Preclinical Studies of a Novel Human PD-1 B-Cell Peptide Cancer Vaccine PD1-Vaxx From BALB/c Mice to Beagle Dogs and to Non-Human Primates (Cynomolgus Monkeys)

por Guo, Linlin, Overholser, Jay, Good, Anthony J., Ede, Nicholas J., Kaumaya, Pravin T. P.
Publicado 2022

A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synerg...

por Guo, Linlin, Overholser, Jay, Darby, Heather, Ede, Nicholas J., Kaumaya, Pravin T.P
Publicado 2022

Enhanced and long term immunogenicity of a Her-2/neu multi-epitope vaccine conjugated to the carrier CRM197 in conjunction with the adjuvant Montanide

por Tobias, Joshua, Jasinska, Joanna, Baier, Karin, Kundi, Michael, Ede, Nicholas, Zielinski, Christoph, Wiedermann, Ursula
Publicado 2017

Development of the B cell cancer vaccine HER-vaxx for the treatment of her-2 expressing cancers

por Ede, Nicholas J., Good, Anthony J., Tobias, Joshua, Garner-Spitzer, Erika, Zielinski, Christoph C., Wiedermann, Ursula
Publicado 2022

An Oncolytic Poxvirus Encoding hNIS, Shows Antitumor Efficacy and Allows Tumor Imaging in a Liver Cancer Model

por Chaurasiya, Shyambabu, Valencia, Hannah, Zhang, Zhifang, Kim, Sang-In, Yang, Annie, Lu, Jianming, Woo, Yanghee, Warner, Susanne G., Ede, Nicholas J., Fong, Yuman
Publicado 2023

A comprehensive preclinical study supporting clinical trial of oncolytic chimeric poxvirus CF33-hNIS-anti-PD-L1 to treat breast cancer

por Chaurasiya, Shyambabu, Yang, Annie, Zhang, Zhifang, Lu, Jianming, Valencia, Hannah, Kim, Sang-In, Woo, Yanghee, Warner, Suanne G., Olafsen, Tove, Zhao, Yuqi, Wu, Xiwei, Fein, Seymour, Cheng, Linda, Cheng, Maria, Ede, Nicholas, Fong, Yuman
Publicado 2021

CF33-hNIS-anti-PD-L1 oncolytic virus followed by trastuzumab-deruxtecan in a patient with metastatic triple negative breast cancer: a case study

por Yuan, Yuan, Egelston, Colt, Colunga Flores, Oscar, Chaurasiya, Shyambabu, Lin, David, Chang, Helen, Chong, Leslie Mi Ok, Seiz, Amanda, Shah, Monil, Meisen, W. Hans, Tang, Aileen, Martinez, Norma, Pickett, Wichanee, Murga, Mireya, Yost, Susan E., Stewart, Daphne, Zhang, Jianying, Ede, Nicholas, Modi, Badri, Kessler, Jonathan, Rand, Jamie, Fong, Yuman
Publicado 2023