An Evaluation of Different Target Enrichment Methods in Pooled Sequencing Designs for Complex Disease Association Studies

por Day-Williams, Aaron G., McLay, Kirsten, Drury, Eleanor, Edkins, Sarah, Coffey, Alison J., Palotie, Aarno, Zeggini, Eleftheria
Publicado 2011

Gene filtering strategies for machine learning guided biomarker discovery using neonatal sepsis RNA-seq data

por Parkinson, Edward, Liberatore , Federico, Watkins , W. John, Andrews , Robert, Edkins , Sarah, Hibbert , Julie, Strunk , Tobias, Currie , Andrew, Ghazal , Peter
Publicado 2023

PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data

por Greenman, Chris D., Bignell, Graham, Butler, Adam, Edkins, Sarah, Hinton, Jon, Beare, Dave, Swamy, Sajani, Santarius, Thomas, Chen, Lina, Widaa, Sara, Futreal, P. Andy, Stratton, Michael R.
Publicado 2010

Distinctive Features of Orbital Adipose Tissue (OAT) in Graves’ Orbitopathy

por Zhang, Lei, Evans, Anna, von Ruhland, Chris, Draman, Mohd Shazli, Edkins, Sarah, Vincent, Amy E., Berlinguer-Palmini, Rolando, Rees, D. Aled, Haridas, Anjana S, Morris, Dan, Tee, Andrew R., Ludgate, Marian, Turnbull, Doug M., Karpe, Fredrik, Dayan, Colin M.
Publicado 2020

Gata2 as a Crucial Regulator of Stem Cells in Adult Hematopoiesis and Acute Myeloid Leukemia

por Menendez-Gonzalez, Juan Bautista, Vukovic, Milica, Abdelfattah, Ali, Saleh, Lubaid, Almotiri, Alhomidi, Thomas, Leigh-anne, Agirre-Lizaso, Aloña, Azevedo, Aleksandra, Menezes, Ana Catarina, Tornillo, Giusy, Edkins, Sarah, Kong, Kay, Giles, Peter, Anjos-Afonso, Fernando, Tonks, Alex, Boyd, Ashleigh S., Kranc, Kamil R., Rodrigues, Neil P.
Publicado 2019

Zeb1 modulates hematopoietic stem cell fates required for suppressing acute myeloid leukemia

por Almotiri, Alhomidi, Alzahrani, Hamed, Menendez-Gonzalez, Juan Bautista, Abdelfattah, Ali, Alotaibi, Badi, Saleh, Lubaid, Greene, Adelle, Georgiou, Mia, Gibbs, Alex, Alsayari, Amani, Taha, Sarab, Thomas, Leigh-anne, Shah, Dhruv, Edkins, Sarah, Giles, Peter, Stemmler, Marc P., Brabletz, Simone, Brabletz, Thomas, Boyd, Ashleigh S., Siebzehnrubl, Florian A., Rodrigues, Neil P.
Publicado 2021

mSep: investigating physiological and immune-metabolic biomarkers in septic and healthy pregnant women to predict feto-maternal immune health – a prospective observational cohort s...

por Sharma, Simran, Zaher, Summia, Rodrigues, Patrícia R S, Davies, Luke C, Edkins, Sarah, Strang, Angela, Chakraborty, Mallinath, Watkins, W John, Andrews, Robert, Parkinson, Edward, Angelopoulos, Nicos, Moet, Linda, Shepherd, Freya, Davies, Kate Megan Megan, White, Daniel, Oram, Shaun, Siddall, Kate, Keeping, Vikki, Simpson, Kathryn, Faggian, Federica, Bray, Maryanne, Bertorelli, Claire, Bell, Sarah, Collis, Rachel E, McLaren, James E, Labeta, Mario, O’Donnell, Valerie B, Ghazal, Peter
Publicado 2022

Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

por Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N., Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G., Small, Kerrin S., Teo, Yik Ying, Kwiatkowski, Dominic P., Rockett, Kirk A., Barrett, Jeffrey C., Spencer, Chris C. A.
Publicado 2013

