BRCA1 as a Cause of Breast and Ovarian Cancer

por Evans, D.Gareth R., van Veen, Elke M., Byers, Helen J., Wallace, Andrew J., Ellingford, Jamie M., Beaman, Glenda, Santoyo-Lopez, Javier, Aitman, Timothy J., Eccles, Diana M., Lalloo, Fiona I., Smith, Miriam J., Newman, William G.
Publicado 2018

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation

por Candido dos Reis, Francisco J., Wishart, Gordon C., Dicks, Ed M., Greenberg, David, Rashbass, Jem, Schmidt, Marjanka K., van den Broek, Alexandra J., Ellis, Ian O., Green, Andrew, Rakha, Emad, Maishman, Tom, Eccles, Diana M., Pharoah, Paul D. P.
Publicado 2017

Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants

por Loong, Lucy, Cubuk, Cankut, Choi, Subin, Allen, Sophie, Torr, Beth, Garrett, Alice, Loveday, Chey, Durkie, Miranda, Callaway, Alison, Burghel, George J., Drummond, James, Robinson, Rachel, Berry, Ian R., Wallace, Andrew, Eccles, Diana M., Tischkowitz, Marc, Ellard, Sian, Ware, James S., Hanson, Helen, Turnbull, Clare
Publicado 2022

UK recommendations for SDHA germline genetic testing and surveillance in clinical practice

por Hanson, Helen, Durkie, Miranda, Lalloo, Fiona, Izatt, Louise, McVeigh, Terri P, Cook, Jackie A, Brewer, Carole, Drummond, James, Butler, Samantha, Cranston, Treena, Casey, Ruth, Tan, Tricia, Morganstein, Daniel, Eccles, Diana M, Tischkowitz, Marc, Turnbull, Clare, Woodward, Emma Roisin, Maher, Eamonn R
Publicado 2023

Clinical testing of BRCA1 and BRCA2: a worldwide snapshot of technological practices

por Toland, Amanda Ewart, Forman, Andrea, Couch, Fergus J., Culver, Julie O., Eccles, Diana M., Foulkes, William D., Hogervorst, Frans B. L., Houdayer, Claude, Levy-Lahad, Ephrat, Monteiro, Alvaro N., Neuhausen, Susan L., Plon, Sharon E., Sharan, Shyam K., Spurdle, Amanda B., Szabo, Csilla, Brody, Lawrence C.
Publicado 2018

Evidence of Stage Shift in Women Diagnosed With Ovarian Cancer During Phase II of the United Kingdom Familial Ovarian Cancer Screening Study

por Rosenthal, Adam N., Fraser, Lindsay S.M., Philpott, Susan, Manchanda, Ranjit, Burnell, Matthew, Badman, Philip, Hadwin, Richard, Rizzuto, Ivana, Benjamin, Elizabeth, Singh, Naveena, Evans, D. Gareth, Eccles, Diana M., Ryan, Andy, Liston, Robert, Dawnay, Anne, Ford, Jeremy, Gunu, Richard, Mackay, James, Skates, Steven J., Menon, Usha, Jacobs, Ian J.
Publicado 2017