Q&A: What are exosomes, exactly?

por Edgar, James R.
Publicado 2016

Spastin MIT Domain Disease-Associated Mutations Disrupt Lysosomal Function

por Allison, Rachel, Edgar, James R., Reid, Evan
Publicado 2019

Hrs- and CD63-Dependent Competing Mechanisms Make Different Sized Endosomal Intraluminal Vesicles

por Edgar, James R, Eden, Emily R, Futter, Clare E
Publicado 2014

ESCRTs regulate amyloid precursor protein sorting in multivesicular bodies and intracellular amyloid-β accumulation

por Edgar, James R., Willén, Katarina, Gouras, Gunnar K., Futter, Clare E.
Publicado 2015

Tetherin is an exosomal tether

por Edgar, James R, Manna, Paul T, Nishimura, Shinichi, Banting, George, Robinson, Margaret S
Publicado 2016

The WDR11 complex facilitates the tethering of AP-1-derived vesicles

por Navarro Negredo, Paloma, Edgar, James R., Manna, Paul T., Antrobus, Robin, Robinson, Margaret S.
Publicado 2018

Exploiting Connections for Viral Replication

por Wong, Louise H., Edgar, James R., Martello, Andrea, Ferguson, Brian J., Eden, Emily R.
Publicado 2021

Aβ accumulation causes MVB enlargement and is modelled by dominant negative VPS4A

por Willén, Katarina, Edgar, James R., Hasegawa, Takafumi, Tanaka, Nobuyuki, Futter, Clare E., Gouras, Gunnar K.
Publicado 2017

Fas Ligand localizes to intraluminal vesicles within NK cell cytolytic granules and is enriched at the immune synapse

por Lee, Jeansun, Dieckmann, Nele M.G., Edgar, James R., Griffiths, Gillian M., Siegel, Richard M.
Publicado 2018

Fractionation profiling: a fast and versatile approach for mapping vesicle proteomes and protein–protein interactions

por Borner, Georg H. H., Hein, Marco Y., Hirst, Jennifer, Edgar, James R., Mann, Matthias, Robinson, Margaret S.
Publicado 2014

Molecular Mechanisms of Disease Pathogenesis Differ in Krabbe Disease Variants

por Spratley, Samantha J., Hill, Chris H., Viuff, Agnete H., Edgar, James R., Skjødt, Karsten, Deane, Janet E.
Publicado 2016

Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking

por Hirst, Jennifer, Edgar, James R., Borner, Georg H. H., Li, Sam, Sahlender, Daniela A., Antrobus, Robin, Robinson, Margaret S.
Publicado 2015

Contribution of the clathrin adaptor AP-1 subunit µ1 to acidic cluster protein sorting

por Navarro Negredo, Paloma, Edgar, James R., Wrobel, Antoni G., Zaccai, Nathan R., Antrobus, Robin, Owen, David J., Robinson, Margaret S.
Publicado 2017

A dysfunctional endolysosomal pathway common to two sub-types of demyelinating Charcot–Marie–Tooth disease

por Edgar, James R., Ho, Anita K., Laurá, Matilde, Horvath, Rita, Reilly, Mary M., Luzio, J. Paul, Roberts, Rhys C.
Publicado 2020

Role of clathrin in dense core vesicle biogenesis

por Sahu, Bhavani S., Manna, Paul T., Edgar, James R., Antrobus, Robin, Mahata, Sushil K., Bartolomucci, Alessandro, Borner, Georg H. H., Robinson, Margaret S.
Publicado 2017

OPTN recruitment to a Golgi-proximal compartment regulates immune signalling and cytokine secretion

por O'Loughlin, Thomas, Kruppa, Antonina J., Ribeiro, Andre L. R., Edgar, James R., Ghannam, Abdulaziz, Smith, Andrew M., Buss, Folma
Publicado 2020

AP-4 vesicles contribute to spatial control of autophagy via RUSC-dependent peripheral delivery of ATG9A

por Davies, Alexandra K., Itzhak, Daniel N., Edgar, James R., Archuleta, Tara L., Hirst, Jennifer, Jackson, Lauren P., Robinson, Margaret S., Borner, Georg H. H.
Publicado 2018

Organelle tethering, pore formation and SNARE compensation in the late endocytic pathway

por Davis, Luther J., Bright, Nicholas A., Edgar, James R., Parkinson, Michael D. J., Wartosch, Lena, Mantell, Judith, Peden, Andrew A., Luzio, J. Paul
Publicado 2021

Frontotemporal dementia causative CHMP2B impairs neuronal endolysosomal traffic-rescue by TMEM106B knockdown

por Clayton, Emma L, Milioto, Carmelo, Muralidharan, Bhavana, Norona, Frances E, Edgar, James R, Soriano, Armand, Jafar-nejad, Paymaan, Rigo, Frank, Collinge, John, Isaacs, Adrian M
Publicado 2018

Ultrastructural insight into SARS-CoV-2 entry and budding in human airway epithelium

por Pinto, Andreia L., Rai, Ranjit K., Brown, Jonathan C., Griffin, Paul, Edgar, James R., Shah, Anand, Singanayagam, Aran, Hogg, Claire, Barclay, Wendy S., Futter, Clare E., Burgoyne, Thomas
Publicado 2022