Chemical Tools to Image the Activity of PAR-Cleaving Proteases

por Lee, Irene Y., Tantisirivat, Piyapa, Edgington-Mitchell, Laura E.
Publicado 2023

System-wide biochemical analysis reveals ozonide antimalarials initially act by disrupting Plasmodium falciparum haemoglobin digestion

por Giannangelo, Carlo, Siddiqui, Ghizal, De Paoli, Amanda, Anderson, Bethany M., Edgington-Mitchell, Laura E., Charman, Susan A., Creek, Darren J.
Publicado 2020

Novel broad-spectrum activity-based probes to profile malarial cysteine proteases

por Tan, Michele S. Y., Davison, Dara, Sanchez, Mateo I., Anderson, Bethany M., Howell, Stephen, Snijders, Ambrosius, Edgington-Mitchell, Laura E., Deu, Edgar
Publicado 2020

Correction: Novel broad-spectrum activity-based probes to profile malarial cysteine proteases

por Tan, Michele S. Y., Davison, Dara, Sanchez, Mateo I., Anderson, Bethany M., Howell, Stephen, Snijders, Ambrosius P., Edgington-Mitchell, Laura E., Deu, Edgar
Publicado 2020

Cysteine cathepsin activity suppresses osteoclastogenesis of myeloid-derived suppressor cells in breast cancer

por Edgington-Mitchell, Laura E., Rautela, Jai, Duivenvoorden, Hendrika M., Jayatilleke, Krishnath M., van der Linden, Wouter A., Verdoes, Martijn, Bogyo, Matthew, Parker, Belinda S.
Publicado 2015

Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain–associated conditions

por Roitman, Maria, Edgington-Mitchell, Laura E., Mangum, Jon, Ziogas, James, Adamides, Alexios A., Myles, Paul, Choo-Bunnett, Hearan, Bunnett, Nigel W., Gunnersen, Jenny M.
Publicado 2019

Loss of O-Linked Protein Glycosylation in Burkholderia cenocepacia Impairs Biofilm Formation and Siderophore Activity and Alters Transcriptional Regulators

por Oppy, Cameron C., Jebeli, Leila, Kuba, Miku, Oates, Clare V., Strugnell, Richard, Edgington-Mitchell, Laura E., Valvano, Miguel A., Hartland, Elizabeth L., Newton, Hayley J., Scott, Nichollas E.
Publicado 2019

Lysosomal degradation products induce Coxiella burnetii virulence

por Newton, Patrice, Thomas, David R., Reed, Shawna C. O., Lau, Nicole, Xu, Bangyan, Ong, Sze Ying, Pasricha, Shivani, Madhamshettiwar, Piyush B., Edgington-Mitchell, Laura E., Simpson, Kaylene J., Roy, Craig R., Newton, Hayley J.
Publicado 2020

High-Resolution Confocal Fluorescence Imaging of Serine Hydrolase Activity in Cryosections – Application to Glioma Brain Unveils Activity Hotspots Originating from Tumor-Associated...

por Aaltonen, Niina, Singha, Prosanta K., Jakupović, Hermina, Wirth, Thomas, Samaranayake, Haritha, Pasonen-Seppänen, Sanna, Rilla, Kirsi, Varjosalo, Markku, Edgington-Mitchell, Laura E., Kasperkiewicz, Paulina, Drag, Marcin, Kälvälä, Sara, Moisio, Eemeli, Savinainen, Juha R., Laitinen, Jarmo T.
Publicado 2020

Application of a chemical probe to detect neutrophil elastase activation during inflammatory bowel disease

por Anderson, Bethany M., Poole, Daniel P., Aurelio, Luigi, Ng, Garrett Z., Fleischmann, Markus, Kasperkiewicz, Paulina, Morissette, Celine, Drag, Marcin, van Driel, Ian R., Schmidt, Brian L., Vanner, Stephen J., Bunnett, Nigel W., Edgington-Mitchell, Laura E.
Publicado 2019

Cathepsin S Evokes PAR(2)-Dependent Pain in Oral Squamous Cell Carcinoma Patients and Preclinical Mouse Models

por Tu, Nguyen Huu, Inoue, Kenji, Chen, Elyssa, Anderson, Bethany M., Sawicki, Caroline M., Scheff, Nicole N., Tran, Hung D., Kim, Dong H., Alemu, Robel G., Yang, Lei, Dolan, John C., Liu, Cheng Z., Janal, Malvin N., Latorre, Rocco, Jensen, Dane D., Bunnett, Nigel W., Edgington-Mitchell, Laura E., Schmidt, Brian L.
Publicado 2021

Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86

por Liu, Haiyin, Wilson, Kayla R., Firth, Ashley M., Macri, Christophe, Schriek, Patrick, Blum, Annabelle B., Villar, Javiera, Wormald, Samuel, Shambrook, Mitch, Xu, Bangyan, Lim, Hui Jing, McWilliam, Hamish E. G., Hill, Andrew F., Edgington-Mitchell, Laura E., Caminschi, Irina, Lahoud, Mireille H., Segura, Elodie, Herold, Marco J., Villadangos, Jose A., Mintern, Justine D.
Publicado 2022