Correction: Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

por Band, Gavin, Le, Quang Si, Jostins, Luke, Pirinen, Matti, Kivinen, Katja, Jallow, Muminatou, Sisay-Joof, Fatoumatta, Bojang, Kalifa, Pinder, Margaret, Sirugo, Giorgio, Conway, David J., Nyirongo, Vysaul, Kachala, David, Molyneux, Malcolm, Taylor, Terrie, Ndila, Carolyne, Peshu, Norbert, Marsh, Kevin, Williams, Thomas N., Alcock, Daniel, Andrews, Robert, Edkins, Sarah, Gray, Emma, Hubbart, Christina, Jeffreys, Anna, Rowlands, Kate, Schuldt, Kathrin, Clark, Taane G., Small, Kerrin S., Teo, Yik Ying, Kwiatkowski, Dominic P., Rockett, Kirk A., Barrett, Jeffrey C., Spencer, Chris C. A.
Publicado 2013

nSeP: immune and metabolic biomarkers for early detection of neonatal sepsis—protocol for a prospective multicohort study

por Chakraborty, Mallinath, Rodrigues, Patrícia R S, Watkins, W John, Hayward, Angela, Sharma, Alok, Hayward, Rachel, Smit, Elisa, Jones, Rebekka, Goel, Nitin, Asokkumar, Amar, Calvert, Jennifer, Odd, David, Morris, Ian, Doherty, Cora, Elliott, Sian, Strang, Angela, Andrews, Robert, Zaher, Summia, Sharma, Simran, Bell, Sarah, Oruganti, Siva, Smith, Claire, Orme, Judith, Edkins, Sarah, Craigon, Marie, White, Daniel, Dantoft, Widad, Davies, Luke C, Moet, Linda, McLaren, James E, Clarkstone, Samantha, Watson, Gareth L, Hood, Kerenza, Kotecha, Sailesh, Morgan, B. Paul, O’Donnell, Valerie B, Ghazal, Peter
Publicado 2021

Immune and metabolic markers for identifying and investigating severe Coronavirus disease and Sepsis in children and young people (pSeP/COVID ChYP study): protocol for a prospectiv...

por Oruganti, Sivakumar, Rodrigues, Patrícia R S, White, Daniel, Watkins, William John, Shapey, Selyf, Barrow, Anna, al Samsam, Rim, Ali, Sara, Gajraj, Malcolm, Skone, Richard, Jardine, Michelle, Evans, Jennifer, Struik, Siske, Song, Jong Eun, Abood, Lloyd, Paquete, Barbara, Foulkes, Sian, Saunders, Benjamin, Strang, Angela, Kotecha, Sarah Joanne, Phillips, Bethan, Evans, Awen, Buchanan, Iona, Bowes, Susan, Ali, Begum, Gore, Maya, Thomas-Turner, Rhian, Andrews, Robert, Zaher, Summia, Sharma, Simran, Chakraborty, Mallinath, Parkinson, Edward, Liberatore, Federico, Woolley, Thomas, Edkins, Sarah, Davies, Luke C, Moet, Linda, McLaren, James E, Watson, Gareth L, O'Donnell, Valerie, Hood, Kerry, Ghazal, Peter
Publicado 2023

COMPLEX LANDSCAPES OF SOMATIC REARRANGEMENT IN HUMAN BREAST CANCER GENOMES

por Stephens, Philip J, McBride, David J, Lin, Meng-Lay, Varela, Ignacio, Pleasance, Erin D, Simpson, Jared T, Stebbings, Lucy A, Leroy, Catherine, Edkins, Sarah, Mudie, Laura J, Greenman, Chris D, Jia, Mingming, Latimer, Calli, Teague, Jon W, Lau, King Wai, Burton, John, Quail, Michael A, Swerdlow, Harold, Churcher, Carol, Natrajan, Rachael, Sieuwerts, Anieta M, Martens, John WM, Silver, Daniel P, Langerod, Anita, Russnes, Hege EG, Foekens, John A, Reis-Filho, Jorge S, van ’t Veer, Laura, Richardson, Andrea L, Børreson-Dale, Anne-Lise, Campbell, Peter J, Futreal, P Andrew, Stratton, Michael R
Publicado 2009

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

por Hinks, Anne, Cobb, Joanna, Marion, Miranda C., Prahalad, Sampath, Sudman, Marc, Bowes, John, Martin, Paul, Comeau, Mary E., Sajuthi, Satria, Andrews, Robert, Brown, Milton, Chen, Wei-Min, Concannon, Patrick, Deloukas, Panos, Edkins, Sarah, Eyre, Stephen, Gaffney, Patrick M., Guthery, Stephen L., Guthridge, Joel M., Hunt, Sarah E., James, Judith A., Keddache, Mehdi, Moser, Kathy L., Nigrovic, Peter A., Onengut-Gumuscu, Suna, Onslow, Mitchell L., Rosé, Carlos D., Rich, Stephen S., Steel, Kathryn J.A., Wakeland, Edward K., Wallace, Carol A., Wedderburn, Lucy R., Woo, Patricia, Bohnsack, John F., Haas, Johannes Peter, Glass, David N., Langefeld, Carl D., Thomson, Wendy, Thompson, Susan D.
Publicado 2013

