Pre-clinical efficacy and synergistic potential of the MDM2-p53 antagonists, Nutlin-3 and RG7388, as single agents and in combined treatment with cisplatin in ovarian cancer

por Zanjirband, Maryam, Edmondson, Richard J., Lunec, John
Publicado 2016

Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

por Zanjirband, Maryam, Curtin, Nicola, Edmondson, Richard J., Lunec, John
Publicado 2017

Comparison of two questionnaires to diagnose obstructive defecation syndrome during pregnancy and post-natally

por Sentance, Joanne, Stocking, Katie, Edmondson, Richard J., Kearney, Rohna
Publicado 2022

DNA damage repair in ovarian cancer: unlocking the heterogeneity

por Gee, Mary Ellen, Faraahi, Zahra, McCormick, Aiste, Edmondson, Richard J.
Publicado 2018

Engineering microrobots for targeted cancer therapies from a medical perspective

por Schmidt, Christine K., Medina-Sánchez, Mariana, Edmondson, Richard J., Schmidt, Oliver G.
Publicado 2020

Epithelial ovarian cancer risk: A review of the current genetic landscape

por Flaum, Nicola, Crosbie, Emma J., Edmondson, Richard J., Smith, Miriam J., Evans, Dafydd G.
Publicado 2019

First-Line Management of Advanced High-Grade Serous Ovarian Cancer

por Mahmood, Reem D., Morgan, Robert D., Edmondson, Richard J., Clamp, Andrew R., Jayson, Gordon C.
Publicado 2020

PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer

por Morgan, Robert D., Clamp, Andrew R., Evans, D. Gareth R., Edmondson, Richard J., Jayson, Gordon C.
Publicado 2018

A Prospective Study to Identify Rates of SARS-CoV-2 Virus in the Peritoneum and Lower Genital Tract of Patients Having Surgery: An Observational Study

por Jones, Dominique, Faluyi, David, Hamilton, Sarah, Stylianides, Nicholas, Ma, Ken, Duff, Sarah, Machin, Nicholas, Edmondson, Richard J.
Publicado 2021

Ex vivo expanded tumour-infiltrating lymphocytes from ovarian cancer patients release anti-tumour cytokines in response to autologous primary ovarian cancer cells

por Owens, Gemma L., Price, Marcus J., Cheadle, Eleanor J., Hawkins, Robert E., Gilham, David E., Edmondson, Richard J.
Publicado 2018

The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: A prospective case control study

por Kitson, Sarah J., Lindsay, Jennifer, Sivalingam, Vanitha N., Lunt, Mark, Ryan, Neil A.J., Edmondson, Richard J., Rutter, Martin K., Crosbie, Emma J.
Publicado 2018

Preclinical Assessment of CAR T-Cell Therapy Targeting the Tumor Antigen 5T4 in Ovarian Cancer

por Owens, Gemma L., Sheard, Victoria E., Kalaitsidou, Milena, Blount, Daniel, Lad, Yatish, Cheadle, Eleanor J., Edmondson, Richard J., Kooner, Gurdeep, Gilham, David E., Harrop, Richard
Publicado 2018

BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study

por Kitson, Sarah J., Bafligil, Cemsel, Ryan, Neil A.J., Lalloo, Fiona, Woodward, Emma R., Clayton, Richard D., Edmondson, Richard J., Bolton, James, Crosbie, Emma J., Evans, D. Gareth
Publicado 2020

The Use of Ovarian Cancer Cells from Patients Undergoing Surgery to Generate Primary Cultures Capable of Undergoing Functional Analysis

por O′Donnell, Rachel L., McCormick, Aiste, Mukhopadhyay, Asima, Woodhouse, Laura C., Moat, Madeleine, Grundy, Anna, Dixon, Michelle, Kaufman, Angelika, Soohoo, San, Elattar, Ahmed, Curtin, Nicola J., Edmondson, Richard J.
Publicado 2014

Functional characterisation of a novel ovarian cancer cell line, NUOC-1

por McCormick, Aiste, Earp, Eleanor, Elliot, Katherine, Cuthbert, Gavin, O'Donnell, Rachel, Wilson, Brian T., Sutton, Ruth, Leeson, Charlotte, Thomas, Huw D., Blair, Helen, Fordham, Sarah, Lunec, John, Allan, James, Edmondson, Richard J.
Publicado 2017

Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low l...

por Crosbie, Emma J., Flaum, Nicola, Harkness, Elaine F., Clayton, Richard D., Holland, Cathrine, Martin‐Hirsch, Pierre, Wood, Nick, Keating, Patrick, Woodward, Emma R., Lalloo, Fiona, Donnai, Paul, Edmondson, Richard J., Evans, D. Gareth
Publicado 2020

c-MET/VEGFR-2 co-localisation impacts on survival following bevacizumab therapy in epithelial ovarian cancer: an exploratory biomarker study of the phase 3 ICON7 trial

por Morgan, Robert D., Ferreras, Cristina, Peset, Isabel, Avizienyte, Egle, Renehan, Andrew G., Edmondson, Richard J., Murphy, Alexander D., Nicum, Shibani, Van Brussel, Thomas, Clamp, Andrew R., Lambrechts, Diether, Zhou, Cong, Jayson, Gordon C.
Publicado 2022

High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers

por Dent, Barry M., Ogle, Laura F., O'Donnell, Rachel L., Hayes, Nicholas, Malik, Ujjal, Curtin, Nicola J., Boddy, Alan V., Plummer, E. Ruth, Edmondson, Richard J., Reeves, Helen L., May, Felicity E.B., Jamieson, David
Publicado 2015

Investigating the Impact of Ultra-Radical Surgery on Survival in Advanced Ovarian Cancer Using Population-Based Data in a Multicentre UK Study

por Cummins, Carole, Kumar, Satyam, Long, Joanna, Balega, Janos, Broadhead, Tim, Duncan, Timothy, Edmondson, Richard J., Fotopoulou, Christina, Glasspool, Rosalind M., Kolomainen, Desiree, Leeson, Simon, Manchanda, Ranjit, Morrison, Jo, Naik, Raj, Tidy, John A., Wood, Nick, Sundar, Sudha
Publicado 2022

Ki-67 in endometrial cancer: scoring optimization and prognostic relevance for window studies

por Kitson, Sarah, Sivalingam, Vanitha N, Bolton, James, McVey, Rhona, Nickkho-Amiry, Mashid, Powell, Melanie E, Leary, Alexandra, Nijman, Hans W, Nout, Remi A, Bosse, Tjalling, Renehan, Andrew G, Kitchener, Henry C, Edmondson, Richard J, Crosbie, Emma J
Publicado 2017