Targeting aurora kinases limits tumour growth through DNA damage-mediated senescence and blockade of NF-κB impairs this drug-induced senescence

por Liu, Yan, Hawkins, Oriana E, Su, Yingjun, Vilgelm, Anna E, Sobolik, Tammy, Thu, Yee-Mon, Kantrow, Sara, Splittgerber, Ryan C, Short, Sarah, Amiri, Katayoun I, Ecsedy, Jeffery A, Sosman, Jeffery A, Kelley, Mark C, Richmond, Ann
Publicado 2013

Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer

por Pitts, Todd M., Bradshaw, Erica L., Bagby, Stacey M., Hyatt, Stephanie L., Selby, Heather M., Spreafico, Anna, Tentler, John J., McPhillips, Kelly, Klauck, Peter J., Capasso, Anna, Diamond, Jennifer R., Davis, S. Lindsey, Tan, Aik Choon, Arcaroli, John J., Purkey, Alicia, Messersmith, Wells A., Ecsedy, Jeffery A., Eckhardt, S. Gail
Publicado 2016