A small cell lung cancer genome reports complex tobacco exposure signatures

por Pleasance, Erin D, Stephens, Philip J, O'Meara, Sarah, McBride, David J, Meynert, Alison, Jones, David, Lin, Meng-Lay, Beare, David, Lau, King Wai, Greenman, Chris, Varela, Ignacio, Nik-Zainal, Serena, Davies, Helen R, Ordoñez, Gonzalo R, Mudie, Laura J, Latimer, Calli, Edkins, Sarah, Stebbings, Lucy, Chen, Lina, Jia, Mingming, Leroy, Catherine, Marshall, John, Menzies, Andrew, Butler, Adam, Teague, Jon W, Mangion, Jonathon, Sun, Yongming A, McLaughlin, Stephen F, Peckham, Heather E, Tsung, Eric F, Costa, Gina L, Lee, Clarence C, Minna, John D, Gazdar, Adi, Birney, Ewan, Rhodes, Michael D, McKernan, Kevin J, Stratton, Michael R, Futreal, P Andrew, Campbell, Peter J
Publicado 2009

High density genetic mapping identifies new susceptibility loci for rheumatoid arthritis

por Eyre, Steve, Bowes, John, Diogo, Dorothée, Lee, Annette, Barton, Anne, Martin, Paul, Zhernakova, Alexandra, Stahl, Eli, Viatte, Sebastien, McAllister, Kate, Amos, Christopher I., Padyukov, Leonid, Toes, Rene E.M., Huizinga, Tom W.J., Wijmenga, Cisca, Trynka, Gosia, Franke, Lude, Westra, Harm-Jan, Alfredsson, Lars, Hu, Xinli, Sandor, Cynthia, de Bakker, Paul I.W., Davila, Sonia, Khor, Chiea Chuen, Heng, Khai Koon, Andrews, Robert, Edkins, Sarah, Hunt, Sarah E, Langford, Cordelia, Symmons, Deborah, Concannon, Pat, Onengut-Gumuscu, Suna, Rich, Stephen S, Deloukas, Panos, Gonzalez-Gay, Miguel A., Rodriguez-Rodriguez, Luis, Ärlsetig, Lisbeth, Martin, Javier, Rantapää-Dahlqvist, Solbritt, Plenge, Robert, Raychaudhuri, Soumya, Klareskog, Lars, Gregersen, Peter K, Worthington, Jane
Publicado 2012

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

por Dalgliesh, Gillian L., Furge, Kyle, Greenman, Chris, Chen, Lina, Bignell, Graham, Butler, Adam, Davies, Helen, Edkins, Sarah, Hardy, Claire, Latimer, Calli, Teague, Jon, Andrews, Jenny, Barthorpe, Syd, Beare, Dave, Buck, Gemma, Campbell, Peter J., Forbes, Simon, Jia, Mingming, Jones, David, Knott, Henry, Kok, Chai Yin, Lau, King Wai, Leroy, Catherine, Lin, Meng-Lay, McBride, David J, Maddison, Mark, Maguire, Simon, McLay, Kirsten, Menzies, Andrew, Mironenko, Tatiana, Mulderrig, Lee, Mudie, Laura, O’Meara, Sarah, Pleasance, Erin, Rajasingham, Arjunan, Shepherd, Rebecca, Smith, Raffaella, Stebbings, Lucy, Stephens, Philip, Tang, Gurpreet, Tarpey, Patrick S, Turrell, Kelly, Dykema, Karl J., Khoo, Sok Kean, Petillo, David, Wondergem, Bill, Anema, John, Kahnoski, Richard J., Teh, Bin Tean, Stratton, Michael R., Futreal, P. Andrew
Publicado 2010

