Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development

por Edgar, John M., Michaels, Yale S., Zandstra, Peter W.
Publicado 2022

DLL4 and VCAM1 enhance the emergence of T cell–competent hematopoietic progenitors from human pluripotent stem cells

por Michaels, Yale S., Edgar, John M., Major, Matthew C., Castle, Elizabeth L., Zimmerman, Carla, Yin, Ting, Hagner, Andrew, Lau, Charles, Hsu, Han Hsuan, Ibañez-Rios, M. Iliana, Durland, Lauren J., Knapp, David J. H. F., Zandstra, Peter W.
Publicado 2022

Sex biased human thymic architecture guides T cell development through spatially defined niches

por Stankiewicz, Laura N, Salim, Kevin, Flaschner, Emily A, Wang, Yu Xin, Edgar, John M, Lin, Bruce ZB, Bingham, Grace C, Major, Matthew C, Jones, Ross D, Blau, Helen M, Rideout, Elizabeth J, Levings, Megan K, Zandstra, Peter W, Rossi, Fabio MV
Publicado 2023