Dissection of the genetics of Parkinson's disease identifies an additional association 5′ of SNCA and multiple associated haplotypes at 17q21

por Spencer, Chris C.A., Plagnol, Vincent, Strange, Amy, Gardner, Michelle, Paisan-Ruiz, Coro, Band, Gavin, Barker, Roger A., Bellenguez, Celine, Bhatia, Kailash, Blackburn, Hannah, Blackwell, Jennie M., Bramon, Elvira, Brown, Martin A., Brown, Matthew A., Burn, David, Casas, Juan-Pablo, Chinnery, Patrick F., Clarke, Carl E., Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Edkins, Sarah, Evans, Jonathan, Freeman, Colin, Gray, Emma, Hardy, John, Hudson, Gavin, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Lees, Andrew J., Markus, Hugh S., Mathew, Christopher G., McCarthy, Mark I., Morrison, Karen E., Palmer, Colin N.A., Pearson, Justin P., Peltonen, Leena, Pirinen, Matti, Plomin, Robert, Potter, Simon, Rautanen, Anna, Sawcer, Stephen J., Su, Zhan, Trembath, Richard C., Viswanathan, Ananth C., Williams, Nigel W., Morris, Huw R., Donnelly, Peter, Wood, Nicholas W.
Publicado 2011

Common variants near ATM are associated with glycemic response to metformin in type 2 diabetes

por Zhou, Kaixin, Bellenguez, Celine, Spencer, Chris CA, Bennett, Amanda J, Coleman, Ruth L, Tavendale, Roger, Hawley, Simon A., Donnelly, Louise A, Schofield, Chris, Groves, Christopher J, Burch, Lindsay, Carr, Fiona, Strange, Amy, Freeman, Colin, Blackwell, Jenefer M, Bramon, Elvira, Brown, Matthew A, Casas, Juan P, Corvin, Aiden, Craddock, Nicholas, Deloukas, Panos, Dronov, Serge, Duncanson, Audrey, Edkins, Sarah, Gray, Emma, Hunt, Sarah, Jankowski, Janusz, Langford, Cordelia, Markus, Hugh S, Mathew, Christopher G, Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J, Samani, Nilesh J, Trembath, Richard, Viswanathan, Ananth C, Wood, Nicholas W, Harries, Lorna W, Hattersley, Andrew T, Doney, Alex SF, Colhoun, Helen, Morris, Andrew D, Sutherland, Calum, Hardie, D. Grahame, Peltonen, Leena, McCarthy, Mark I, Holman, Rury R., Palmer, Colin N.A., Donnelly, Peter, Pearson, Ewan R
Publicado 2010

Common variants in the HLA-DRB1-HLA-DQA1 Class II region are associated with susceptibility to visceral leishmaniasis

por Fakiola, Michaela, Strange, Amy, Cordell, Heather J., Miller, E. Nancy, Pirinen, Matti, Su, Zhan, Mishra, Anshuman, Mehrotra, Sanjana, Monteiro, Gloria R., Band, Gavin, Bellenguez, Céline, Dronov, Serge, Edkins, Sarah, Freeman, Colin, Giannoulatou, Eleni, Gray, Emma, Hunt, Sarah E., Lacerda, Henio G., Langford, Cordelia, Pearson, Richard, Pontes, Núbia N., Rai, Madhukar, Singh, S.P., Smith, Linda, Sousa, Olivia, Vukcevic, Damjan, Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N.A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Wilson, Mary E., Deloukas, Panos, Peltonen, Leena, Christiansen, Frank, Witt, Campbell, Jeronimo, Selma M.B., Sundar, Shyam, Spencer, Chris C.A., Blackwell, Jenefer M., Donnelly, Peter
Publicado 2013

The correlation between reading and mathematics ability at age twelve has a substantial genetic component

por Davis, Oliver S. P., Band, Gavin, Pirinen, Matti, Haworth, Claire M. A., Meaburn, Emma L., Kovas, Yulia, Harlaar, Nicole, Docherty, Sophia J., Hanscombe, Ken B., Trzaskowski, Maciej, Curtis, Charles J. C., Strange, Amy, Freeman, Colin, Bellenguez, Céline, Su, Zhan, Pearson, Richard, Vukcevic, Damjan, Langford, Cordelia, Deloukas, Panos, Hunt, Sarah, Gray, Emma, Dronov, Serge, Potter, Simon C., Tashakkori-Ghanbaria, Avazeh, Edkins, Sarah, Bumpstead, Suzannah J., Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Duncanson, Audrey, Jankowski, Janusz A. Z., Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Barroso, Ines, Peltonen, Leena, Dale, Philip S., Petrill, Stephen A., Schalkwyk, Leonard S., Craig, Ian W., Lewis, Cathryn M., Price, Thomas S., Donnelly, Peter, Plomin, Robert, Spencer, Chris C. A.
Publicado 2014